Paid Clinical Trials in Massachusetts

Massachusetts has 3,584 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,584 clinical trials

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A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

24 locations incl. Chula Vista

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting

Apply to this trial

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

Apply to this trial

Deep Brain Stimulation (DBS) MatchMaker

for TOR1A

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06912841·Enrolling By Invitation

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

for Alcohol Use Disorder

2 locations incl. Farmington

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14 - 21

Code: NCT06395467·Recruiting

Apply to this trial

Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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BCL2i CLAG-M in R/R Acute Myeloid Leukemia

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18 - 80

Code: NCT06660368·Phase 2·Recruiting

Apply to this trial

A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

for Skin Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06664151·EARLY_Phase 1·Recruiting

Apply to this trial

Promoting Early Intervention Timing and Attention to Language

for MONITOR

2 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 6 Months - 8 Months

Code: NCT05853861·Recruiting

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ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

for Advanced Solid Tumor

5 locations incl. Rogers

Sponsor: Adcendo ApS

Sex: All·Age: 18+

Code: NCT06597721·Phase 1·Recruiting

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

37 locations incl. Dothan

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06690398·Phase 3·Recruiting

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

54 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

Apply to this trial

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

26 locations incl. Duarte

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting

Apply to this trial

A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

for Neovascular Age-related Macular Degeneration

18 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 50 - 90

Code: NCT06660667·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

30 locations incl. Birmingham

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06701903·Phase 2·Recruiting

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Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

for Lymphoma

Drug: Epcoritamab

3 locations incl. Stanford

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06510361·Phase 2·Recruiting

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

Apply to this trial

Just-in-time Interventions for Reducing Short-term Suicide Risk

for Suicide

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05793541·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

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A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

for Hormone Receptor Positive HER-2 Negative Breast Cancer

35 locations incl. Birmingham

Sponsor: Puma Biotechnology, Inc.

Sex: All·Age: 18+

Code: NCT06369285·Phase 2·Recruiting

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Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML

for Leukemia

53 locations incl. Goodyear

Sponsor: Daiichi Sankyo

Sex: All·Age: 18 - 70

Code: NCT06578247·Phase 3·Recruiting

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Trial of the Impact of Sibeprenlimab on Immunoglobulin A Nephropathy Kidney Tissue

for IgA Nephropathy

4 locations incl. Denver

Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc.

Sex: All·Age: 16+

Code: NCT06740526·Phase 2·Recruiting

Apply to this trial

Virtual Reality to Combat Weight-Based Implicit Bias: BWH Pilot Study

for Implicit Bias

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283523·Enrolling By Invitation

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

for Congenital Heart Disease

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Day - 12

Code: NCT05687292·Recruiting

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Evaluating Interventions for Intimate Partner Violence Use in Washington State

for Intimate Partner Violence

1 location in Boston

Sponsor: Boston University

Sex: All·Age: 18+

Code: NCT06526247·Recruiting

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

50 locations incl. Montgomery

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting

Apply to this trial

REcovery From DEXmedetomidine-induced Unconsciousness

for Anesthesia

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06003127·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called Rimegepant in Adolescents With Frequent Migraine

for Migraine

Drug: Rimegepant

27 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT06616194·Phase 3·Recruiting

Apply to this trial

Mind Body Intervention for Chronic Migraine Headaches

for Migraines

2 locations incl. Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06690060·Recruiting

Apply to this trial

Avelumab and M1774 in ARID1A-mutated Endometrial Cancer

for Endometrial Cancer

2 locations incl. Boston

Sponsor: Panagiotis Konstantinopoulos, MD, PhD

Sex: Female·Age: 18+

Code: NCT06518564·Phase 2·Recruiting

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A Study to Evaluate Safety, Pharmacokinetics, and Activity of GDC-7035 as a Single Agent and in Combination in Patients With Advanced Solid Tumors

for Solid Tumor

12 locations incl. La Jolla

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT06619587·Phase 1·Recruiting

Apply to this trial

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

for Solid Tumors

3 locations incl. Boston

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06644755·Phase 1·Recruiting

Apply to this trial

Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B

for HEPATITIS B CHRONIC

1 location in Boston

Sponsor: Precision BioSciences, Inc.

Sex: All·Age: 18 - 70

Code: NCT06680232·Phase 1·Recruiting

Apply to this trial

Real-world Effectiveness of HPV Vaccine in Women Living With HIV and Its Impact on Cervical Cancer Screening Accuracies

for Hiv

9 locations incl. Denver

Sponsor: University of California, Los Angeles

Sex: Female·Age: 21 - 40

Code: NCT06144229·Enrolling By Invitation

Adolescent Outcomes of Post-operative Opioid EXposure

for Opioid Use Disorder

5 locations incl. Aurora

Sponsor: Sharon Levy

Sex: All·Age: 12 - 17

Code: NCT06350409·Recruiting

Apply to this trial

Acceptability and Safety of MR-C-014 in Persons With Neuromyelitis Optica Spectrum Disorder

for Neuromyelitis Optica Spectrum Disorder

2 locations incl. Atlanta

Sponsor: MedRhythms, Inc.

Sex: All·Age: 18 - 70

Code: NCT06374264·Enrolling By Invitation

Early Internal Fixation Versus NonOperative Care With Early Rehabilitation for LC1 Fragility Fractures of the Pelvis

for Multiple Closed Pelvic Fractures With Disruption of Pelvic Ring

12 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 60+

Code: NCT06496867·Recruiting

Apply to this trial

Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

5 locations incl. Gainesville

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting

Apply to this trial

Xeltis Hemodialysis Access Graft (aXess) US Study

for End Stage Renal Disease

7 locations incl. Phoenix

Sponsor: Xeltis

Sex: All·Age: 18+

Code: NCT06494631·Enrolling By Invitation

Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

for Otoferlin Gene-mediated Hearing Loss

3 locations incl. Iowa City

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT06696456·Enrolling By Invitation