Paid Clinical Trials in Massachusetts

Massachusetts has 3,584 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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3,584 clinical trials

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

13 locations incl. Los Angeles

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting

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Suprachoroidal Administration in Subjects With Metastases to the Choroid

for Eye Cancer

10 locations incl. Palo Alto

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06643884·Phase 2·Recruiting

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

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A Study of Belantamab Mafodotin Administered in Combination With Lenalidomide and Dexamethasone (BRd) Versus Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) Who Are Ineligible for Autologous Stem Cell Transplantation (TI-NDMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

30 locations incl. Mobile

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT06679101·Phase 3·Recruiting

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Future Leaders Program: Testing a Youth Leadership, Engagement, and Mindfulness Program

for Adolescent Behavior Problem

3 locations incl. Chicago

Sponsor: Boston University Charles River Campus

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT06736522·Recruiting

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Phase 1 Study of OP-3136 in Advanced or Metastatic Solid Tumors

for Advanced or Metastatic ER+ HER2- Breast Cancer (mBC)

7 locations incl. Sarasota

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06784193·Phase 1·Recruiting

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Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

for Parenteral Nutrition Associated Liver Disease (PNALD)

10 locations incl. Fountain Valley

Sponsor: Fresenius Kabi

Sex: All·Age: 1 Day - 17

Code: NCT06274788·Recruiting

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The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

for Rectal Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06565052·Recruiting

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Physiology of Human Brain Connectivity

for Healthy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT06246942·Recruiting

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

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First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

for Advanced Solid Tumors

12 locations incl. New Haven

Sponsor: Tubulis GmbH

Sex: All·Age: 18+

Code: NCT06657222·Phase 1, Phase 2·Recruiting

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Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

for Pancreatic Carcinoma

9 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06271291·Recruiting

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A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

for Asthma

85 locations incl. Phoenix

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 12+

Code: NCT06664619·Phase 3·Recruiting

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Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

13 locations incl. Tucson

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting

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Study to Evaluate Ultevursen in Subjects With Retinitis Pigmentosa (RP) Due to Mutations in Exon 13 of the USH2A Gene

for Retinitis Pigmentosa (RP)

11 locations incl. San Francisco

Sponsor: Laboratoires Thea

Sex: All·Age: 8+

Code: NCT06627179·Phase 2·Recruiting

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Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer

for Resectable Lung Non-Small Cell Carcinoma

378 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06632327·Phase 3·Recruiting

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Dose Escalation and Expansion Study of HM16390 Alone or With Pembrolizumab in Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumors

2 locations incl. Boston

Sponsor: Hanmi Pharmaceutical Company Limited

Sex: All·Age: 18+

Code: NCT06724016·Phase 1·Recruiting

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Can Food Timing Reduce Your Diabetes Risk?

for Dietary Habits

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05862818·Recruiting

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A Master Protocol to Evaluate DCC-3009 in Gastrointestinal Stromal Tumor (GIST)

for Gastrointestinal Stromal Tumor (GIST)

10 locations incl. Scottsdate

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06630234·Phase 1, Phase 2·Recruiting

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Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults

for Cannabis Use Disorder

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 26

Code: NCT06661031·Enrolling By Invitation

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

for Blood Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06469307·Recruiting

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A Clinical Registry to Demonstrate the Safety and Performance of Teleflex Vascular Access Devices

for Vascular Access Device

3 locations incl. Huntsville

Sponsor: Teleflex

Sex: All·Age: All ages

Code: NCT06604039·Recruiting

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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for COVID-19 SARS-CoV-2 Infection

84 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06679140·Phase 3·Recruiting

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Revumenib in Combination With 7+3 + Midostaurin in AML

for Acute Myeloid Leukemia

Drug: Revumenib

2 locations incl. New Haven

Sponsor: Richard Stone, MD

Sex: All·Age: 18 - 75

Code: NCT06313437·Phase 1·Recruiting

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Epcoritamab in Previously Treated WM

for Waldenstrom Macroglobulinemia

Drug: Epcoritamab

3 locations incl. Boston

Sponsor: Gottfried von Keudell, MD PhD

Sex: All·Age: 18+

Code: NCT06510491·Phase 2·Recruiting

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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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Testing the mHealth App Intervention for Nondaily Smokers "SiS4"

for Smoking Cessation

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06678243·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

39 locations incl. Little Rock

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06706674·Phase 3·Recruiting

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

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CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

for Chronic Pain

4 locations incl. Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 75

Code: NCT06027099·Phase 3·Recruiting

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Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

for Appetitive Behavior

2 locations incl. Belmont

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06105164·Recruiting

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Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis

for Multiple Sclerosis

6 locations incl. Washington D.C.

Sponsor: Accelerated Cure Project for Multiple Sclerosis

Sex: All·Age: 22+

Code: NCT06441617·Recruiting

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Kidney Blood Flow During Exercise in Older African American Adults

for Healthy

1 location in Boston

Sponsor: University of Massachusetts, Boston

Sex: All·Age: 55 - 79·Accepts healthy volunteers

Code: NCT07029165·Recruiting

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A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

for Neurofibromatosis 1

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: All ages

Code: NCT06262113·Recruiting

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Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

for Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)

9 locations incl. Denver

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06465953·Phase 3·Recruiting

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Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for Patients With Non-Small Cell Lung Cancer

79 locations incl. Beverly Hills

Sponsor: OSE Immunotherapeutics

Sex: All·Age: 18+

Code: NCT06472245·Phase 3·Recruiting

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OurSleepKit To Support CPAP Adherence

for Obstructive Sleep Apnea

2 locations incl. Boston

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18+

Code: NCT06621511·Recruiting

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A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

24 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06679946·Phase 3·Enrolling By Invitation

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

for HIV Infections

41 locations incl. Birmingham

Sponsor: ViiV Healthcare

Sex: All·Age: 12+

Code: NCT06694805·Phase 3·Recruiting

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Drug Screening Using Novel IMD in Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Boston

Sponsor: Oliver Jonas

Sex: All·Age: 18+

Code: NCT05700461·Phase 1·Recruiting

Apply to this trial