Paid Clinical Trials in Massachusetts

Massachusetts has 3,587 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,587 clinical trials

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Post-market Clinical Investigation Plan: Collagen Dura Regeneration Membrane - Repair (DMR)

for Repair of Dura Mater

2 locations incl. Chicago

Sponsor: Collagen Matrix

Sex: All·Age: 18+

Code: NCT07371091·Not Yet Recruiting

B7-H3.CD28Z.CART in CNS Neoplasms

for Central Nervous System Neoplasms

2 locations incl. Boston

Sponsor: Robbie Majzner

Sex: All·Age: 2 - 21

Code: NCT07390539·Phase 1·Not Yet Recruiting

The DISCOVER Study

for Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07390643·Not Yet Recruiting

Assessing DCog Short for Neurotoxicity in CAR-T

for Neurotoxicity

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07403812·Not Yet Recruiting

Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy

for Cutaneous Squamous Cell Carcinoma

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07426484·Phase 4·Not Yet Recruiting

Assessing PI3K Gamma Inhibition With Azacitidine, Venetoclax and Eganelisib in Patients With Acute Myeloid Leukemia

for Leukemia, Myeloid

Drug: Venetoclax

2 locations incl. Boston

Sponsor: Jacqueline Garcia, MD

Sex: All·Age: 18 - 90

Code: NCT07439211·Phase 1·Not Yet Recruiting

STABLE Pilates for Hypermobility

for Ehlers-Danlos Syndrome (EDS)

1 location in Chestnut Hill

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT07464093·Recruiting

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Validation of the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for Adolescents

for Vestibular Migraine

3 locations incl. Needham

Sponsor: Boston Children's Hospital

Sex: All·Age: 10 - 20·Accepts healthy volunteers

Code: NCT07532109·Not Yet Recruiting

Creation of a Decision Aid for Coronary Anomalies

for AAOCA

5 locations incl. Boston

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 10 - 35

Code: NCT07544979·Not Yet Recruiting

Using Virtual Reality to Teach Mindfulness to People With Migraine

for Migraine Disorders

3 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT07599228·Not Yet Recruiting

Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension (PAH)

10 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 18 - 75

Code: NCT07601295·Phase 2·Not Yet Recruiting

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

for Chronic Pain

Drug: LY4065967

36 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07641504·Phase 2·Not Yet Recruiting

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

for Osteoarthritis, Knee

Drug: LY4065967

36 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 40+

Code: NCT07641517·Phase 2·Not Yet Recruiting

Bempedoic Acid Therapy for Polycystic Kidney Disease

for ADPKD (Autosomal Dominant Polycystic Kidney Disease)

Drug: Bempedoic acid

3 locations incl. Baltimore

Sponsor: Kenneth Hallows

Sex: All·Age: 18 - 60

Code: NCT07282821·Phase 2·Not Yet Recruiting

A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

7 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Not Yet Recruiting

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for Solid Tumors

18 locations incl. San Francisco

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07492680·Phase 2·Not Yet Recruiting

Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts

for Fatigue

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06100809·Not Yet Recruiting

Effect of PEEP on Cardiac Function

for Cardiac Surgery Subjects

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07531602·Not Yet Recruiting

Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML

for KMT2A-rearranged

Drug: Mezigdomide

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT07355335·Phase 1·Not Yet Recruiting

CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis

for Antineutrophil Cytoplasmic Antibody-associated Vasculitis

1 location in Boston

Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All·Age: 18+

Code: NCT07388277·Phase 1, Phase 2·Recruiting

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The Care for America's Aging Study

for Cognitive Impairment

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06021704·Not Yet Recruiting

Impacts of Opioids on Respiratory Drive During Sleep

for Opioids

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06854211·EARLY_Phase 1·Not Yet Recruiting

Evaluating the Efficacy of a Vocational Counseling Intervention to Improve Occupational Functioning and Employment Quality Among Veterans With Mental Health and Substance Use Disorders

for Unemployment

3 locations incl. Hines

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07097376·Not Yet Recruiting

Development and Feasibility of CTraC-FIT

for Functional Impairment

1 location in Boston

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT07132944·Not Yet Recruiting

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

for Heart Failure With Preserved Ejection Fraction

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40+

Code: NCT07202000·Phase 2·Not Yet Recruiting

(TNX-1500) in Kidney Transplant Recipients

for Kidney Transplant

2 locations incl. Boston

Sponsor: Ayman Al Jurdi, MD

Sex: All·Age: 18 - 75

Code: NCT07204080·Phase 2·Not Yet Recruiting

COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"

for New Onset Refractory Status Epilepticus

Drug: Tocilizumab

25 locations incl. Phoenix

Sponsor: Yale University

Sex: All·Age: 2+

Code: NCT07281027·Phase 3·Not Yet Recruiting

CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic Shock

for Cardiogenic Shock

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 80

Code: NCT07461961·Phase 2·Not Yet Recruiting

Testing an Adaptive Intervention for Peer-Supported Mobile Health for Primary Care Veterans With Psychological Distress

for Psychological Distress

5 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07507747·Not Yet Recruiting

Risk-adapted Therapy in HPV-positive Oropharyngeal Cancer Using Circulating Tumor (ct) HPV DNA Profiling (ReACT 2.0)

for HPV-positive Oropharyngeal Squamous Cell Carcinoma

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07513324·Phase 2·Not Yet Recruiting

Role of n On-contrast Chest CT (NCCT) Based CT V: Q in Patients With Acute Pulmonary Embolism (aPE)

for Pulmonary Embolism (Diagnosis)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 21+

Code: NCT07527117·Not Yet Recruiting

Study of EPN-701 for the Treatment of Calciphylaxis

for Calciphylaxis

1 location in Boston

Sponsor: Sagar U. Nigwekar, MD, MMSc

Sex: All·Age: 18+

Code: NCT07583745·Phase 2·Not Yet Recruiting

The Effect of Static Magnetic Fields on Neuroinflammation in Migraine

for Migraine in Adults

1 location in Charlestown

Sponsor: Marco Loggia

Sex: All·Age: 18 - 65

Code: NCT07584382·Not Yet Recruiting

Synaptic Mechanisms of Intermittent Theta Burst Stimulation for Major Depressive Disorder

for Major Depression

1 location in Belmont

Sponsor: Mclean Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07593222·Phase 1, Phase 2·Not Yet Recruiting

Improving Jail Response to the Overdose Crisis: A Hybrid Trial of Jail ECHO to Improve MOUD Implementation and Public Health Outcomes

for Opioid Abuse (Disorder)

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07637994·Not Yet Recruiting

Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents: A Clinical Effectiveness Study

for Pediatric Chronic Neuropathic Pain

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 8 - 18

Code: NCT02219373·Phase 3·Not Yet Recruiting

Polarization Sensitive Optical Coherence Tomography (PS-OCT) for Retinal Imaging

for Healthy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT02441777·Not Yet Recruiting

Cenobamate in the Intensive Care Unit

for Epilepsy

Drug: Cenobamate

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT06352723·EARLY_Phase 1·Not Yet Recruiting

Carbohydrate Fluids and Post Operative Nausea and Vomiting

for Nausea, Postoperative

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 19+

Code: NCT06481670·Not Yet Recruiting

Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques

for Carotid Artery Diseases

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06957821·EARLY_Phase 1·Not Yet Recruiting