The Effect of Static Magnetic Fields on Neuroinflammation in Migraine

Part of paid clinical trials in Charlestown, Massachusetts.

Sponsor
Marco Loggia
Study ID
NCT07584382
Status
Not Yet Recruiting

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Conditions

  • Migraine in Adults

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Static magnetic helmet — DEVICE
    Participants will wear a static magnetic helmet for 20 minutes daily during a 21-day intervention period

Study Details

We are conducting this research in individuals with migraines to find out if a daily magnet helmet application could alter migraine-related brain inflammation. Outcomes will be assessed through examining any changes in Translocator Protein (TSPO) binding on Positron Emission Tomography-Computed Tomography (PET-CT) imaging both before and after the magnet helmet intervention period. Additionally, patient-reported migraine symptoms will be measured using validated questionnaires administered during the four-week pre- and post- intervention monitoring periods.

Key Dates

Start date
Jul 1, 2026
Status verified
May 2026
Primary completion
Jul 1, 2027
Completion
Sep 1, 2027

Study Design

Enrollment
10 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Patients with Migraine
    This arm will undergo the 21-day at-home self-administered non-drug intervention

Primary Outcome Measure

Regional Brain [11C]PBR28 PET Signal [ Time Frame: From the pre-intervention scan to the post-intervention scan, approximately 21 days later ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
A.A. Martinos Center for Biomedical ImagingCharlestownMassachusetts02129
Marco L Loggia, PhD
[email protected]
617-643-7267
Marco L Loggia, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Charlestown, MA

By research site
A.A. Martinos Center for Biomedical Imaging· Charlestown, MA

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