Mental health Clinical Trials in Los Angeles, CA

As of June 2026, 71 paid clinical trials are recruiting for Mental health in Los Angeles, California. Mental health research covers new pharmacotherapies, psychotherapies, and digital interventions for depression, anxiety, PTSD, bipolar disorder, and sleep — including treatments for treatment-resistant cases. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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71 clinical trials for Mental health

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The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans

for Post Traumatic Stress Disorder

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06218381·Recruiting

Apply to this trial

Regulation of Affect and Physiology in Depression

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18 - 27·Accepts healthy volunteers

Code: NCT06345859·Phase 2·Recruiting

Apply to this trial

Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder

for MDD

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 21 - 75

Code: NCT06572683·Enrolling By Invitation

Multi-center Trial to Improve Nocturia and Sleep in Older Adults

for Nocturia

2 locations incl. Los Angeles

Sponsor: Atlanta VA Medical Center

Sex: All·Age: 60+

Code: NCT06110091·Recruiting

Apply to this trial

AWARE: Management of ADHD in Autism Spectrum Disorder

for ADHD

10 locations incl. Irvine

Sponsor: Daniel Coury

Sex: All·Age: 4 - 17

Code: NCT05916339·Phase 4·Recruiting

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Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

for Depression

10 locations incl. Costa Mesa

Sponsor: Kernel

Sex: All·Age: 18 - 75

Code: NCT06002100·Enrolling By Invitation

Determining the Role of Social Reward Learning in Social Anhedonia

for Psychosis

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 35

Code: NCT05617898·Recruiting

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Study of ALTO-300 in MDD

for Major Depressive Disorder

45 locations incl. Phoenix

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 70

Code: NCT05922878·Phase 2·Recruiting

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Improving Cognition Through Telehealth Aerobic Exercise and Cognitive Training After a First Schizophrenia Episode

for Schizophrenia

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 45

Code: NCT05890183·Recruiting

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Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder

for Tourette's Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 50

Code: NCT05499741·Recruiting

Apply to this trial

Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy

for Depression

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 40

Code: NCT05908565·Recruiting

Apply to this trial

Pain and Major Depressive Disorder

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 75

Code: NCT04556890·Recruiting

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SAFETY-A for Promoting Equity in Suicide Prevention Outcomes in Schools

for Suicidal Ideation

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 11+

Code: NCT05834660·Recruiting

Apply to this trial

Feasibility Study of Oral Ketamine Versus Placebo for the Treatment of Anxiety in Patients With Pancreatic Cancer

for Anxiety

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT05086250·EARLY_Phase 1·Recruiting

Apply to this trial

Evaluating tDCS Brain-stimulation in Depression Using MRI

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 20 - 55

Code: NCT05598034·Recruiting

Apply to this trial

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

for Suicide

5 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 13 - 24

Code: NCT05304065·Phase 2·Recruiting

Apply to this trial

S.T.A.N.D. Alacrity Center Signature Project

for Depression

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 40

Code: NCT05591937·Recruiting

Apply to this trial

Children's Bipolar Network Treatment Trial I

for Bipolar Disorder

4 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 9 - 19

Code: NCT05427123·Recruiting

Apply to this trial

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

for Schizophrenia

7 locations incl. Los Angeles

Sponsor: New York State Psychiatric Institute

Sex: All·Age: 18 - 65

Code: NCT05208190·Phase 4·Recruiting

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An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

for Schizophrenia

Drug: KarXT

79 locations incl. Phoenix

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 18 - 65

Code: NCT05304767·Phase 3·Recruiting

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Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children

for Sedentary Behavior

1 location in Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 8 - 11·Accepts healthy volunteers

Code: NCT04469790·Recruiting

Apply to this trial

Social Support and Reduced Fear Acquisition

for Fear

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT04564976·Recruiting

Apply to this trial

Social Support and Enhanced Fear Extinction

for Fear

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT04565041·Recruiting

Apply to this trial

Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

for Fear

2 locations incl. Los Angeles

Sponsor: Duke University

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT05120635·Recruiting

Apply to this trial

Psychostimulant Augmentation of Repetitive TMS for the Treatment of Major Depressive Disorder

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 65

Code: NCT04509102·EARLY_Phase 1·Enrolling By Invitation

Low-Intensity Focused Ultrasound Pulsation (LIFUP) for the Treatment of Generalized Anxiety Disorder (GAD)

for Generalized Anxiety Disorder

3 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 65

Code: NCT04557891·Recruiting

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Responsive Neurostimulation for Post-Traumatic Stress Disorder

for Post-Traumatic Stress Disorder

1 location in Los Angeles

Sponsor: VA Greater Los Angeles Healthcare System

Sex: Male·Age: 25 - 60

Code: NCT04152993·EARLY_Phase 1·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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The Role of Virtual Reality During Regional Anesthesia

for Anxiety

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT04163809·Recruiting

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

98 locations incl. Birmingham

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting

Apply to this trial

Spectral TMS (s-TMS)

for Major Depressive Disorder

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 65

Code: NCT04040062·Enrolling By Invitation

Conditions in Mental health (Los Angeles, CA)

Depression· 33 Anxiety· 17 PTSD (post-traumatic stress disorder)· 8 Schizophrenia· 7 Suicidal ideation / suicide· 4 Insomnia· 4 ADHD· 3 Bipolar disorder· 1