Mental health Clinical Trials in Los Angeles, CA
As of June 2026, 71 paid clinical trials are recruiting for Mental health in Los Angeles, California. Mental health research covers new pharmacotherapies, psychotherapies, and digital interventions for depression, anxiety, PTSD, bipolar disorder, and sleep — including treatments for treatment-resistant cases. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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71 clinical trials for Mental health
·Clear filters·↓ Download CSVA Phase I/II Study of PDC-1421 for Treating Depression in Cancer Patients
Crisis Interventions for Pediatric Providers - Autism Version
VR Therapies for IBD
Active vs. Passive VR During Office-based ENT Procedures
Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV
Health And Response: Digital Markers for Outcomes in Perinatal Depression Treatment Study
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
Biomolecular Characteristics of Reminder-Focused Positive-Psychiatry
A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression
Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies
Prediction of REsponse to Depression Interventions (Accelerated rTMS) Using Clinical and TD-fNIRS Measurements
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Living Well Program: Impact on Healthcare Costs and Clinical Outcomes in Breast Cancer Care
A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder
Suvorexant for Treatment of AUD and PTSD
RCT for Latina Mental Health Using Web-Based Apps
Training Reward Responsiveness Through Virtual Reality
E-Mindfulness Approaches for Living After Breast Cancer
Bridge the Gap (BTG) - Black Youth Group
NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Improving Behavioral Health for Caregivers and Children After Pediatric Injury
Assessing Improvements in Mood and Sleep Trial
Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
In-patient SCC TMS
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
Tolerability of MDMA in Schizophrenia
An Open-Label Study of Azetukalner in Major Depressive Disorder
MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder
K08 VR Fear Conditioning
Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Music-Based Interventions, Aging, Alzheimer's Disease
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Study of ALTO-101 in Patients With Schizophrenia
Low-dose Buprenorphine as a Modulator of Social Motivation in Schizophrenia
About research studies in Los Angeles
Los Angeles has approximately 2,062 recruiting research studies across a wide range of therapeutic areas. California hosts a dense network of world-class research institutions, including UC San Diego Health, Stanford Medicine, UCLA Health, UCSF, City of Hope, and Scripps Research. The state's thriving biotech corridor and diverse patient population make it a national hub for both early-phase and late-phase clinical research.
Top Research Study Locations in Los Angeles
Researchers run research studies in Los Angeles, CA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cedars-Sinai Medical Center | Breast Cancer, Acute Myeloid Leukemia, Chronic Pancreatitis | 230 |
| Children's Hospital Los Angeles | Neuroblastoma, Acute Myeloid Leukemia, Anesthesia | 129 |
| University of California, Los Angeles | Alzheimer Disease, Depression, Focal Epilepsy | 113 |
| University of Southern California | Acute Pancreatitis, Amyotrophic Lateral Sclerosis, Breast Cancer | 100 |
| USC / Norris Comprehensive Cancer Center | Malignant Solid Neoplasm, Breast Carcinoma, Hematopoietic and Lymphatic System Neoplasm | 85 |
| Cedars Sinai Medical Center | Aortic Dissection, Crohn's Disease, Heart Failure | 74 |
| UCLA / Jonsson Comprehensive Cancer Center | Prostate Carcinoma, Prostate Adenocarcinoma, Stage II Prostate Cancer AJCC v8 | 71 |
| University of California Los Angeles | Parkinson Disease, Bladder Cancer, Breast Cancer | 71 |
| Los Angeles General Medical Center | Metastatic Malignant Solid Neoplasm, Stage IVB Prostate Cancer AJCC v8, Unresectable Malignant Solid Neoplasm | 67 |
| UCLA | Bladder Cancer, COVID-19, Colorectal Cancer | 58 |
| USC Norris Comprehensive Cancer Center | Colorectal Cancer, Endometrial Cancer, Head and Neck Squamous Cell Carcinoma | 53 |
| Kaiser Permanente Los Angeles Medical Center | Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 51 |
| Children's Hospital of Los Angeles | Acute Lymphoblastic Leukemia, Cystic Fibrosis, 4H Syndrome | 40 |
| Valkyrie Clinical Trials | Multiple Myeloma, Solid Tumors, Advanced Solid Tumors | 35 |
| Ronald Reagan UCLA Medical Center | Ischemic Stroke, Stroke, Esophageal Adenocarcinoma | 27 |
| USC/Norris Comprehensive Cancer Center | Breast Cancer, Breast Neoplasms, Bladder Cancer | 27 |
| UCLA Medical Center | Colorectal Cancer, CRC, Cancer | 22 |
| Kaiser Permanente West Los Angeles | Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | 20 |
| Keck Medicine of USC Koreatown | Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction Adenocarcinoma | 19 |
| David Geffen School of Medicine at UCLA | Developmental and Epileptic Encephalopathy, Advanced Solid Tumor, Candidemia | 15 |
| Cedars-Sinai | Crohn Disease, Coronary Artery Disease, Gaucher Disease | 13 |
| Keck Hospital of USC | Advanced or Metastatic Solid Tumors, Airway Disease, Airway Management | 13 |
| Mattel Children's Hospital UCLA | Malignant Solid Neoplasm, Ganglioneuroblastoma, Nodular, Hematopoietic and Lymphatic System Neoplasm | 13 |
| University of California at Los Angeles | ASD, Advanced Tumors, Alzheimer's Disease | 13 |
| University of California, Los Angeles (UCLA) | Adamantinomatous Craniopharyngioma, Adenosine Deaminase Severe Combined Immune Deficiency, Angelman Syndrome | 13 |
Active & Upcoming Studies in Los Angeles (2026)
Recruiting trials in Los Angeles grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (671 active studies)
- Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer · Phase 2 · Jonsson Comprehensive Cancer Center
- GYN-AIDE: Gynecologic Oncology Navigation Through AI-Driven Education · University of Southern California
Neurology & pain (121 active studies)
- Morphine or Ketamine for Analgesia · Phase 3 · Columbia University
- Measuring Pelvic Floor Muscle Fitness Before and After Treatment · University of California, Los Angeles
Cardiovascular (99 active studies)
Mental health & behavior (63 active studies)
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
- Group PACBT for Depression · Phase 2 · University of California, Los Angeles
Diabetes & metabolic (62 active studies)
- Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese · Phase 2 · Biomed Industries, Inc.
- A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity · Phase 2 · Novo Nordisk A/S
Pediatric (37 active studies)
- Early Re-Initiation of Semaglutide Post Sleeve Gastrectomy in Youth · Phase 3 · Children's Hospital Los Angeles
- Reference Range Study for the Quantra System With the QPlus Cartridge in Pediatric Patients · HemoSonics LLC
HIV / STI (26 active studies)
- Evaluating a Clinical Decision Support Tool for Antiretroviral Therapy Optimization · Keck School of Medicine of USC
- A Social Network Approach to Improve HIV Prevention and Substance Use Treatment For People Who Use Drugs · NYU Langone Health
Eye & vision (13 active studies)
- Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension · Stanford University
- This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to Study CDE and Ultrasound Time During Cataract Removal · Nicole Fram M.D.
Vaccines (11 active studies)
Common conditions studied in Los Angeles
- Breast Cancer (48 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Colorectal Cancer (28 active studies). Colorectal cancer trials explore novel chemotherapy combinations, targeted agents, and immunotherapy for microsatellite-instability-high tumors.
- Prostate Cancer (28 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Heart Failure (22 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Ovarian Cancer (22 active studies). Ovarian cancer research examines PARP inhibitors, maintenance therapies, and antibody-drug conjugates for recurrent and platinum-resistant disease.
- Advanced Solid Tumor (21 active studies). Recruiting Advanced Solid Tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes.
Leading research sponsors in Los Angeles
- University of California, Los Angeles
- University of Southern California
- Cedars-Sinai Medical Center
- Jonsson Comprehensive Cancer Center
- National Cancer Institute (NCI)
Local regulations and guidelines
Clinical trials in California are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. In addition, California-specific protections such as the California Consumer Privacy Act (CCPA) and the Confidentiality of Medical Information Act (CMIA) impose stringent data-privacy requirements on research involving California residents.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Los Angeles. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Los Angeles
Hipa.ai aggregates every recruiting study in Los Angeles from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Los Angeles?
There are approximately 2,062 recruiting clinical trials in Los Angeles, California listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Los Angeles pay participants?
Most recruiting trials in Los Angeles compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Los Angeles?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Los Angeles?
The most common conditions under active study in Los Angeles include Breast Cancer (48), Colorectal Cancer (28), Prostate Cancer (28), Heart Failure (22), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Los Angeles?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Los Angeles on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Los Angeles?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Los Angeles?
Recruiting research sites in Los Angeles include Cedars-Sinai Medical Center, Children's Hospital Los Angeles, University of California, Los Angeles, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Los Angeles right now?
The largest active categories in Los Angeles are Cancer & tumors (671), Neurology & pain (121), Cardiovascular (99). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.