Paid Clinical Trials in Indianapolis, IN

As of June 2026, 932 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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932 clinical trials

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

107 locations incl. Phoenix

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting

Apply to this trial

Pancreatic Quantitative Sensory Testing (P-QST) to Predict Treatment Response for Pain in Chronic Pancreatitis

for Chronic Pancreatitis

3 locations incl. Indianapolis

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04996628·Recruiting

Apply to this trial

Biomarker of Diabetic Retinopathy

for Diabetic Retinopathy

3 locations incl. Carmel

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05079399·Recruiting

Apply to this trial

Primary Sclerosing Cholangitis in Children

for Primary Sclerosing Cholangitis

11 locations incl. Los Angeles

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 2 - 25

Code: NCT04181138·Recruiting

Apply to this trial

Study to Determine the Dose and Safety of Asciminib in Pediatric Patients With Chronic Myeloid Leukemia

for Myeloid Leukemia, Philadelphia Positive

8 locations incl. Indianapolis

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 1 - 17

Code: NCT04925479·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

46 locations incl. Phoenix

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting

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First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

24 locations incl. Tucson

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting

Apply to this trial

Daily Hand-Held Vibration Therapy

for Neuropathy

3 locations incl. Avon

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT04207437·Recruiting

Apply to this trial

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

21 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting

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Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma and Other Solid Tumors, Receiving Intravenous Infusion of Azirkitug Alone or in Combination(s) With Budigalimab, Bevacizumab, or Telisotuzumab Adizutecan

for Non-Small Cell Lung Cancer

Drug: Bevacizumab

18 locations incl. Duarte

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT05005403·Phase 1·Recruiting

Apply to this trial

American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

Apply to this trial

Sentinel Lymph Node Biopsy for Cutaneous Squamous Cell Carcinoma of the Head and Neck

for Squamous Cell Carcinoma

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT05108090·Recruiting

Apply to this trial

Long-term Safety Extension Study of OLZ/SAM in Pediatric Subjects

for Bipolar I Disorder

14 locations incl. Dothan

Sponsor: Alkermes, Inc.

Sex: All·Age: 10 - 17

Code: NCT04987229·Phase 3·Enrolling By Invitation

Hepatic Impairment With Cirrhosis Due to Cholestatic Liver Disease

for Hepatic Impairment

1 location in Indianapolis

Sponsor: Zydus Therapeutics Inc.

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT05045482·Phase 1·Recruiting

Apply to this trial

Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

Apply to this trial

PSMA-PET to Guide Prostatectomy

for Prostate Cancer

1 location in Indianapolis

Sponsor: Five Eleven Pharma, Inc.

Sex: Male·Age: 40 - 80

Code: NCT05381103·Phase 2, Phase 3·Recruiting

Apply to this trial

Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

Apply to this trial

Long-term Safety and Efficacy of Odevixibat in Patients With Alagille Syndrome

for Alagille Syndrome

18 locations incl. San Diego

Sponsor: Albireo, an Ipsen Company

Sex: All·Age: All ages

Code: NCT05035030·Phase 3·Recruiting

Apply to this trial

Locomotor Recovery and Compensation Post-stroke (LRC)

for Stroke

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 85

Code: NCT05081713·Recruiting

Apply to this trial

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction

for Acute Myocardial Infarction

Drug: Selatogrel

81 locations incl. Alexander City

Sponsor: Viatris Innovation GmbH

Sex: All·Age: 18+

Code: NCT04957719·Phase 3·Enrolling By Invitation

IT Matters: The Erectile Restoration Registry

for Erectile Dysfunction

21 locations incl. Los Angeles

Sponsor: Boston Scientific Corporation

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT04200937·Enrolling By Invitation

MCJR Joint Replacement Clinical Outcomes Database

for Joint Replacement

1 location in Indianapolis

Sponsor: Midwest Center for Joint Replacement

Sex: All·Age: All ages

Code: NCT03328611·Recruiting

Apply to this trial

Measuring the Impact of Onco4D® Guidance on Chemotherapy Selection and Outcomes

for Cancer

1 location in Indianapolis

Sponsor: Animated Dynamics, Inc.

Sex: All·Age: All ages

Code: NCT04891952·Not Yet Recruiting

Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

for C3G

Drug: Iptacopan

13 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT04817618·Phase 3·Recruiting

Apply to this trial

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

Apply to this trial

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

for Prostate Cancer

20 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04787744·Phase 2, Phase 3·Recruiting

Apply to this trial

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

9 locations incl. Indianapolis

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting

Apply to this trial

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

Apply to this trial

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for Pancreatic Acinar Cell Carcinoma

452 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04858334·Phase 2·Recruiting

Apply to this trial

DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for Relapsed Diffuse Large B-cell Lymphoma

17 locations incl. Fountain Valley

Sponsor: ImmunoVaccine Technologies, Inc. (IMV Inc.)

Sex: All·Age: 18+

Code: NCT04920617·Phase 2·Recruiting

Apply to this trial

ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

53 locations incl. San Francisco

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting

Apply to this trial

Long Term Follow up of the LTOG Cohort

for Lung Transplant Failure and Rejection

10 locations incl. Birmingham

Sponsor: University of Pennsylvania

Sex: All·Age: 13+

Code: NCT04787822·Enrolling By Invitation

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

Apply to this trial

Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

18 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting

Apply to this trial

Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

for Breast Cancer

7 locations incl. Washington D.C.

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT04841148·Phase 2·Recruiting

Apply to this trial

Customized 3D Printed Oral Stents During Head and Neck Radiotherapy

for Head and Neck Carcinoma

7 locations incl. Phoenix

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT04870762·Phase 2·Recruiting

Apply to this trial

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

for Tibial Fractures

13 locations incl. Indianapolis

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 80

Code: NCT07006675·Phase 3·Recruiting

Apply to this trial

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

26 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting

Apply to this trial

External Nitric Oxide Measurement Through SNO Degradation

for Healthy

2 locations incl. Indianapolis

Sponsor: Indiana University

Sex: All·Age: 1 Day - 75·Accepts healthy volunteers

Code: NCT04903535·Enrolling By Invitation

Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT

for Post Operative Surgical Site Infection

31 locations incl. Redwood City

Sponsor: Major Extremity Trauma Research Consortium

Sex: All·Age: 18 - 64

Code: NCT04678154·Phase 3·Recruiting

Apply to this trial