Locomotor Recovery and Compensation Post-stroke (LRC)

Conditions

• Stroke

Eligibility Criteria

Sex

ALL

Age

18 Years - 85 Years

Healthy Volunteers

Not accepted

Interventions

• high-intensity training focused on stepping in variable contexts — BEHAVIORAL
  Approximately 10 weeks (\~30 sessions) of high-intensity training

Study Details

The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compensation should result in alternative predictive "rules' regarding how patients early post-stroke could recovery functional and neurological function.

Key Dates

Start date

Sep 1, 2021

Status verified

Mar 2026

Primary completion

Feb 28, 2028

Completion

Feb 28, 2028

Study Design

Enrollment

150 participants (estimated)

Allocation

NON_RANDOMIZED

Intervention model

SEQUENTIAL

Primary purpose

TREATMENT

Arms

• Other: Phase 1
  Observational evaluations for 6 months followed by 3-4 months of high-intensity training (HIT)
• Other: Phase 2
  Observational evaluations for 1 month followed by 3-4 months of high-intensity training (HIT)

Primary Outcome Measure

Gait speed [ Time Frame: 15 days post-stroke ]

Central Contacts

• Thomas G Hornby
  3173292353
  [email protected]
• Chris Henderson
  3173292353
  [email protected]

Locations (1)

Find similar trials in Indianapolis, IN

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