Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metricsfor Acute Pancreatitis13 locations incl. Los AngelesSponsor: Milton S. Hershey Medical CenterSex: All·Age: 18 - 75Code: NCT06401577·RecruitingApply to this trial
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancerfor Non-muscle Invasive Bladder Cancer With Carcinoma in SituDrug: Nadofaragene Firadenovec38 locations incl. TucsonSponsor: Ferring PharmaceuticalsSex: All·Age: 18+Code: NCT06545955·Phase 3·RecruitingApply to this trial
Post-Market Clinical Investigation of the IotaSOFT Insertion Systemfor Hearing Loss, Cochlear3 locations incl. IndianapolisSponsor: iotaMotion, Inc.Sex: All·Age: 12+Code: NCT06664697·RecruitingApply to this trial
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)for Treatment Resistant Depression24 locations incl. BirminghamSponsor: Abbott Medical DevicesSex: All·Age: 22 - 70Code: NCT06423430·RecruitingApply to this trial
Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resectionfor Colon Cancer1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18+Code: NCT06462521·Enrolling By Invitation
Denosumab for Type 1 Diabetesfor Type 1 Diabetes3 locations incl. BirminghamSponsor: City of Hope Medical CenterSex: All·Age: 18 - 50Code: NCT06524960·Phase 1, Phase 2·RecruitingApply to this trial
Large-Scale Implementation of a Decision Aid About Colorectal Cancer Screeningfor Colorectal Cancer Screening1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18+·Accepts healthy volunteersCode: NCT06597955·Enrolling By Invitation
ASSESS ALL ALS Studyfor Amyotrophic Lateral Sclerosis31 locations incl. BirminghamSponsor: St. Joseph's Hospital and Medical Center, PhoenixSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06578195·RecruitingApply to this trial
PREVENT ALL ALS Studyfor Amyotrophic Lateral Sclerosis31 locations incl. BirminghamSponsor: St. Joseph's Hospital and Medical Center, PhoenixSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06581861·RecruitingApply to this trial
Acoustic Waveform Respiratory Evaluationfor Asthma2 locations incl. IndianapolisSponsor: Indiana UniversitySex: All·Age: 8 - 70·Accepts healthy volunteersCode: NCT06512064·RecruitingApply to this trial
Fibrosis Lessens After Metabolic Surgeryfor Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD)4 locations incl. PhoenixSponsor: Ali AminianSex: All·Age: 18 - 75·Accepts healthy volunteersCode: NCT06374875·Phase 4·RecruitingApply to this trial
Trial of Naltrexone/Bupropion for the Treatment of Methamphetamine Use Disorderfor Methamphetamine-dependence11 locations incl. Little RockSponsor: National Institute on Drug Abuse (NIDA)Sex: All·Age: 18 - 65Code: NCT06233799·Phase 3·RecruitingApply to this trial
A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastomafor GlioblastomaDrug: Niraparib32 locations incl. BirminghamSponsor: Ivy Brain Tumor CenterSex: All·Age: 18+Code: NCT06388733·Phase 3·RecruitingApply to this trial
Health Outcomes of Parents With Cystic Fibrosis-Aim 2for Cystic Fibrosis18 locations incl. BirminghamSponsor: University of PittsburghSex: All·Age: 18+Code: NCT06296394·RecruitingApply to this trial
Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)for PSC11 locations incl. SacramentoSponsor: PSC Partners Seeking a CureSex: All·Age: 18 - 75Code: NCT06297993·RecruitingApply to this trial
AAA-SHAPE Pivotal Trial: Abdominal Aortic Aneurysm Sac Healing and Prevention of Expansionfor Aortic Aneurysm, Abdominal39 locations incl. BirminghamSponsor: Shape Memory Medical, Inc.Sex: All·Age: 18+Code: NCT06029660·RecruitingApply to this trial
The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registryfor Cesarean Delivery34 locations incl. Little RockSponsor: Yale UniversitySex: Female·Age: 15 - 55·Accepts healthy volunteersCode: NCT06030063·RecruitingApply to this trial
Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Studyfor Alzheimer Disease, Early Onset1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 40 - 75Code: NCT05573490·RecruitingApply to this trial
National Liver Cancer Screening Trialfor Carcinoma, Hepatocellular18 locations incl. Los AngelesSponsor: University of Texas Southwestern Medical CenterSex: All·Age: 18 - 85Code: NCT06084234·Phase 4·RecruitingApply to this trial
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)for Soft Tissue Sarcoma26 locations incl. PhoenixSponsor: Polaris GroupSex: All·Age: 18 - 99Code: NCT05712694·Phase 3·RecruitingApply to this trial
uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmytofor Urothelial Carcinoma22 locations incl. Santa MonicaSponsor: UroGen Pharma Ltd.Sex: All·Age: 18+Code: NCT05874921·RecruitingApply to this trial
Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapyfor Open tíbia Fracture29 locations incl. ChandlerSponsor: University of Maryland, BaltimoreSex: All·Age: 18+Code: NCT05615844·Phase 3·RecruitingApply to this trial
A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphomafor LymphomaDrug: Glofitamab18 locations incl. BerkeleySponsor: Hoffmann-La RocheSex: All·Age: 18+Code: NCT06084936·Phase 3·RecruitingApply to this trial
DAREON™-5: A Study to Test Whether Different Doses of BI 764532 Help People With Small Cell Lung Cancer or Other Neuroendocrine Cancersfor Small Cell Lung Carcinoma16 locations incl. MobileSponsor: Boehringer IngelheimSex: All·Age: 18+Code: NCT05882058·Phase 2·RecruitingApply to this trial
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Upfor Asthma2 locations incl. IndianapolisSponsor: Oregon Health and Science UniversitySex: All·Age: 6 - 16Code: NCT06106646·RecruitingApply to this trial
Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgeryfor Skull Base Neoplasms1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18+·Accepts healthy volunteersCode: NCT05898074·RecruitingApply to this trial
Study of Navtemadlin as Maintenance Therapy in TP53WT Advanced or Recurrent Endometrial Cancerfor Endometrial Cancer19 locations incl. VallejoSponsor: Kartos Therapeutics, Inc.Sex: Female·Age: 18+Code: NCT05797831·Phase 2, Phase 3·RecruitingApply to this trial
Alzheimer's Disease Neuroimaging Initiative 4for Mild Cognitive Impairment59 locations incl. BirminghamSponsor: University of Southern CaliforniaSex: All·Age: 55 - 90·Accepts healthy volunteersCode: NCT05617014·Enrolling By Invitation
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixationfor Infections13 locations incl. IndianapolisSponsor: Major Extremity Trauma Research ConsortiumSex: All·Age: 18+Code: NCT05699174·Phase 3·RecruitingApply to this trial
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Womenfor Heart Diseases42 locations incl. Los AngelesSponsor: Weill Medical College of Cornell UniversitySex: Female·Age: 18+Code: NCT04124120·RecruitingApply to this trial
Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)for Sickle Cell Trait10 locations incl. BirminghamSponsor: National Alliance for Sickle Cell CentersSex: All·Age: 18+·Accepts healthy volunteersCode: NCT06071377·RecruitingApply to this trial
Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trialfor Implementation Science1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18+·Accepts healthy volunteersCode: NCT05390411·Enrolling By Invitation
Delirium and Neuropsychological Recovery Among Emergency General Surgery Survivorsfor Delirium6 locations incl. RockfordSponsor: University of Wisconsin, MadisonSex: All·Age: 65+Code: NCT05373017·RecruitingApply to this trial
Alleviant ALLAY-HF Studyfor Heart Failure53 locations incl. BirminghamSponsor: Alleviant Medical, Inc.Sex: All·Age: 40+Code: NCT05685303·Enrolling By Invitation
Continuation of the nuMoM2b Heart Health Studyfor Cardiovascular Diseases14 locations incl. OrangeSponsor: RTI InternationalSex: Female·Age: 18+·Accepts healthy volunteersCode: NCT05472597·Enrolling By Invitation
The Diabetes Prevention Program Outcomes Study AD/ADRD Projectfor Diabetes27 locations incl. PhoenixSponsor: Marinella TemprosaSex: All·Age: All ages·Accepts healthy volunteersCode: NCT05704309·Enrolling By Invitation
Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Applicationfor Laryngeal Dystonia1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18 - 70Code: NCT05506085·RecruitingApply to this trial
Patient Satisfaction of Virtual vs In-Person Workup and Treatment of Lower Urinary Tract Symptoms.for Urologic Diseases1 location in IndianapolisSponsor: Indiana UniversitySex: All·Age: 18+·Accepts healthy volunteersCode: NCT05508165·RecruitingApply to this trial
Pediatric Dose Optimization for Seizures in Emergency Medical Servicesfor Seizures20 locations incl. TucsonSponsor: Stanford UniversitySex: All·Age: 6 Months - 13Code: NCT05121324·Phase 3·RecruitingApply to this trial
The Periviable GOALS Decision Support Toolfor Pregnancy Preterm12 locations incl. San DiegoSponsor: Indiana UniversitySex: All·Age: 18+Code: NCT05264779·RecruitingApply to this trial