Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
National Alliance for Sickle Cell Centers
Study ID
NCT06071377
Status
Recruiting
Apply to this trial

Conditions

  • Sickle Cell Trait

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Biologic Specimen Collection — OTHER
    Participants will have blood and urine collected at Baseline

Study Details

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.

Key Dates

Start date
Apr 1, 2023
Status verified
Nov 2025
Primary completion
Dec 31, 2026
Completion
Feb 28, 2027

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: Individuals with sickle cell trait

Primary Outcome Measure

Hemoglobin variant quantification [ Time Frame: Through study completion, an average of 2 years ]

Central Contacts

Locations (10)

FacilityCityStateZIPSite coordinators
University of AlabamaBirminghamAlabama35294
Marteesa William Oliver
[email protected]
Julie Kanter (PRINCIPAL_INVESTIGATOR)
Loma Linda University Health CareLoma LindaCalifornia92354
Monica Pizana
[email protected]
Akshat Jain (PRINCIPAL_INVESTIGATOR)
Nemours Children's HospitalWilmingtonDelaware19803
Nicole Wittmeyer
[email protected]
Robin Miller, MD (PRINCIPAL_INVESTIGATOR)
Indiana UniversityIndianapolisIndiana46202
Claire Kendrick
[email protected]
Andrew O'Brien (PRINCIPAL_INVESTIGATOR)
Functional FluidicsDetroitMichigan48202
Jennell White, PhD
[email protected]
Ifeoma Iwuagwu
[email protected]
Patrick Hines, MD (PRINCIPAL_INVESTIGATOR)
University of North CarolinaChapel HillNorth Carolina27599
David Wichlan
[email protected]
Patrick Ellison (PRINCIPAL_INVESTIGATOR)
Duke UniversityDurhamNorth Carolina27710
JJ Strouse, MD (PRINCIPAL_INVESTIGATOR)
East Carolina UniversityGreenvilleNorth Carolina27834
Beng Fuh (PRINCIPAL_INVESTIGATOR)
Nationwide Children's HospitalColumbusOhio43205
Tiffany Rosetti
[email protected]
Anthony Villella, MD (PRINCIPAL_INVESTIGATOR)
UT Health HoustonHoustonTexas77030
Amanda Gregg
[email protected]
Idowu Modupe, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Birmingham, AL

By research site
University of Alabama· Birmingham, ALLoma Linda University Health Care· Loma Linda, CANemours Children's Hospital· Wilmington, DEIndiana University· Indianapolis, INFunctional Fluidics· Detroit, MIUniversity of North Carolina· Chapel Hill, NC

Related Studies