Paid Clinical Trials in Illinois

Illinois has 2,953 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

2,953 clinical trials

↓ Download CSV

ARPA-H Smart Band-Aid to Measure Chronic Pain in Women

for Chronic Pain

2 locations incl. Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06994988·Not Yet Recruiting

Medical Management With Endovascular Thrombectomy Versus Medical Management Alone in Patients Presenting Beyond 24 Hours of Last Known Well

for Acute Ischemic Stroke

6 locations incl. Chicago

Sponsor: Amrou Sarraj

Sex: All·Age: 18 - 85

Code: NCT07115940·Recruiting

Apply to this trial

Cognitive-Motor Training for AD/ADRD Prevention

for MCI

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT07160582·Not Yet Recruiting

Mode of Ventilation During Critical Illness at Multiple Centers

for Respiratory Failure

4 locations incl. Chicago

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07313956·Enrolling By Invitation

Northwestern Neuromuscular Disease Biorepository

for Neuromuscular Diseases (NMD)

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07477509·Recruiting

Apply to this trial

Paracervical Block With Combined Ketorolac and Lidocaine for Osmotic Dilator Placement

for Pain Management

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: Female·Age: 18+

Code: NCT07487246·Phase 2·Not Yet Recruiting

Occlutech AFR Fontan Study

for Failure of Fontan Type Circulation

7 locations incl. Birmingham

Sponsor: Occlutech International AB

Sex: All·Age: All ages

Code: NCT07532369·Not Yet Recruiting

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Ascending Doses of ABBV-1451 Infusions and Injections in Healthy Adult Participants

for Healthy Volunteer

1 location in Grayslake

Sponsor: AbbVie

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07570147·Phase 1·Recruiting

Apply to this trial

PACU Discharge Readiness

for Patient Discharge

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07588542·Not Yet Recruiting

Trial in HPV Prevention for the U.S. Vietnamese Community

for HPV-related Cancers

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07637630·Recruiting

Apply to this trial

Geriatric Assessment and Technology Evaluation in Prostate Cancer

for Prostate Cancer

1 location in Chicago

Sponsor: University of Chicago

Sex: Male·Age: 18 Minutes+

Code: NCT06215508·Recruiting

Apply to this trial

Pivotal Trial to Evaluate the Safety and Effectiveness of the P&F TricValve® Transcatheter Bicaval Valve System

for Tricuspid Valve Disease

35 locations incl. Birmingham

Sponsor: P+F Products + Features USA Inc.

Sex: All·Age: 18 - 85

Code: NCT06458907·Not Yet Recruiting

Horizon Two: HR NDMM (MMRC-100)

for High Risk Newly Diagnosed Multiple Myeloma

7 locations incl. Atlanta

Sponsor: Multiple Myeloma Research Consortium

Sex: All·Age: 18+

Code: NCT07053436·Phase 2·Recruiting

Apply to this trial

Correlation Between an Impedance Cardiography Test for Decompensation and the Development of Left Ventricular Replacement Fibrosis

for Aortic Stenosis

1 location in Chicago

Sponsor: Dermed Diagnostics, Inc.

Sex: All·Age: 18+

Code: NCT07230964·Recruiting

Apply to this trial

A Study to Select a Dose Regimen (Part A) and to Investigate Overall Survival (Part B) With Nanvuranlat Compared With Physician's Best Choice in Participants Aged 18 Years or Older With Biliary Tract Cancer

for Advanced Biliary Tract Cancer

23 locations incl. Duarte

Sponsor: J-Pharma Co., Ltd.

Sex: All·Age: 18+

Code: NCT07265674·Phase 3·Recruiting

Apply to this trial

Study of Oral Food Challenge Biomarkers (SAFER)

for Allergy

10 locations incl. Little Rock

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 12 Months - 17

Code: NCT07279467·Not Yet Recruiting

A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

for Lung Neoplasm Malignant

2 locations incl. Clermont

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07286149·Phase 1, Phase 2·Recruiting

Apply to this trial

52-week Open Label Safety-Tolerability Study

for Schizophrenia

23 locations incl. Chandler

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07369154·Phase 3·Not Yet Recruiting

Study to Evaluate the Efficacy and Safety of BMN 333 Versus Vosoritide in Children With Achondroplasia

for Achondroplasia

Drug: Vosoritide

5 locations incl. Oakland

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 17

Code: NCT07441876·Phase 2, Phase 3·Recruiting

Apply to this trial

Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.

for Inguinal Hernia Bilateral

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07461558·Recruiting

Apply to this trial

Center for Research and Education on Aging and Technology Enhancement - CREATE V - Project 3

for Mild Cognitive Impairment

3 locations incl. Tallahassee

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07485725·Not Yet Recruiting

Combatting HIV Or Other STIs Early (CHOOSE)

for HIV

6 locations incl. San Francisco

Sponsor: Westat

Sex: Male·Age: 13 - 24·Accepts healthy volunteers

Code: NCT07510048·Phase 2·Not Yet Recruiting

Assessing Two Coenzyme Q10 Products in Men and Women

for CoQ10 Blood Levels

1 location in Addison

Sponsor: Midwest Center for Metabolic and Cardiovascular Research

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07530250·Not Yet Recruiting

Effects of Delay in Hearing Assistive Technology

for Audio Processing Delay

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07533071·Not Yet Recruiting

EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment

for Lennox Gastaut Syndrome (LGS)

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 2 - 35

Code: NCT07555171·Enrolling By Invitation

A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.

for Healthy Volunteers

1 location in Grayslake

Sponsor: AbbVie

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07567781·Phase 1·Recruiting

Apply to this trial

BOND: Direct Breastfeeding to Enhance Maternal and Infant Health in Congenital Heart Disease

for Congenital Heart Disease (CHD)

8 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582848·Not Yet Recruiting

Prenatally-initiated Psychological Intervention for Mothers of Infants With Congenital Heart Disease (CHD)

for Congenital Heart Disease (CHD)

17 locations incl. Phoenix

Sponsor: Carelon Research

Sex: All·Age: 18+

Code: NCT07582861·Not Yet Recruiting

Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies

for Ulcerative Colitis (UC)

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT07427017·Phase 2·Recruiting

Apply to this trial

Breakthrough - T1DM and Chronic Kidney Disease

for Diabete Type 1

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT07592000·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)

for Muscular Atrophy, Spinal

3 locations incl. Chicago

Sponsor: Biogen

Sex: All·Age: 0 Days - 42 Days

Code: NCT07221669·Phase 3·Recruiting

Apply to this trial

U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

for Bone Tumor

3 locations incl. San Diego

Sponsor: Precision IO Group

Sex: All·Age: 22+

Code: NCT07325578·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma

Drug: PF-08634404

57 locations incl. Aurora

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07392892·Phase 2, Phase 3·Recruiting

Apply to this trial

ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA

for Knee Osteoarthritis

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 40 - 85

Code: NCT07224958·Recruiting

Apply to this trial

Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS

for Kidney Stones

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07072598·Recruiting

Apply to this trial

Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

51 locations incl. Tucson

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting

Apply to this trial

Phase 2 Study to Assess the Safety and Efficacy of ANG003

for Exocrine Pancreatic Insufficiency (EPI)

26 locations incl. Long Beach

Sponsor: Anagram Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT07450547·Phase 2·Recruiting

Apply to this trial

PREcision MEDicine In Achalasia (PREMEDIA)

for Type I Achalasia

13 locations incl. Scottsdale

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293650·Phase 3·Recruiting

Apply to this trial

Effects of Transcutaneous Vagal Nerve Stimulation on Post-Surgical Return to Consciousness, Delirium, and Depression

for Post Operative Delirium

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07610655·Recruiting

Apply to this trial

AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

for Obesity

Drug: NNC0487-0111

13 locations incl. Anniston

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07503210·Phase 3·Recruiting

Apply to this trial