Assessing Two Coenzyme Q10 Products in Men and Women

Part of paid clinical trials in Addison, Illinois.

Sponsor
Midwest Center for Metabolic and Cardiovascular Research
Study ID
NCT07530250
Status
Not Yet Recruiting

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Conditions

  • CoQ10 Blood Levels

Eligibility Criteria

Sex
ALL
Age
21 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • high absorption CoQ10 product — DIETARY_SUPPLEMENT
    100 mg CoQ10 product designed for high absorption (administered as two 50 mg capsules)
  • standard CoQ10 product — DIETARY_SUPPLEMENT
    100 mg standard CoQ10 product (administered as two 50 mg capsules)

Study Details

The goal of this clinical trial is to compare the relative bioavailability of coenzyme Q10 (CoQ10) from acute administrations of a CoQ10 product designed for enhanced absorption versus a standard CoQ10 product in healthy men and women. Participants will be asked to come to the clinical on five different occasions, including a screening visit (visit 1, -7 days), two test 1 visits (visits 2 and 3, days 0 and 1), and two test 2 visits (visits 4 and 5, days 7 and 8). During the start of each test visit (visits 2 and 4), the participant will consume each study product with water and a standardized breakfast meal. Then, blood samples will be collected over a 10-hour period, and a standardized lunch, dinner, and snacks will be provided. The participant will return to the clinic the next morning for a blood draw 24 hours after the study product ingestion from the previous day. The same procedures will be repeated 7 to 14 days later with the other study product.

Key Dates

Start date
Apr 30, 2026
Status verified
May 2026
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Experimental: Experimental - high absorption CoQ10 product
    100 mg CoQ10 product designed for high absorption (administered as two 50 mg capsules)
  • Active Comparator: Active Comparator - standard CoQ10 product
    100 mg standard CoQ10 product (administered as two 50 mg capsules)

Primary Outcome Measure

Net incremental area under the curve (niAUC) for plasma CoQ10 [ Time Frame: 7 to 14 days between conditions ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Biofortis Clinical ResearchAddisonIllinois60101
Gina Castiglione-Berg
6306172000

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