Cardiology Clinical Trials in Houston, TX

As of June 2026, 78 paid clinical trials are recruiting for Cardiology in Houston, Texas. Cardiology trials investigate SGLT-2 inhibitors, myosin modulators, lipid-lowering therapies, anti-inflammatory agents, and device-based interventions across heart failure, hypertension, AFib, and coronary artery disease. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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78 clinical trials for Cardiology

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PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

47 locations incl. Phoenix

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting

Apply to this trial

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure

31 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40 - 85

Code: NCT06122779·Phase 2·Recruiting

Apply to this trial

Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism

for Trauma Injury

4 locations incl. Aurora

Sponsor: Bryan Cotton

Sex: All·Age: 18+

Code: NCT05794165·Phase 2·Enrolling By Invitation

Left vs Left Randomized Clinical Trial

for Heart Failure

57 locations incl. Gilbert

Sponsor: Baylor College of Medicine

Sex: All·Age: 18+

Code: NCT05650658·Recruiting

Apply to this trial

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

47 locations incl. Phoenix

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting

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The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

for Coronary Artery Disease

9 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05618353·Phase 4·Recruiting

Apply to this trial

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

for Heart Failure

20 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 29 Days - 17

Code: NCT05714085·Phase 2, Phase 3·Recruiting

Apply to this trial

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

for Heart Failure

Drug: Ziltivekimab

184 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT05636176·Phase 3·Recruiting

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

42 locations incl. Los Angeles

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting

Apply to this trial

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

for Dyslipidemias

Drug: Bempedoic acid

3 locations incl. Los Angeles

Sponsor: Priscilla Hsue, MD

Sex: All·Age: 40+

Code: NCT05488431·Phase 2·Recruiting

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

150 locations incl. Birmingham

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting

Apply to this trial

EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study

for Heart Failure

15 locations incl. Los Angeles

Sponsor: Berlin Heart, Inc

Sex: All·Age: Up to 21

Code: NCT05610787·Enrolling By Invitation

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

for Heart Failure

12 locations incl. La Jolla

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18 - 100

Code: NCT06425848·Recruiting

Apply to this trial

The CONFORM Pivotal Trial

for Atrial Fibrillation

76 locations incl. Birmingham

Sponsor: Conformal Medical, Inc

Sex: All·Age: 18+

Code: NCT05147792·Recruiting

Apply to this trial

SELUTION4BTK Trial

for Peripheral Arterial Disease

30 locations incl. Chandler

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05055297·Recruiting

Apply to this trial

Assessment of CCM in HF With Higher Ejection Fraction

for Heart Failure

105 locations incl. Birmingham

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT05064709·Recruiting

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Vascular Events In Patients Undergoing Same-day Noncardiac Surgery (VALIANCE) Study

for Preoperative Care

5 locations incl. Winston-Salem

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 45+

Code: NCT04973397·Recruiting

Apply to this trial

Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs

for Interstitial Lung Disease

14 locations incl. Phoenix

Sponsor: Paragonix Technologies

Sex: All·Age: All ages

Code: NCT04930289·Enrolling By Invitation

The GUARDIAN Trial

for Blood Pressure

6 locations incl. Omaha

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 45+

Code: NCT04884802·Recruiting

Apply to this trial

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

27 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting

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Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

for Aortic Stenosis

55 locations incl. Huntsville

Sponsor: University of British Columbia

Sex: All·Age: All ages

Code: NCT04634240·Recruiting

Apply to this trial

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

for Cardiomyopathy

1 location in Houston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18 - 80

Code: NCT02962661·Phase 1·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

51 locations incl. Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

for Stroke

2 locations incl. Los Angeles

Sponsor: Population Health Research Institute

Sex: All·Age: 55+

Code: NCT03968393·Phase 4·Recruiting

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ATrial Tachycardia PAcing Therapy in Congenital Heart

for Atrial Arrhythmia

14 locations incl. Los Angeles

Sponsor: Ian Law

Sex: All·Age: All ages

Code: NCT03209583·Recruiting

Apply to this trial

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

75 locations incl. Gilbert

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting

Apply to this trial

Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

52 locations incl. Phoenix

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting

Apply to this trial

Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

for Pulmonary Vascular Disease

13 locations incl. Palo Alto

Sponsor: New York Medical College

Sex: All·Age: 1 Day - 21

Code: NCT02249923·Recruiting

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Tracking Results of Ablations to Combat AF Registry Generation 2

for Atrial Fibrillation

26 locations incl. Huntsville

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT05111015·Recruiting

Apply to this trial

Product Surveillance Registry

for Cardiac Rhythm Disorders

134 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT01524276·Recruiting

Apply to this trial

DeBakey Cardiovascular Magnetic Resonance Study

for Cardiovascular Diseases

1 location in Houston

Sponsor: Dipan Shah

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04281823·Recruiting

Apply to this trial

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

for Heart

3 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 20 - 90

Code: NCT01258231·Recruiting

Apply to this trial

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

for Arrhythmia

113 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT00271180·Recruiting

Apply to this trial

Conditions in Cardiology (Houston, TX)

Heart failure· 31 Cardiovascular disease (general)· 15 Hypertension (high blood pressure)· 11 Atrial fibrillation· 10 Pulmonary hypertension· 9 Coronary artery disease· 6 Peripheral artery disease· 4 Congenital heart disease· 3 Myocardial infarction (heart attack)· 2 Venous thromboembolism· 1