Paid Clinical Trials in Gainesville, FL

As of June 2026, 599 paid clinical trials are recruiting in Gainesville, Florida. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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599 clinical trials

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The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma

for Trauma Injury

3 locations incl. Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 100

Code: NCT06606119·Recruiting

Apply to this trial

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

66 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting

Apply to this trial

Spinal Networks of Balance Learning and Retention in Older Adults

for Aging

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 65 - 95·Accepts healthy volunteers

Code: NCT06517043·Recruiting

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A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

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A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

for Colorectal Cancer

44 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06562543·Phase 4·Recruiting

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HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

for Degenerative Disc Disease (DDD)

13 locations incl. Birmingham

Sponsor: ReGelTec, Inc.

Sex: All·Age: 22 - 85

Code: NCT06011551·Recruiting

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Antihypertensive Mechanisms of Minocycline in Resistant Hypertension

for Hypertension, Resistant to Conventional Therapy

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 100

Code: NCT06246396·Phase 4·Recruiting

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Use of CBD in the Treatment of Anxiety

for Anxiety

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 55

Code: NCT06672666·Phase 2·Recruiting

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Modernizing Instructions to Improve Treatment Participation of Subjects During Their First Radiotherapy

for Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT06246409·Recruiting

Apply to this trial

Perspectives on Spinal Manipulative Therapy for Low Back Pain

for Low Back Pain

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 70

Code: NCT06590116·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Drug: Amivantamab

150 locations incl. Daphne

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06667076·Phase 2·Recruiting

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting

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A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own Doctors

for Friedreich Ataxia

4 locations incl. Los Angeles

Sponsor: Biogen

Sex: All·Age: 16+

Code: NCT06623890·Recruiting

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OPTIMUS PRIME: Safety and Feasibility of OPTune GIO® Integrated With MRI-gUided Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa, A randomizEd Trial

for Recurrent Glioblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 90

Code: NCT06558214·Phase 2·Recruiting

Apply to this trial

ReMARK: Addressing Disparities in Rural HPV-related Cancer Prevention

for Papillomavirus Vaccines

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 8 - 99

Code: NCT06535139·Recruiting

Apply to this trial

Listening to Calming Music

for Music

2 locations incl. Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06710886·Recruiting

Apply to this trial

AD HOC Trial: Artificial Intelligence-Based Drug Dosing In Hepatocellular Carcinoma

for Hepatocellular Carcinoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT05669339·Phase 2·Recruiting

Apply to this trial

RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)

for Recurrent Glioblastoma

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT06389591·Phase 1·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Non-squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

77 locations incl. Mobile

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

37 locations incl. Dothan

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06690398·Phase 3·Recruiting

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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

for Resistant Hypertension

5 locations incl. Orange

Sponsor: DeepQure Inc.

Sex: All·Age: 22 - 80

Code: NCT06526858·Recruiting

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A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

61 locations incl. Avondale

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting

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A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

for Neovascular Age-related Macular Degeneration

18 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 50 - 90

Code: NCT06660667·Phase 1, Phase 2·Recruiting

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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

30 locations incl. Birmingham

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06701903·Phase 2·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

74 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting

Apply to this trial

Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction

for Breast Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: Female·Age: 18 - 80

Code: NCT06461650·Recruiting

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Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

for Sepsis, Septic Shock

5 locations incl. Gainesville

Sponsor: Bluejay Diagnostics, Inc.

Sex: All·Age: 22+

Code: NCT06654895·Recruiting

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A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT)

for Hereditary Hemorrhagic Telangiectasia

8 locations incl. Birmingham

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06659640·Phase 1, Phase 2·Recruiting

Apply to this trial

Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder Cancer

for Bladder Cancer

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT06488222·Phase 2·Recruiting

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Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult Participants

for Breast Reconstruction

22 locations incl. Los Angeles

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06575192·Phase 3·Recruiting

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A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

for Systemic Sclerosis

15 locations incl. Orange

Sponsor: Nkarta, Inc.

Sex: All·Age: 18 - 75

Code: NCT06733935·Phase 1, Phase 2·Recruiting

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Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)

for Gastrointestinal Cancer

13 locations incl. Santa Monica

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06596694·Phase 1, Phase 2·Recruiting

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Combining a Smartphone App With Medications to Manage Heavy Drinking

for Alcohol Use Disorder (AUD)

15 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06303778·Recruiting

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Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

for Neuroblastoma

20 locations incl. Birmingham

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: Up to 30

Code: NCT06541262·Phase 1, Phase 2·Recruiting

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Evaluation and Modification of Surgeon Ergonomics in the Operation Room Using Artificial Intelligence Analytics

for Work Related Upper Limb Disorder

2 locations incl. Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 99

Code: NCT06576570·Enrolling By Invitation

Open-Label Extension Study of Setmelanotide

for Obesity Associated With Defects in Leptin-melanocortin Pathway

13 locations incl. Scottsdale

Sponsor: Rhythm Pharmaceuticals, Inc.

Sex: All·Age: 2+

Code: NCT06596135·Phase 3·Enrolling By Invitation

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

for Long COVID

Drug: Baricitinib

17 locations incl. Tucson

Sponsor: Wes Ely

Sex: All·Age: 18+

Code: NCT06631287·Phase 3·Recruiting

Apply to this trial

Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics

for Acute Pancreatitis

13 locations incl. Los Angeles

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 75

Code: NCT06401577·Recruiting

Apply to this trial