As of June 2026, 1,346 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Cleveland offers studies at sites including Cleveland Clinic for conditions such as Heart Failure, Breast Cancer, Advanced Solid Tumor, Acute Myeloid Leukemia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Cleveland has approximately 1,346 recruiting research studies across a wide range of therapeutic areas. Ohio is home to The Ohio State University Wexner Medical Center, Cleveland Clinic, Cincinnati Children's, and University Hospitals Cleveland Medical Center — collectively running clinical trials across every major therapeutic area.
Researchers run research studies in Cleveland, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cleveland Clinic | Heart Failure, Cardiovascular Diseases, Atrial Fibrillation | 374 |
| Cleveland Clinic Foundation | Acute Myeloid Leukemia, COPD, Heart Failure | 160 |
| University Hospitals Cleveland Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 157 |
| Case Western Reserve University | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Recurrent Endometrial Carcinoma | 85 |
| MetroHealth Medical Center | Spinal Cord Injuries, Spinal Cord Injury Cervical, Stroke | 41 |
| The Cleveland Clinic Foundation | Mitral Regurgitation, Adrenalectomy, Advanced Solid Tumor | 28 |
| Rainbow Babies and Childrens Hospital | B Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Down Syndrome | 25 |
| Louis Stokes VA Medical Center, Cleveland, OH | Parkinson's Disease, Spinal Cord Injury, Atherosclerosis | 24 |
| Cleveland Clinic Main Campus | Blood Pressure, Breast Cancer, Abdominal Wall Hernia | 23 |
| The Cleveland Clinic | Depression / Major Depressive Disorder, Glioblastoma, Hopelessness | 18 |
| Cleveland Clinic Cancer Center/Fairview Hospital | Anatomic Stage IV Breast Cancer AJCC v8, Ovarian Carcinoma, Prostate Adenocarcinoma | 17 |
| University Hospitals | Acute Kidney Injury, B Cell Lymphoma, Bladder Pain Syndrome | 14 |
| Cleveland Clinic Taussig Cancer Center | Glioma, Advanced Solid Tumor, Advanced Systemic Mastocytosis (AdvSM) | 11 |
| UH Cleveland Medical Center | Breast Cancer, Acute Decompensated Heart Failure, Atrial Fibrillation | 11 |
| University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Pancreatic Cancer, Acute Lymphatic Leukemia, Acute Myelogenous Leukemia | 11 |
| Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center | Acute Myeloid Leukemia, Cyst of Pancreas, Cytokine Release Syndrome | 11 |
| University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center | Acute Lymphocytic Leukemia, Brain Metastases, Brain Necrosis | 10 |
| MetroHealth | Acute Kidney Injury, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 9 |
| The MetroHealth System | AV Block, COVID-19, Cardiovascular Diseases | 9 |
| University Hospitals of Cleveland | Advanced Solid Tumors, Aortic Aneurysm, Aortic Dissection | 9 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute | Amyloid Light-chain Amyloidosis, B-cell Non Hodgkin Lymphoma, Basal Cell Carcinoma | 8 |
| Cleveland Clinic Children's | Heart Failure (Pediatric), Left Ventricular Systolic Dysfunction, Neuroblastoma | 8 |
| University Hospitals Cleveland | Abdominal Aortic Aneurysm, Ascending Aorta Aneurysm, Ascending Aortic Aneurysm Enlargement | 8 |
| Cleveland Clinic Fairview Hospital | Blood Pressure, HPV Infection, Pre-Cancerous Dysplasia | 7 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation | Head and Neck Cancer, Oral Cancer, Cancer | 6 |
Recruiting trials in Cleveland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Clinical trials in Ohio are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Ohio research additionally follows state public health department oversight and any applicable state privacy statutes.
Hipa.ai aggregates every recruiting study in Cleveland from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
There are approximately 1,346 recruiting clinical trials in Cleveland, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Cleveland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Cleveland include Heart Failure (24), Breast Cancer (21), Advanced Solid Tumor (17), Acute Myeloid Leukemia (16), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cleveland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Cleveland include Cleveland Clinic, Cleveland Clinic Foundation, University Hospitals Cleveland Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Cleveland are Cancer & tumors (410), Neurology & pain (94), Cardiovascular (94). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.