Oncology Clinical Trials in Charlottesville, VA

As of June 2026, 124 paid clinical trials are recruiting for Oncology in Charlottesville, Virginia. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

124 clinical trials for Oncology

·Clear filters·↓ Download CSV

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for Advanced Malignant Solid Neoplasm

36 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05327010·Phase 2·Recruiting

Apply to this trial

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

67 locations incl. Gilbert

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05552222·Phase 3·Recruiting

Apply to this trial

Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

20 locations incl. Birmingham

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting

Apply to this trial

Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002)

for Myelofibrosis

2 locations incl. Philadelphia

Sponsor: Karen Ballen, MD

Sex: All·Age: 18 - 75

Code: NCT05233618·Phase 1·Recruiting

Apply to this trial

Adjuvant Chemoradiation and Biomarkers of Response in High-risk Breast Cancer

for Breast Cancer

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT05288777·Phase 2, Phase 3·Recruiting

Apply to this trial

GEMINI-NSCLC: NSCLC Biomarker Study

for Non-Small Cell Lung Cancer

58 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT05236114·Recruiting

Apply to this trial

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

164 locations incl. Birmingham

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting

Apply to this trial

Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

219 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting

Apply to this trial

A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

134 locations incl. Goodyear

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting

Apply to this trial

Cardioprotection in AML

for AML

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18+

Code: NCT04977180·Phase 2·Recruiting

Apply to this trial

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

for Leukemia, Myeloid, Acute

33 locations incl. Newport Beach

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 12+

Code: NCT04988555·Phase 1, Phase 2·Recruiting

Apply to this trial

Focused Ultrasound and Gemcitabine in Breast Cancer

for Breast Cancer

1 location in Charlottesville

Sponsor: Patrick Dillon, MD

Sex: All·Age: 18+

Code: NCT04796220·Phase 1·Recruiting

Apply to this trial

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

for Renal Cell Carcinoma (RCC)

46 locations incl. Phoenix

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT05176483·Phase 1·Recruiting

Apply to this trial

Using Aspirin to Improve Immunological Features of Ovarian Tumors

for Ovarian Cancer

4 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Female·Age: 18+

Code: NCT05080946·EARLY_Phase 1·Recruiting

Apply to this trial

A Study of NX-1607 in Adults With Advanced Malignancies

for Ovarian Cancer, Epithelial

10 locations incl. Duarte

Sponsor: Nurix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05107674·Phase 1·Recruiting

Apply to this trial

A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for Prostate Cancer

24 locations incl. Tucson

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT04729114·Phase 1·Recruiting

Apply to this trial

Study of Lunresertib Alone or in Combination With RP-3500 or Debio 0123 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

17 locations incl. Los Angeles

Sponsor: Debiopharm International SA

Sex: All·Age: 12+

Code: NCT04855656·Phase 1·Recruiting

Apply to this trial

4D-MRI for Precision Medicine

for Healthy Volunteers

1 location in Charlottesville

Sponsor: University of Virginia

Sex: All·Age: 18 - 82·Accepts healthy volunteers

Code: NCT04657042·Recruiting

Apply to this trial

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

Apply to this trial

Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

45 locations incl. Phoenix

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting

Apply to this trial

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

Apply to this trial

A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

24 locations incl. Tucson

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting

Apply to this trial

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1150 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

Apply to this trial

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

32 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting

Apply to this trial

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

Apply to this trial

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for Advanced Solid Tumor

Drug: Tulmimetostat

17 locations incl. Atlanta

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04104776·Phase 1, Phase 2·Recruiting

Apply to this trial

Pan Tumor Rollover Study

for Cancer

59 locations incl. Huntsville

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting

Apply to this trial

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for Glioblastoma

42 locations incl. Birmingham

Sponsor: Global Coalition for Adaptive Research

Sex: All·Age: 18+

Code: NCT03970447·Phase 2, Phase 3·Recruiting

Apply to this trial

Vaginal Cuff Brachytherapy Fractionation Study

for Endometrial Cancer

3 locations incl. Baltimore

Sponsor: Kara Romano, MD

Sex: Female·Age: 18+

Code: NCT03785288·Phase 3·Recruiting

Apply to this trial

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Venetoclax

4 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03523975·Phase 1, Phase 2·Recruiting

Apply to this trial

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

Apply to this trial

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

for Ewing Sarcoma

23 locations incl. Scottsdale

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 12 - 85

Code: NCT03715933·Phase 1·Recruiting

Apply to this trial

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

Apply to this trial

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

Apply to this trial

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

67 locations incl. Birmingham

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

Apply to this trial

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

for Glioblastoma

12 locations incl. Birmingham

Sponsor: Patrick Wen, MD

Sex: All·Age: 18+

Code: NCT02977780·Phase 2·Recruiting

Apply to this trial

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

676 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting

Apply to this trial

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

245 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting

Apply to this trial

Conditions in Oncology (Charlottesville, VA)

Non-small cell lung cancer (NSCLC)· 16 Solid tumor· 15 Acute myeloid leukemia (AML)· 12 Breast cancer· 11 Metastatic prostate cancer· 8 Ovarian cancer· 8 Prostate cancer· 7 Myelodysplastic syndromes (MDS)· 7 Cancer (any)· 7 Endometrial cancer· 6 Pancreatic cancer· 5 Glioblastoma· 5 Multiple myeloma· 5 Leukemia (other)· 5 Diffuse large B-cell lymphoma (DLBCL)· 5 Colorectal cancer· 4 Biliary tract cancer· 4 Bladder cancer· 4 Cervical cancer· 4 Myelofibrosis· 4 Non-Hodgkin lymphoma· 4 Mantle cell lymphoma· 4 Melanoma· 4 Head and neck cancer· 4 Lung cancer· 3 Small cell lung cancer· 3 Hematologic malignancy· 3 Triple-negative breast cancer· 2 Gastric cancer· 2 Fallopian tube cancer· 2 Glioma· 2 Chronic lymphocytic leukemia (CLL)· 2 Myeloproliferative neoplasm· 2 Follicular lymphoma· 2 Small lymphocytic lymphoma· 2 Neuroendocrine tumors· 2 HER2-negative breast cancer· 1 Gastroesophageal junction cancer· 1 Liver cancer· 1 Brain cancer· 1 Chronic myelomonocytic leukemia· 1 Acute lymphoblastic leukemia· 1 Hodgkin lymphoma· 1 Marginal zone lymphoma· 1 Osteosarcoma· 1 Ewing sarcoma· 1 Neuroblastoma· 1