Paid Clinical Trials in California

California has 6,520 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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6,520 clinical trials

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

23 locations incl. Tucson

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting

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Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

for NSCLC (Non-small Cell Lung Cancer)

Drug: daraxonrasib

39 locations incl. Birmingham

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06881784·Phase 3·Recruiting

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Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Drug: Rilvegostomig

35 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06921785·Phase 3·Recruiting

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A Study of TAK-360 in Adults With Narcolepsy Without Cataplexy (NT2)

for Narcolepsy Type 2

31 locations incl. Auburn

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06952699·Phase 2·Recruiting

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Evaluating a Our Practice Advisory (OPA) to Optimize Hemoglobin A1c (A1c) and Thyroid-Stimulating Hormone (TSH) Test Orders

for Physician Workflow

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: All ages

Code: NCT06993805·Recruiting

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Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

48 locations incl. Birmingham

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting

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Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

6 locations incl. Scottsdale

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting

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Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

for Metastatic Urothelial Carcinoma

11 locations incl. Duarte

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06439836·Phase 1·Recruiting

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Treatment of Moderate to Severe Refractory Crohn's Disease

for Crohns Disease

13 locations incl. Scottsdale

Sponsor: Tr1X, Inc.

Sex: All·Age: 18 - 65

Code: NCT06721962·Phase 1, Phase 2·Recruiting

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A Study to Prevent Infantile Spasms Relapse

for Infantile Spasms

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 2 Months - 18 Months

Code: NCT06819670·Phase 2·Recruiting

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Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

2 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06910761·Phase 2·Recruiting

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A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee

for Knee Injuries

1 location in La Mesa

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 21 - 75

Code: NCT06916728·Enrolling By Invitation

WISPer: Evaluation of MTX-463 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

26 locations incl. Birmingham

Sponsor: Mediar Therapeutics

Sex: All·Age: 40+

Code: NCT06967805·Phase 2·Recruiting

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Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

for T-cell-prolymphocytic Leukemia

Drug: Venetoclax

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06810778·Phase 1, Phase 2·Recruiting

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Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118

for Psoriasis

3 locations incl. Anaheim

Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06846710·Phase 1·Recruiting

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A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

for Advanced Lung Cancer

16 locations incl. Phoenix

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06892548·Phase 1, Phase 2·Recruiting

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Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers

for Uric Acid Stones

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18 - 80

Code: NCT06335537·Phase 1·Recruiting

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PO Methadone Ortho Outpatient

for Arthroscopic Knee Repair

1 location in Los Angeles

Sponsor: Keck School of Medicine of USC

Sex: All·Age: 18+

Code: NCT06351215·Phase 3·Not Yet Recruiting

CGM Academy for Youth With Type 1 Diabetes

for Type1 Diabetes

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 8 - 18

Code: NCT06408207·Recruiting

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A Study of Lorigerlimab in Participants With Advanced Solid Tumors

for Platinum-resistant Ovarian Cancer

7 locations incl. Los Angeles

Sponsor: MacroGenics

Sex: Female·Age: 18+

Code: NCT06730347·Phase 2·Recruiting

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Nutrition OUtReach In Systems of Healthcare

for ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION

4 locations incl. Stanford

Sponsor: University of Kansas Medical Center

Sex: All·Age: 8 - 80

Code: NCT06802406·Recruiting

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Sleep TMS for Depression

for Major Depression

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 65

Code: NCT06824415·Recruiting

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Implementation Strategies for Self-Measured Blood Pressure Monitoring in Racially and Ethnically Diverse Populations

for Blood Pressure Monitoring, Home

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06871462·Enrolling By Invitation

SPYRAL GEMINI Pilot Study

for Hypertension

11 locations incl. Stanford

Sponsor: Medtronic Vascular

Sex: All·Age: 18 - 80

Code: NCT06907147·Recruiting

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Comparison of New SUREcore Biopsy of Needle to Standard of Care During Transperineal Prostate Biopsies

for Prostate Cancer

1 location in Sacramento

Sponsor: University of California, Davis

Sex: Male·Age: 18+

Code: NCT06907446·Recruiting

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A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.

for Systemic Lupus Erythematosus

7 locations incl. Anniston

Sponsor: AstraZeneca

Sex: All·Age: 18 - 70

Code: NCT06916806·Phase 1·Recruiting

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1550nm Non-ablative Fractional Vs 1927nm Thulium Fractional Laser for the Treatment of Female Pattern Hair Loss

for Female Pattern Baldness

1 location in San Diego

Sponsor: Goldman, Butterwick, Fitzpatrick and Groff

Sex: Female·Age: 35 - 65·Accepts healthy volunteers

Code: NCT06926023·Not Yet Recruiting

Multi-center Trial of Ferric Derisomaltose Versus no Intravenous Iron in Iron-deficient Subjects With Symptomatic Chronic Heart Failure

for Chronic Heart Failure

1 location in Pasadena

Sponsor: Pharmacosmos A/S

Sex: All·Age: 18+

Code: NCT06929806·Phase 3·Recruiting

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Integrating Metabolic and Vascular Sensors to Monitor Cardiometabolic Disorders After Nutrition Interventions

for NAFLD (Nonalcoholic Fatty Liver Disease)

1 location in Los Angeles

Sponsor: VA Greater Los Angeles Healthcare System

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06932289·Not Yet Recruiting

Motiva Implants® Post-Approval Study

for Breast Implant

30 locations incl. Beverly Hills

Sponsor: Motiva USA LLC

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06938399·Recruiting

Apply to this trial

Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

for Kidney Calculi

20 locations incl. Phoenix

Sponsor: Avvio Medical

Sex: All·Age: 21+

Code: NCT06942949·Recruiting

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SWIR Otoscopy Study

for Otitis Media

2 locations incl. Palo Alto

Sponsor: Stanford University

Sex: All·Age: 1 - 17

Code: NCT06944795·Not Yet Recruiting

A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

for Solid Tumor

11 locations incl. San Francisco

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06952010·Phase 1·Recruiting

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Epilepsy Cycles Longitudinal Monitoring to Inform Personalized Seizure-risk Estimation (ECLIPSE)

for Epilepsy (Treatment Refractory)

1 location in San Francisco

Sponsor: Insel Gruppe AG, University Hospital Bern

Sex: All·Age: 18+

Code: NCT06952764·Enrolling By Invitation

Ostomy Readmission Reduction Program

for Ostomy - Ileostomy or Colostomy

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT06956274·Not Yet Recruiting

Age-dependent Effects of Smoked and Oral Delta-9-THC

for Pain

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05865470·Phase 1·Recruiting

Apply to this trial

Understanding Participation Habits Among Plaque Psoriasis Patients

for Plaque Psoriasis

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT06338358·Not Yet Recruiting

Examining Engagement Trends Among Participants in Peripheral Neuropathy Clinical Research

for Peripheral Neuropathy

1 location in San Francisco

Sponsor: Power Life Sciences Inc.

Sex: All·Age: 18+

Code: NCT06338384·Not Yet Recruiting

NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver Disease

for Positron Emission Tomography

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06453915·EARLY_Phase 1·Recruiting

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Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)

for Major Depressive Disorder \(MDD

1 location in San Diego

Sponsor: Neurovalens Ltd.

Sex: All·Age: 18 - 80

Code: NCT06470035·Not Yet Recruiting