Paid Clinical Trials in California

California has 6,520 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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6,520 clinical trials

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

13 locations incl. Los Angeles

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting

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Clinical Study to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase, Non-surgical Standard of Care, in Patients With Venous Leg Ulcers

for Venus Leg Ulcers

1 location in Carlsbad

Sponsor: MediWound Ltd

Sex: All·Age: 18+

Code: NCT06690177·Phase 2·Not Yet Recruiting

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

for Atherosclerotic Cardiovascular Disease (ASCVD)

Drug: Inclisiran

36 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT06813911·Phase 3·Recruiting

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

for Neoplasms

6 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06884618·Phase 1·Recruiting

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Population Health Management for KPNC Members With Newly Diagnosed Diabetes: A Randomized Trial of a Proactive and Augmented Initial Care Strategy

for Type 2 Diabetes

1 location in Pleasanton

Sponsor: Kaiser Permanente

Sex: All·Age: 18 - 74

Code: NCT06906653·Enrolling By Invitation

Viral Specific T-Lymphocytes to Treat Infection With Adenovirus, Cytomegalovirus or Epstein-Barr Virus in Patients With Compromised Immunity

for Adenovirus

3 locations incl. Palo Alto

Sponsor: Jessie L. Alexander

Sex: All·Age: 1 Month - 65

Code: NCT06909110·Phase 1, Phase 2·Recruiting

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An 8-week Open-label Study of an Accelerated and Slower Switching to Xanomeline/Trospium Following Atypical Antipsychotic Treatment in Participants With Schizophrenia

for Schizophrenia Disorders

7 locations incl. Bellflower

Sponsor: Collaborative Neuroscience Research, LLC

Sex: All·Age: 18 - 65

Code: NCT06924255·Phase 4·Not Yet Recruiting

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

for Triple Negative Breast Cancer

9 locations incl. Los Angeles

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06926920·Phase 1, Phase 2·Recruiting

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Research and Engagement on Substance Use: Harnessing Awareness and Personalized Education (RESHAPE) to Improve Well-being and Self-efficacy

for Substance Use Disorder (SUD)

1 location in San Mateo

Sponsor: Evidation Health

Sex: All·Age: 21+

Code: NCT06952491·Enrolling By Invitation

Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for Soft-tissue Sarcoma

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07064018·Phase 1, Phase 2·Recruiting

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DoD AtMS for Posttraumatic Peripheral Neuropathic Pain

for Posttraumatic Peripheral Neuropathic Pain

1 location in San Diego

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18+

Code: NCT07301177·Recruiting

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Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

for Metastatic Castration-Resistant Prostate Carcinoma

3 locations incl. San Francisco

Sponsor: University of Washington

Sex: Male·Age: 18+

Code: NCT06526299·Phase 2·Recruiting

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A Study of Ranolazine in ALS

for Amyotrophic Lateral Sclerosis

6 locations incl. San Francisco

Sponsor: Swathy Chandrashekhar, MBBS

Sex: All·Age: 18+

Code: NCT06527222·Phase 2·Recruiting

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A Study of HyQvia in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) in Routine Clinical Care

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

9 locations incl. Rancho Mirage

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06538064·Recruiting

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

49 locations incl. Huntsville

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting

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Study for AZD4360 in Participants With Advanced Solid Tumours

for Gastric Cancer

3 locations incl. Santa Monica

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06921928·Phase 1, Phase 2·Recruiting

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Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

for AML, Adult

11 locations incl. Duarte

Sponsor: Stelexis BioSciences

Sex: All·Age: 18+

Code: NCT06533761·Phase 1·Recruiting

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A Study Evaluating the Safety and Efficacy of Glofitamab + Gemcitabine + Oxaliplatin in U.S. Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Lymphoma

Drug: Glofitamab

16 locations incl. La Jolla

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06624085·Phase 1·Recruiting

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A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease.

for Chagas Disease

4 locations incl. Sylmar

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 60

Code: NCT06632600·Phase 2·Recruiting

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Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

for Adolescent Drinking

2 locations incl. Commerce

Sponsor: RAND

Sex: All·Age: 12 - 19·Accepts healthy volunteers

Code: NCT06699251·Recruiting

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Preoperative Fasting vs. Not Fasting in Critically Ill Patients

for Critical Illness

19 locations incl. Palo Alto

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06751043·Recruiting

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Safely Optimizing Body Weight With TCMCB07 in Patients With Newly Diagnosed Colorectal Cancer Undergoing Chemotherapy

for Cancer Weight Loss

25 locations incl. Tucson

Sponsor: Endevica Bio

Sex: All·Age: 18+

Code: NCT06937177·Phase 2·Recruiting

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Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

for Small Cell Lung Cancer Metastatic or Locally Advanced

20 locations incl. Huntsville

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07080242·Phase 1·Recruiting

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Methadone Dose Monitoring With a Remote Medication Monitor

for Methadone Toxicity

1 location in Lemon Grove

Sponsor: Cari Health Inc.

Sex: All·Age: 18 - 70

Code: NCT06837571·Not Yet Recruiting

Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

for Fetal Alcohol Spectrum Disorders

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 8 - 12

Code: NCT06847165·Recruiting

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Ultrasound Stimulation for Patients in a Disorder of Consciousness

for Consciousness Disorders

4 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 79

Code: NCT06939348·Recruiting

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A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

for Metastatic Colorectal Cancer

Drug: Bevacizumab

13 locations incl. Duarte

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06820463·Phase 2·Recruiting

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A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

for Carcinoma, Non-Small-Cell Lung

Drug: Adagrasib

54 locations incl. Birmingham

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06875310·Phase 3·Recruiting

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Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for Severe Hypertriglyceridemia

Drug: Plozasiran

16 locations incl. Los Angeles

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06880770·Phase 3·Recruiting

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Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

for Metastatic Hepatocellular Carcinoma

9 locations incl. Los Angeles

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06915753·Phase 1·Recruiting

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Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia

for Pneumonia Childhood

4 locations incl. San Diego

Sponsor: Meyer Children's Hospital IRCCS

Sex: All·Age: 3 - 10

Code: NCT06921993·Recruiting

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Access Cannulation Trial II

for Dialysis

8 locations incl. Dothan

Sponsor: Voyager Biomedical

Sex: All·Age: 18+

Code: NCT05490225·Recruiting

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TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

for Mild Cognitive Impairment

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06548191·Phase 1·Recruiting

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MMA Embolization for Refractory Chronic Migraine

for Migraine Disorders

9 locations incl. Phoenix

Sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.

Sex: All·Age: 18 - 65

Code: NCT06735833·Recruiting

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A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

for Locally Advanced Breast Cancer

10 locations incl. Beverly Hills

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06827236·Phase 1, Phase 2·Recruiting

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SPL Insufficiency Syndrome (SPLIS)/NPHS14: a SPLIS Observational Study and Patient Registry (International)

for Sphingolipidoses

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04885179·Recruiting

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A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers

for Colorectal Carcinoma

2 locations incl. Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06568016·Recruiting

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Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

for Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06669949·Recruiting

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Study to Assess Safety, Efficacy, and Cellular Kinetics of YTB323 in Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

3 locations incl. Orange

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT06704269·Phase 1, Phase 2·Recruiting

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Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes

for Abortion

3 locations incl. San Diego

Sponsor: University of California, San Diego

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06820177·Phase 4·Recruiting

Apply to this trial