Age-dependent Effects of Smoked and Oral Delta-9-THC

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT05865470
Phase
PHASE1
Status
Recruiting
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Conditions

  • Abuse, Drug
  • Intoxication; Cannabinoids
  • Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Cannabis — DRUG
    smoked cannabis
  • Dronabinol — DRUG
    Oral delta-9-THC
  • Smoked Placebo — DRUG
    Placebo Cannabis
  • Oral Placebo — DRUG
    Oral Placebo

Study Details

This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.

Key Dates

Start date
Apr 30, 2025
Status verified
Jan 2026
Primary completion
Oct 15, 2028
Completion
Oct 15, 2029

Study Design

Enrollment
103 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: Placebo Comparator: Placebo
    Smoked Cannabis (0 mg THC) Oral placebo (0 mg THC)
  • Experimental: Experimental: Low strength cannabis
    Smoked Cannabis (10 mg THC) Oral placebo (0 mg THC)
  • Experimental: Experimental: Higher strength cannabis
    Smoked Cannabis (20 mg THC) Oral placebo (0 mg THC)
  • Experimental: Experimental: Low strength oral THC
    Smoked Cannabis (0 mg THC) Oral THC (10 mg THC)
  • Experimental: Experimental: Higher strength oral THC
    Smoked Cannabis (0 mg THC) Oral THC (20 mg THC)

Primary Outcome Measure

Subject-rated drug effects [ Time Frame: 6 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCLA Center for Cannabis and CannabinoidsLos AngelesCalifornia90095
Ziva D Cooper, PhD
[email protected]
(310) 794 -1497
Vince Acebo
[email protected]

Find similar trials in Los Angeles, CA

By research site
UCLA Center for Cannabis and Cannabinoids· Los Angeles, CA

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