Paid Clinical Trials in Boston, MA

As of June 2026, 3,013 paid clinical trials are recruiting in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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3,013 clinical trials

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Ph 2 Elacestrant in ER Positive Uterine Sarcomas

for Uterine Sarcoma

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT07467772·Phase 2·Recruiting

Apply to this trial

Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis

for Vascular Inflammation

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06691217·Phase 2·Recruiting

Apply to this trial

A Study of Orelabrutinib in Patients With Secondary Progressive Multiple Sclerosis

for Secondary Progressive Multiple Sclerosis

12 locations incl. Phoenix

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07299019·Phase 3·Recruiting

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Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)

for Von Hippel-Lindau Disease

3 locations incl. Boston

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07405164·Phase 3·Recruiting

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Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia

for Hypertension

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18 - 65

Code: NCT07238400·Phase 2·Recruiting

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Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

5 locations incl. Boston

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting

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A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1

for HIV

8 locations incl. Birmingham

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07390955·Phase 1·Recruiting

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Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter

for Joint Replacement Surgery

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages

Code: NCT07404982·Phase 2·Recruiting

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Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

for Tetrology of Fallot

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT07184476·Recruiting

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Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients

for Kidney Transplant Recipients

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 65+

Code: NCT06751992·Phase 4·Recruiting

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A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting

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Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

for HIV Infections

17 locations incl. Beverly Hills

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT07473778·Recruiting

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CAIX PET/CT for Residual or Recurrent Post-ablative ccRCC

for Clear Cell Renal Cell Carcinoma (ccRCC)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07077083·Phase 2·Not Yet Recruiting

The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

for Hemorrhagic Stroke

17 locations incl. Phoenix

Sponsor: phenox Inc.

Sex: All·Age: 18+

Code: NCT07143019·Recruiting

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A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

Apply to this trial

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

for Nicotine Dependence

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT07145866·Phase 4·Not Yet Recruiting

Assessing MB-Spirit for Psychological Well-being

for Stress

2 locations incl. Boston

Sponsor: Sara W Lazar

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT07325448·Recruiting

Apply to this trial

Stepped Care for Posttraumatic Stress Disorder Study

for Post Traumatic Stress Disorder

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06947538·Recruiting

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Yoga for Persistent Post-Surgical Pain (PPSP)

for Persistent Post-surgical Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06949007·Recruiting

Apply to this trial

Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

for Delirium

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 60+

Code: NCT07137949·Recruiting

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On-Trac: An Online Intervention for Cancer Survivors Managing Anxiety

for Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07305740·Recruiting

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Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

for Direct Care Workers

6 locations incl. San Diego

Sponsor: Rendever, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07430371·Recruiting

Apply to this trial

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

for Reproductive Disorder

1 location in Boston

Sponsor: Stephanie B. Seminara, MD

Sex: All·Age: 18 - 60

Code: NCT07224490·Phase 1·Recruiting

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BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

for Colorectal Cancer Prevention

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 80

Code: NCT07162337·Recruiting

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PDT For Induction Therapy For Head And Neck Cancer

for Squamous Cell Carcinoma

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT07214987·Phase 2·Not Yet Recruiting

Pre-NEOSHIFT-RCC: Neoadjuvant HIF-Inhibitor Immunotherapy in RCC

for Renal Cell Carcinoma

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT07397611·Phase 2·Recruiting

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A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Drug: FWY003

12 locations incl. Huntington Beach

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50+

Code: NCT07441642·Phase 2·Recruiting

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Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

for Pancreatic Cancer

Drug: daraxonrasib

5 locations incl. Baltimore

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07491445·Phase 3·Recruiting

Apply to this trial

A First-in-human Study of RLY-8161 in Advanced NRAS-Mutant Solid Tumors

for Advanced NRAS-Mutant Melanoma

6 locations incl. Los Angeles

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07584226·Phase 1·Recruiting

Apply to this trial

Ketamine add-on Therapy for Established Status Epilepticus Treatment Trial (KESETT)

for Status Epilepticus

52 locations incl. Tucson

Sponsor: University of Virginia

Sex: All·Age: 1+

Code: NCT06907173·Phase 3·Recruiting

Apply to this trial

Delivering tAN to Reduce HMB: The LUNA Study

for Heavy Menstrual Bleeding

1 location in Boston

Sponsor: Spark Biomedical, Inc.

Sex: Female·Age: 14 - 45

Code: NCT07326722·Recruiting

Apply to this trial

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

for Posttraumatic Stress Disorder

1 location in Boston

Sponsor: Boston University

Sex: Female·Age: 18+

Code: NCT07250061·Recruiting

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A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

for CRC (Colorectal Cancer)

Drug: Bevacizumab

80 locations incl. Chandler

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07284849·Phase 3·Recruiting

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

15 locations incl. Irvine

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting

Apply to this trial

Pilot Study of a Brain Health Program in Senior Centers

for Memory Loss (Excluding Dementia)

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50+

Code: NCT07424443·Recruiting

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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

4 locations incl. Glendale

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting

Apply to this trial

Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

for Primary Ovarian Insufficiency

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 30 - 40·Accepts healthy volunteers

Code: NCT06866119·Not Yet Recruiting

Finding Links Between Hot flASHes and CardioVascular Disease

for Menopause-related Hot Flashes

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 40 - 65

Code: NCT07077395·Phase 2·Recruiting

Apply to this trial

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease

for Parkinson's Disease

1 location in Boston

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07227896·Not Yet Recruiting

Resilient Families Feasibility Trial

for Parents

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07383948·Not Yet Recruiting