RecruitingPhase 2Drug trialEffects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal HematopoiesisThe primary goal of this clinical trial is to test the hypothesis that the drug canakinumab (anti-IL-1B monoclonal antibody) decreases vascular inflammation when used by people with a history of coronary artery disease, including those with and without clonal hematopoiesis driven by mutations in TET2.