Neurology Clinical Trials in Boston, MA

As of June 2026, 160 paid clinical trials are recruiting for Neurology in Boston, Massachusetts. Neurology trials investigate disease-modifying therapies for Alzheimer's, Parkinson's, multiple sclerosis, ALS, and stroke recovery alongside symptomatic treatments for epilepsy, migraine, and cognitive decline. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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160 clinical trials for Neurology

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A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)

for Multiple System Atrophy

Drug: Foralumab

1 location in Boston

Sponsor: Tiziana Life Sciences LTD

Sex: All·Age: 30 - 85

Code: NCT06868628·Phase 2·Recruiting

Apply to this trial

Assessment of Synaptic Density in MS

for Multiple Sclerosis

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT04634994·EARLY_Phase 1·Recruiting

Apply to this trial

Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2

for Intracerebral Hemorrhage

48 locations incl. Birmingham

Sponsor: Joseph Broderick, MD

Sex: All·Age: 18 - 80

Code: NCT07227246·Phase 3·Recruiting

Apply to this trial

Treating Insomnia in Mild Cognitive Impairment

for Mild Cognitive Impairment (MCI)

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 60+

Code: NCT06687161·Recruiting

Apply to this trial

Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons

for Parkinson Disease

1 location in Boston

Sponsor: Jeffrey S. Schweitzer, MD, PhD

Sex: All·Age: 45 - 80

Code: NCT06687837·Phase 1·Recruiting

Apply to this trial

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

for Multiple Sclerosis

8 locations incl. Boston

Sponsor: ModernaTX, Inc.

Sex: All·Age: 18 - 55

Code: NCT06735248·Phase 2·Recruiting

Apply to this trial

Vascular Mechanisms, Functional Outcomes, & Exercise Among Persons With Multiple Sclerosis With Hypertension

for Multiple Sclerosis

1 location in Boston

Sponsor: University of Massachusetts, Boston

Sex: All·Age: 18+

Code: NCT06554340·Recruiting

Apply to this trial

The DIAGNOSE CTE Research Project-II

for Chronic Traumatic Encephalopathy (CTE)

5 locations incl. Phoenix

Sponsor: Boston University

Sex: Male·Age: 50+·Accepts healthy volunteers

Code: NCT06860828·Enrolling By Invitation

TMS for Cognitive Decline in Aging and Preclinical AD

for Prodromal Alzheimer&#39

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40 - 99·Accepts healthy volunteers

Code: NCT06956300·Recruiting

Apply to this trial

Effectiveness of Cognitive Training in Older and Younger Adults

for Cognitive Change

3 locations incl. Riverside

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06375681·Recruiting

Apply to this trial

Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors

for Stroke

1 location in Boston

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 18 - 85

Code: NCT05626894·Phase 2·Recruiting

Apply to this trial

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

6 locations incl. Los Angeles

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting

Apply to this trial

EIM Via the Myolex mScan as an ALS Biomarker

for Amyotrophic Lateral Sclerosis

6 locations incl. Phoenix

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06491732·Recruiting

Apply to this trial

Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors

for Stroke

1 location in Boston

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 21 - 80

Code: NCT02896348·Recruiting

Apply to this trial

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

for Huntington Disease

5 locations incl. Boston

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 65

Code: NCT06826612·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

for Alzheimer Disease

40 locations incl. Phoenix

Sponsor: Lighthouse Pharmaceuticals, Inc.

Sex: All·Age: 55 - 80

Code: NCT06847321·Phase 2·Recruiting

Apply to this trial

A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: Remibrutinib

24 locations incl. Phoenix

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT06744920·Phase 3·Recruiting

Apply to this trial

StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

41 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting

Apply to this trial

Mindfulness for Cognition in Early-stage Alzheimer's Disease

for Mild Cognitive Impairment (MCI)

1 location in Boston

Sponsor: VA Boston Healthcare System

Sex: All·Age: 50 - 100·Accepts healthy volunteers

Code: NCT06792877·Recruiting

Apply to this trial

A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

for Parkinson Disease

45 locations incl. Sun City

Sponsor: Neuron23 Inc.

Sex: All·Age: 40 - 80

Code: NCT06680830·Phase 2·Recruiting

Apply to this trial

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

for Chronic Pain

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50+

Code: NCT06246929·Recruiting

Apply to this trial

RAPA-501 Therapy for ALS

for Amyotrophic Lateral Sclerosis

1 location in Boston

Sponsor: Rapa Therapeutics LLC

Sex: All·Age: 18+

Code: NCT04220190·Phase 2, Phase 3·Recruiting

Apply to this trial

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

for Stroke

7 locations incl. Chicago

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00682695·Recruiting

Apply to this trial

Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities

for Aging

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06989619·Recruiting

Apply to this trial

Deep Brain Stimulation (DBS) MatchMaker

for TOR1A

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06912841·Enrolling By Invitation

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

17 locations incl. San Francisco

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting

Apply to this trial

The CurePSP Genetics Program

for PSP

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT06647641·Recruiting

Apply to this trial

A Trial to Test if TEV-56286 is Effective for Treatment of Participants With Multiple System Atrophy

for Multiple System Atrophy

19 locations incl. La Jolla

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30 - 75

Code: NCT06568237·Phase 2·Recruiting

Apply to this trial

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

for Alzheimer Disease

Drug: KarXT

98 locations incl. Chandler

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT06585787·Phase 3·Recruiting

Apply to this trial

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

for Drug Resistant Epilepsy

3 locations incl. Palo Alto

Sponsor: NaviFUS Corporation

Sex: All·Age: 18+

Code: NCT06388707·Phase 1, Phase 2·Recruiting

Apply to this trial

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

for Migraine

Drug: Ubrogepant

103 locations incl. Birmingham

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06417775·Phase 3·Recruiting

Apply to this trial

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

for Huntington Disease

13 locations incl. Birmingham

Sponsor: Hoffmann-La Roche

Sex: All·Age: 25 - 60

Code: NCT06667414·Recruiting

Apply to this trial

Autologous iPSC-Derived Dopamine Neuron Transplantation for Parkinson's Disease

for Parkinson Disease

1 location in Boston

Sponsor: Penelope J. Hallett, Ph.D.

Sex: All·Age: 55 - 80

Code: NCT06422208·Phase 1·Enrolling By Invitation

Multi-Arm Multi-Stage Adaptive Platform Trial (APT) for the Acute Treatment of Traumatic Brain Injury

for Traumatic Brain Injury

18 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18 - 65

Code: NCT05826912·Phase 2·Enrolling By Invitation

A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG.

for Generalized Myasthenia Gravis

Drug: Iptacopan

21 locations incl. Scottsdale

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT06517758·Phase 3·Recruiting

Apply to this trial

A Multicenter Pediatric Deep Brain Stimulation Registry

for Dystonia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 18

Code: NCT06585618·Recruiting

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting

Apply to this trial

PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

31 locations incl. Birmingham

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting

Apply to this trial

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

87 locations incl. Birmingham

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting

Apply to this trial

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

for Brainstem Stroke

1 location in Boston

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT06511934·Recruiting

Apply to this trial

Conditions in Neurology (Boston, MA)

Stroke· 29 Alzheimer's disease· 22 Parkinson's disease· 22 Epilepsy· 17 Multiple sclerosis· 16 ALS (amyotrophic lateral sclerosis)· 15 Mild cognitive impairment (MCI)· 12 Dementia· 10 Cognitive impairment / decline· 9 Multiple system atrophy· 8 Movement disorders· 8 Myasthenia gravis· 7 Traumatic brain injury (TBI)· 5 Essential tremor· 4 Huntington disease· 3 Spinal cord injury· 3 Migraine· 2