Clinical Trials at University of Michigan

As of June 2026, 435 paid clinical trials are recruiting at University of Michigan, located at 1500 E MEDICAL CENTER DR, ANN ARBOR, MI 48109-5000, phone (734) 615-9888 in Ann Arbor, Michigan. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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435 clinical trials at University of Michigan

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Families in Balance: Enhancing Household Routines and Reducing Early Childhood Obesity Among Families With Low-income

for Health Behavior

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT06795490·Recruiting

Apply to this trial

A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

for Gastrointestinal Stromal Tumor (GIST)

32 locations incl. Birmingham

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06655246·Phase 1·Recruiting

Apply to this trial

Brief Pain Reprocessing Therapy in Veterans

for Chronic Lower Back Pain (CLBP)

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06771713·Recruiting

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NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients

for Sleep Apnea, Obstructive

2 locations incl. Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06677151·Recruiting

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A Study to Investigate the Efficacy and Safety of Sonrotoclax Plus Zanubrutinib Compared With Placebo Plus Zanubrutinib in Adults With Relapsed/Refractory Mantle Cell Lymphoma (CELESTIAL-RRMCL)

for Mantle Cell Lymphoma

Drug: Sonrotoclax

37 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06742996·Phase 3·Recruiting

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A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

for Gestational Hypertension

Drug: Dapagliflozin

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Female·Age: 18+

Code: NCT06785116·Phase 4·Recruiting

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EIM Via the Myolex mScan as an ALS Biomarker

for Amyotrophic Lateral Sclerosis

6 locations incl. Phoenix

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06491732·Recruiting

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Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0

for Acute Kidney Injury

50 locations incl. Birmingham

Sponsor: Indiana University

Sex: All·Age: 0 Minutes - 2 Weeks

Code: NCT06823115·Enrolling By Invitation

A Phase 1 Study of IM-1021 in Participants With Advanced Cancer

for Solid Malignancies

12 locations incl. Duarte

Sponsor: Immunome, Inc.

Sex: All·Age: 18+

Code: NCT06823167·Phase 1·Recruiting

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Multifocal HD-tDCS and Motor Function

for Healthy

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 65 - 85·Accepts healthy volunteers

Code: NCT06561165·Recruiting

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UBX-303061 in Subjects With Relapsed/Refractory B-Cell Malignancies

for Relapsed/Refractory B-cell Malignancies

3 locations incl. Ann Arbor

Sponsor: Ubix Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06590961·Phase 1·Recruiting

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Pro-2-Cool Pivotal Trial II

for Concussion, Mild

3 locations incl. Ann Arbor

Sponsor: TecTraum Inc.

Sex: All·Age: 13 - 21

Code: NCT06929923·Recruiting

Apply to this trial

Regenerative Peripheral Nerve Interface for Control of Lower Limb Prostheses

for Amputation

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 75

Code: NCT06275282·Recruiting

Apply to this trial

Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs

for Cardiac Failure

7 locations incl. Aurora

Sponsor: Inova Health Care Services

Sex: All·Age: Up to 18

Code: NCT06532890·Recruiting

Apply to this trial

A Study to Test Whether Spesolimab Helps People With a Skin Condition Called Pyoderma Gangrenosum

for Pyoderma Gangrenosum

19 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06624670·Phase 3·Recruiting

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BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

for AML, Adult Recurrent

6 locations incl. Duarte

Sponsor: BlueSphere Bio, Inc

Sex: All·Age: 18 - 70

Code: NCT06704152·Phase 1, Phase 2·Recruiting

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COMPASS: a Comprehensive Mobile Precision Approach for Scalable Solutions in Mental Health Treatment

for Mental Health

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06840457·Enrolling By Invitation

Promotion of Exercise Through Physical Therapy for Multiple Sclerosis: A Pilot Study

for Multiple Sclerosis

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06933160·Recruiting

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PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

for Depression

6 locations incl. Milford

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT06713616·Phase 3·Recruiting

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A Study to Evaluate Axatilimab and Corticosteroids as Initial Treatment for Chronic Graft-Versus-Host Disease

for Chronic Graft-versus-host-disease

33 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 12+

Code: NCT06585774·Phase 3·Recruiting

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SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma

for Melanoma, Cutaneous Malignant

40 locations incl. Phoenix

Sponsor: Immatics US, Inc.

Sex: All·Age: 18+

Code: NCT06743126·Phase 3·Recruiting

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Michigan Men's Diabetes Project III(MenDIII): Mind and Motion

for Diabetes Mellitus, Type 2

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Male·Age: 18+

Code: NCT06574035·Recruiting

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Optimizing Low Vision Rehabilitation in Emotionally Distressed Patients With Inherited Retinal Diseases

for Inherited Retinal Diseases

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT06651736·Recruiting

Apply to this trial

Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

for Surgery

4 locations incl. Los Angeles

Sponsor: University of Michigan

Sex: All·Age: 12 - 20

Code: NCT06671002·Phase 4·Recruiting

Apply to this trial

Adversity, Brain and Opioid Use Study

for Opioid Use Disorder

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06355778·Recruiting

Apply to this trial

Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4

for Anxiety

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 24

Code: NCT06563310·Recruiting

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Empower@Home: Community Implementation for Older Adults With Ambulatory Disabilities

for Depression

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT06721559·Recruiting

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Bioresorbable Airway Splint Pivotal Clinical Trial

for Tracheobronchomalacia

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 1 Week - 3

Code: NCT06406452·Recruiting

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The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life

for Systemic Sclerosis (SSc)

4 locations incl. New Orleans

Sponsor: Robyn T. Domsic, MD, MPH

Sex: All·Age: 18+

Code: NCT06675344·Recruiting

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Utility of Random Biopsies in Patients With Inflammatory Bowel Disease

for Inflammatory Bowel Diseases

20 locations incl. Birmingham

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06560021·Enrolling By Invitation

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

for Clinical Stage IA Cutaneous Melanoma AJCC v8

5 locations incl. Davis

Sponsor: OHSU Knight Cancer Institute

Sex: All·Age: 18+

Code: NCT06673095·Recruiting

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The JenaValve ALIGN-AR LVAD Registry

for Aortic Regurgitation

15 locations incl. Los Angeles

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: 18+

Code: NCT06594705·Recruiting

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BeCoMe-9: A Clinical Study of BE-101 for the Treatment of Adults With Moderately Severe or Severe Hemophilia B

for Hemophilia B

4 locations incl. Davis

Sponsor: Be Biopharma

Sex: Male·Age: 18+

Code: NCT06611436·Phase 1, Phase 2·Recruiting

Apply to this trial

Optimizing Care for Older Adults Through Thyroid Hormone Deprescribing

for Hypothyroidism

3 locations incl. San Francisco

Sponsor: University of Michigan

Sex: All·Age: 65+

Code: NCT06629272·Recruiting

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Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

6 locations incl. Los Angeles

Sponsor: Syntrix Biosystems, Inc.

Sex: Male·Age: 18+

Code: NCT06228053·Phase 2·Recruiting

Apply to this trial

Achieving Cardiovascular Health Equity in Community Mental Health: Optimizing Implementation Strategies

for Cardiovascular Risk Factors

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06674616·Enrolling By Invitation

MED-EL Remote Care Multi-Center Feasibility Study

for Hearing Loss, Sensorineural

3 locations incl. Iowa City

Sponsor: Med-El Corporation

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05973669·Enrolling By Invitation

Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis

for Knee Osteoarthritis

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT06580561·Recruiting

Apply to this trial

Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

for Glycogen Storage Disease Type Ia

9 locations incl. Orange

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 2+

Code: NCT06636383·Recruiting

Apply to this trial

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

for Nasopharyngeal Cancer Recurrent

12 locations incl. Little Rock

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 12+

Code: NCT06457503·Phase 4·Recruiting

Apply to this trial