Multifocal HD-tDCS and Motor Function

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT06561165
Status
Recruiting
Apply to this trial

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
65 Years - 85 Years
Healthy Volunteers
Accepted

Interventions

  • Standard HD-tDCS intervention — DEVICE
    Participants will have three sessions along with behavioral assessments.
  • Multifocal network targeted HD-tDCS intervention — DEVICE
    Participants will have three sessions along with behavioral assessments.
  • Functional Magnetic Resonance Imaging (fMRI) — DEVICE
    Participants will have an MRI before or after having HD-tDCS intervention.

Study Details

The purpose of this study is to understand how the brain controls movement and how Non-invasive Brain Stimulation (NIBS) with a technique called High-density transcranial direct current stimulation (HD-tDCS) can alter brain processes to improve behavior. Participants in this study will be randomized to either HD-tDCS with standard intervention or personalized dose-controlled multifocal network-targeted HD-tDCS. The hypothesis is that dexterous hand function will improve after a standard HD-tDCS dose and increase even more after personalized dose-controlled multifocal network-targeted HD-tDCS.

Key Dates

Start date
Feb 25, 2025
Status verified
Feb 2026
Primary completion
Jan 25, 2027
Completion
Jan 25, 2027

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: HD-tDCS with standard intervention
    Participants will have three daily sessions.
  • Experimental: Personalized dose-controlled multifocal network-targeted HD-tDCS.
    Participants will have three daily sessions.

Primary Outcome Measure

Percent change in precision force-tracking task [ Time Frame: Baseline and 24 hours after the third sessions are completed ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MichiganAnn ArborMichigan48109
Michael Vesia, PhD
[email protected]
734-764-5237
Michael Vesia, PhD (PRINCIPAL_INVESTIGATOR)

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University of Michigan· Ann Arbor, MI

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