Identification of Biomarkers for Stress Vulnerability and Resilience

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT05498207
Status
Recruiting
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Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 22 Years
Healthy Volunteers
Accepted

Interventions

  • Maya App — BEHAVIORAL
    Participants will utilize the Maya App for at least 20 minutes per day, 2 days per week, for 6 weeks. Additionally, participants will complete assessments at baseline, 3 months, 6 months, 9 months and 12 months (this includes specimen collections, interviews, and surveys). Participants will also be asked to wear a Fitbit for 12 months.

Study Details

The purpose of this research study is to understand the biological mechanisms of stress vulnerability (being susceptible to stress) and stress resilience (being able to recover readily from stress), obtain biomarkers (a biological indicator) for stress resilience and to devise strategies for prevention and treatment of stress-related disorders.

Key Dates

Start date
Aug 23, 2022
Status verified
Jun 2025
Primary completion
Oct 31, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
500 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • No Intervention: No Intervention
    Participants will complete assessments at baseline, 3 months, 6 months, 9 months and 12 months. (this includes specimen collections, interviews, and surveys). Participants will also be asked to wear a Fitbit for 12 months.
  • Experimental: Maya mobile app
    Maya mobile app- CBT based self-help app

Primary Outcome Measure

Change in anxiety symptoms based on the General Anxiety Disorder-7 Scale (GAD-7) between the intervention arm and the no intervention arm [ Time Frame: Baseline, up to 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MichiganAnn ArborMichigan48109
Virginia Weinberg
[email protected]
734-936-4820
Huda Akil, PhD (PRINCIPAL_INVESTIGATOR)
Juan Lopez, MD (SUB_INVESTIGATOR)
Cortney Turner, PhD (SUB_INVESTIGATOR)
Stanley Watson, MD, PhD (SUB_INVESTIGATOR)

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University of Michigan· Ann Arbor, MI

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