Trial results for a youth-led intervention aimed at improving blood pressure in adults with hypertension were posted on ClinicalTrials.gov on 2025-12-30, with 64 participants enrolled.
Background
Hypertension is a common chronic condition that requires ongoing management. Effective educational interventions are crucial for improving patient outcomes, especially when targeting specific populations and leveraging novel approaches. This study explored the potential of a youth-led education intervention designed as an electronic tool. The goal was for youth to learn about hypertension control and then teach adults, particularly those with uncontrolled hypertension (blood pressure ≥130/80 mm Hg), how to achieve better management.
Trial design
This completed study, designated as Phase NA, enrolled 64 participants. The trial focused on conditions including Hypertension, Adolescent Behavior, and Health Knowledge, Attitudes, Practice. The intervention involved developing and testing a youth-led hypertension education electronic tool designed to empower youth to learn about hypertension and then educate adults on achieving better control.
Key results
The trial reported several key measurements and analyses:
- School Cohort: Hypertension Knowledge (Youth and Adult):
- For Youth, mean scores were 17.5 (Standard Deviation 1.5) and 17.9 (Standard Deviation 2.7) out of 21 questions correct.
- For Adults, mean scores were 17.6 (Standard Deviation 1.7) and 17.8 (Standard Deviation 2.4) out of 21 questions correct.
- School Cohort: Youth Self-efficacy:
- Post-Intervention, mean scores for Youth were 8.2 (Standard Deviation 1.3), 8.9 (Standard Deviation 1.0), and 8.8 (Standard Deviation 1.6) on a scale.
- One-month Post-Intervention, mean scores for Youth were 8.7 (Standard Deviation 1.4), 9.0 (Standard Deviation 1.2), and 9.0 (Standard Deviation 1.3) on a scale.
- School Cohort: Adult Blood Pressure Self-care:
- Post-Intervention, the mean score for Adults was 4.9 (Standard Deviation 1.2) on a scale.
- One-month Post-Intervention, the mean score for Adults was 5.2 (Standard Deviation 0.9) on a scale.
Key analyses included Cohen's d effect sizes:
- Comparison of effect size: baseline to post-intervention (d1) was 1.337.
- Comparison of effect size: baseline to post-intervention (d2) was 1.337.
- Comparison of effect size: baseline to 1-month post-intervention (d1) was 1.3.
- Comparison of effect size: baseline to 1-month post-intervention (d2) was 1.159.
- Comparison of effect size: baseline to post-intervention (d1) was 1.065.
- Comparison of effect size: baseline to post-intervention (d2) was 1.084.
What this means
The posted results indicate that the youth-led hypertension education intervention was associated with improvements in hypertension knowledge for both youth and adults, increased youth self-efficacy, and enhanced adult blood pressure self-care. The reported Cohen's d effect sizes, ranging from 1.065 to 1.337, suggest a substantial positive impact of the intervention on these measured outcomes. These findings support the potential of youth-led educational models to improve health knowledge and self-management behaviors in the context of hypertension.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT05029687, titled "Youth-Led Intervention to Improve Blood Pressure", were posted on 2025-12-30 on clinicaltrials.gov.