Trial results for a study comparing two educational interventions for blood pressure medication adherence in hypertension were posted on ClinicalTrials.gov on 2026-02-24. The Habilidades Para Controlar la Presion (HCP) intervention group showed a mean objective medication adherence of 64.2%, while the Mi Propio Camino (MPC) group showed 54.9% among 511 enrolled participants.
Background
Hypertension, or high blood pressure, is a widespread chronic condition that requires consistent management, often involving daily medication. Poor adherence to prescribed blood pressure medications is a significant barrier to achieving blood pressure control, leading to increased risk of cardiovascular events and other complications. Educational interventions designed to improve medication adherence are critical for patients with uncontrolled hypertension, as they can empower individuals to better manage their condition and improve health outcomes.
Trial design
This completed study, designated as Phase NA, enrolled 511 participants with Hypertension and focused on Medication Adherence. The trial's purpose was to compare the effect of two educational interventions on adherence to blood pressure medications among adults with uncontrolled hypertension. The interventions studied were Mi Propio Camino (MPC; My Own Way) and Habilidades Para Controlar la Presion (HCP; Skills for Blood Pressure Control).
Key results
The trial reported several key measurements comparing the two educational interventions:
- Medication Adherence (Objective):
- For the Mi Propio Camino (MPC) group, the mean was 54.9 (Standard Deviation 38.7) percent days adherent.
- For the Habilidades Para Controlar la Presion (HCP) group, the mean was 64.2 (Standard Deviation 37.1) percent days adherent.
- Medication Adherence (Subjective):
- The Mi Propio Camino (MPC) group had a mean score of 5.4 (Standard Deviation 1.8) on a scale.
- The Habilidades Para Controlar la Presion (HCP) group had a mean score of 5.7 (Standard Deviation 1.6) on a scale.
- Number of Participants Who Were Nonadherent Due To Beliefs (Subjective):
- In the Mi Propio Camino (MPC) group, 62 participants were nonadherent due to beliefs.
- In the Habilidades Para Controlar la Presion (HCP) group, 71 participants were nonadherent due to beliefs.
- Medication-related Beliefs (Specific):
- The Mi Propio Camino (MPC) group showed a mean score of 3.3 (Standard Deviation 5.1) on a scale.
- The Habilidades Para Controlar la Presion (HCP) group showed a mean score of 3.5 (Standard Deviation 4.9) on a scale.
- Systolic Blood Pressure:
- The Mi Propio Camino (MPC) group had a mean of 137.2 (Standard Deviation 17.5) mmHg.
- The Habilidades Para Controlar la Presion (HCP) group had a mean of 136.2 (Standard Deviation 18.6) mmHg.
- Diastolic Blood Pressure:
- The Mi Propio Camino (MPC) group had a mean of 83.1 (Standard Deviation 10.9) mmHg.
- The Habilidades Para Controlar la Presion (HCP) group had a mean of 84.0 (Standard Deviation 12.3) mmHg.
What this means
The results indicate that the Habilidades Para Controlar la Presion (HCP) intervention was associated with a higher mean objective medication adherence compared to the Mi Propio Camino (MPC) intervention, with a difference of 9.3 percentage points in percent days adherent. While subjective adherence measures and blood pressure readings were similar between the two groups, the objective adherence data suggests that the HCP educational approach may be more effective in encouraging consistent medication taking among adults with uncontrolled hypertension. This highlights the potential for tailored educational strategies to improve real-world medication adherence, which is crucial for effective hypertension management.
Source
The information regarding these trial results was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study NCT04585594, titled "Mi Propio Camino Intervention RCT for Blood Pressure Medication Adherence", were posted on 2026-02-24 on clinicaltrials.gov.