Trial results for a virtual cardiometabolic health program for African immigrants, the Afro-DPP Program, were posted on ClinicalTrials.gov on 2026-04-22. The program showed mean reductions in systolic blood pressure of up to 11.4 mmHg over a 6-month period in participants with cardiometabolic risk factors including Type 2 Diabetes, PreDiabetes, and Hypertension.
Background
Cardiometabolic risk factors, including Type 2 Diabetes, PreDiabetes, Hypertension, and overweight/obesity, are significant public health concerns. Effective interventions are crucial for managing these conditions and improving health outcomes, particularly in specific populations that may face unique challenges in accessing care or adhering to traditional programs. Virtual health programs offer a potential avenue to deliver accessible and culturally relevant support.
Trial design
This completed pilot study, titled 'A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program,' enrolled a total of 60 participants. The study utilized a non-equivalent control group design to evaluate the effectiveness of the intervention. Participants had multiple cardiometabolic risk factors, including Diabetes Mellitus, Type 2 Diabetes, PreDiabetes, Hypertension, and High Blood Pressure. The intervention was a virtual cardiometabolic health program.
Key results
The study reported the following mean changes over a 6-month period:
- Change in Diastolic Blood Pressure (mm/Hg):
- Immediate Intervention group: 6.1 mmHg
- Delayed Intervention group: 10.3 mmHg
- Change in Systolic Blood Pressure (mm/Hg):
- First Intervention Group: 9.2 mmHg
- Delayed Intervention Group: 11.4 mmHg
- Change in Body Weight in Kilograms (kg):
- Immediate Intervention group: 4.9 kg
- Delayed Intervention group: 3.3 kg
- Change in Body Mass Index:
- First Intervention group: 1.1 Kg/m^2
- Delayed Intervention group: 0.3 Kg/m^2
What this means
The results suggest that a virtual cardiometabolic health program can lead to clinically meaningful reductions in key risk factors for Type 2 Diabetes and cardiovascular disease. Participants in the immediate intervention group experienced a mean reduction of 6.1 mmHg in diastolic blood pressure and 4.9 kg in body weight. The delayed intervention group showed even greater mean reductions in blood pressure, with 10.3 mmHg for diastolic and 11.4 mmHg for systolic blood pressure. These outcomes indicate the potential of such programs to improve cardiometabolic health in African immigrant communities, addressing hypertension and weight management.
Source
The information for this condition update was obtained from ClinicalTrials.gov, a public database of clinical studies. The results for the study 'A Virtual Cardiometabolic Health Program for African Immigrants: The Afro-DPP Program' were posted on 2026-04-22 on clinicaltrials.gov.
