Psychedelic Healing: Adjunct Therapy Harnessing Opened Malleability

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT07053917
Phase
PHASE1
Status
Recruiting
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Conditions

  • Chronic Stroke
  • Hemiparesis After Stroke
  • Hemiplegia Following Ischemic Stroke
  • Hemiplegia and Hemiparesis
  • Hemiplegia and/or Hemiparesis Following Stroke
  • Intracerebral Haemorrhage
  • Intracerebral Haemorrhage (ICH)
  • Intracerebral Hemorrhage Basal Ganglia
  • Ischemic Stroke
  • Ischemic Stroke and Hemorrhagic Stroke
  • Middle Cerebral Artery Stroke
  • Stroke

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Psilocybin (Usona Institute) — DRUG
    Participants will receive psilocybin to test its safety. Secondary outcomes will assess recovery from post-stroke deficits.

Study Details

The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.

Key Dates

Start date
Feb 9, 2026
Status verified
Feb 2026
Primary completion
Feb 28, 2027
Completion
Mar 31, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: 25 mg of psilocybin
    Participants will receive 25 mg of psilocybin
  • Experimental: 12.5 mg + 12.5 mg of psilocybin
    Participants will receive 12.5 mg of psilocybin followed by another 12.5 mg of psilocybin 2 hours after the first dose.

Primary Outcome Measure

Stability of systolic and diastolic blood pressure (mmHg) [ Time Frame: up to 24 hours post-psilocybin administration ]

Central Contacts

  • Steven R Zeiler, M.D., Ph.D.
    303-520-7404
    [email protected]
  • Victor C Urrutia, M.D.
    443-254-6435

Locations (1)

FacilityCityStateZIPSite coordinators
Johns HopkinsBaltimoreMaryland21287-

Find similar trials in Baltimore, MD

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
Johns Hopkins· Baltimore, MD

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