Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

Part of paid clinical trials in College Park, Maryland.

Sponsor
University of Maryland, College Park
Study ID
NCT06405594
Status
Recruiting
Apply to this trial

Conditions

  • Aphasia, Acquired
  • Healthy Aging
  • Stroke

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Language Condition — BEHAVIORAL
    The intervention involves asking participants to speak and understand words and sentences with different linguistic manipulations such as morphological, semantic, phonological priming, predictability of the subject and object nouns associated with verbs, naming of verbs and nouns, production of sentences with past, future or present tense. Accuracy, response times and brain activity are the outcome measures.

Study Details

The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this project lays the groundwork for development of new interventions, and aligns with NIDCD's priority areas 1 (understanding normal function), 2 (understanding diseases), and 3 (improving diagnosis, treatment, and prevention).

Key Dates

Start date
Aug 1, 2024
Status verified
Aug 2024
Primary completion
Jun 30, 2028
Completion
Jun 30, 2029

Study Design

Enrollment
350 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Language condition
    All participants will receive this arm. In this arm, the intervention involves asking participants to speak and understand words and sentences with different linguistic manipulations such as morphological, semantic, phonological priming, predictability of the subject and object nouns associated with verbs, naming of verbs and nouns, production of sentences with past, future or present tense. Accuracy, response times and brain activity are the outcome measures.

Primary Outcome Measure

Accuracy [ Time Frame: through the completion of the study, an average of 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MarylandCollege ParkMaryland20742
Yasmeen Faroqi-Shah, PhD
[email protected]
301-405-4229
Robert Slevc, PhD
[email protected]
(301) 405-5835

Find similar trials in College Park, MD

By condition
Stroke
By specialty
NeurologyBrain disorders
By research site
University of Maryland· College Park, MD

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