Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease

Part of paid clinical trials in Cleveland, Ohio.

Sponsor
VA Office of Research and Development
Study ID
NCT05400499
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

Inability to align and refocus the eyes on the objects at different depths, i.e., vergence impairment, frequently affects the quality of life in patients with Parkinson's disease. Our study aims to understand the location-specific effects of subthalamic region deep brain stimulation on vergence by integrating the patient-specific deep brain stimulation models and high-resolution eye-tracking measures. The knowledge gained will allow us to find the most beneficial stimulation location and parameters for improving binocular coordination and vergence while preserving the ability to treat motor symptoms in Parkinson's disease.

Key Dates

Start date
Oct 4, 2022
Status verified
Jan 2026
Primary completion
Jun 30, 2026
Completion
Jul 1, 2026

Study Design

Enrollment
40 participants (estimated)

Arms

  • Arm: Parkinson's disease with DBS
    This is the only group. The patients in this group will have bilateral subthalamic region deep brain stimulator. They will be recruited after they are therapeutically optimized on stimulation as well as medical therapy.

Primary Outcome Measure

Eye alignment [ Time Frame: once at the time of experiment, for 1 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Louis Stokes VA Medical Center, Cleveland, OHClevelandOhio44106-1702
Cheryl Dudek
[email protected]
216-679-3800
Aasef G Shaikh, MD PhD
[email protected]
(216) 791-3800
Aasef G. Shaikh, MD PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Cleveland, OH

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
Louis Stokes VA Medical Center, Cleveland, OH· Cleveland, OH

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