Fludarabine, Velcade and Rituximab for Relapsed or Refractory Follicular Non-Hodgkin Lymphoma

Part of paid clinical trials in Bloomington, Indiana.

Sponsor
Hoosier Cancer Research Network
Study ID
NCT01186458
Phase
PHASE2
Status
Terminated

Conditions

  • Lymphoma, Non-Hodgkin

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Fludarabine — DRUG
    Fludarabine 25 mg/m2 IV over 30 minutes on days 1, 2, 4. Cycle = 28 days; maximum of 6 cycles of therapy.
  • Velcade — DRUG
    Velcade (given after fludarabine)1.3 mg/m2 IV push over 3 to 5 seconds on days 1, 4, 8, 11. Cycle = 28 days; maximum of 6 cycles of therapy.
  • Rituximab — DRUG
    Rituximab given after Velcade) 375 mg/m2 IV piggyback on day 1. Cycle = 28 days; maximum of 6 cycles of therapy.

Study Details

The purpose of this study is to determine the effectiveness of fludarabine, Velcade, and rituximab treatment regimen in patients with relapsed or refractory follicular non-Hodgkin lymphoma.

Key Dates

Start date
Oct 31, 2010
Status verified
Aug 2016
Primary completion
Oct 31, 2013
Completion
Oct 31, 2013

Study Design

Enrollment
4 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Fludarabine, Velcade and Rituximab
    Fludarabine, Velcade and Rituximab

Primary Outcome Measure

Overall Response Rate [ Time Frame: 6 months ]

Locations (11)

FacilityCityStateZIPSite coordinators
Cancer Care Center of Southern IndianaBloomingtonIndiana47403-
Fort Wayne Oncology & Hematology, IncFort WayneIndiana46815-
Community Regional Cancer CenterIndianapolisIndiana46256-
Indiana University Melvin and Bren Simon Cancer CenterIndianapolisIndiana46202-
Arnett Cancer CareLafayetteIndiana47904-
Virtua Health Cancer ProgramMount HollyNew Jersey08060-
South Jersey Health CareVinelandNew Jersey08360-
University of Rochester Medical CenterRochesterNew York14642-
Case Comprehensive Cancer Center - University Hospitals Case Medical CenterClevelandOhio44106-
Seidman Cancer CenterClevelandOhio44106-
Reading Hospital Regional Cancer CenterWest ReadingPennsylvania19611-

Find similar trials in Bloomington, IN

By research site
Cancer Care Center of Southern Indiana· Bloomington, INFort Wayne Oncology & Hematology, Inc· Fort Wayne, INCommunity Regional Cancer Center· Indianapolis, INIndiana University Melvin and Bren Simon Cancer Center· Indianapolis, INArnett Cancer Care· Lafayette, INVirtua Health Cancer Program· Mount Holly, NJ

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