Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

Part of paid clinical trials in Scottsdale, Arizona.

Sponsor
Mayo Clinic
Study ID
NCT04996706
Status
Enrolling By Invitation

Conditions

  • Lymphoma, Non-Hodgkin

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this infrastructure protocol is to build and maintain a large and diverse observational cohort study to support broad and cutting-edge research focused on NHL prognosis and survivorship. The LEO cohort will promote identification of clinical (including co-morbid diseases), epidemiologic (including lifestyle and other exposures), host genetic, tumor, and treatment factors that impact multiple outcomes (including event-free, overall and lymphoma-specific survival; new onset comorbidities; and patient-reported outcomes). This resource also will allow examination of the interaction among these factors in order to better understand the clinical and molecular epidemiology of outcomes in NHL. Ultimately, this approach will drive discovery and validation of treatment endpoints, improve prognostication, and identify novel approaches to improve short and long-term outcomes for NHL patients.

Key Dates

Start date
Aug 16, 2021
Status verified
May 2026
Primary completion
Mar 31, 2031
Completion
Mar 31, 2031

Study Design

Enrollment
21,000 participants (estimated)

Primary Outcome Measure

Overall Survival (OS) [ Time Frame: Time Frame: Short (<5 years), medium (5-10 years), and long-term (>10 years) ]

Locations (12)

FacilityCityStateZIPSite coordinators
Mayo Clinic in ArizonaScottsdaleArizona85259-
Mayo Clinic in FloridaJacksonvilleFlorida32224-9980-
University of Miami: Sylvester Comprehensive Cancer CenterMiamiFlorida33136-
Emory St. Joseph's HospitalAtlantaGeorgia30342-
Emory University Hospital MidtownAtlantaGeorgia30308-
Winship Cancer Institute of Emory UniversityAtlantaGeorgia30322-
University of IowaIowa CityIowa52242-
Mayo ClinicRochesterMinnesota55902-
Washington University School of Medicine in St. LouisSt LouisMissouri63110-
Weill Cornell Medical CollegeNew YorkNew York10065-
University of Rochester Medical CenterRochesterNew York14642-
MD Anderson Cancer CenterHoustonTexas77030-

Find similar trials in Scottsdale, AZ

By research site
Mayo Clinic in Arizona· Scottsdale, AZMayo Clinic in Florida· Jacksonville, FLUniversity of Miami: Sylvester Comprehensive Cancer Center· Miami, FLEmory St. Joseph's Hospital· Atlanta, GAEmory University Hospital Midtown· Atlanta, GAWinship Cancer Institute of Emory University· Atlanta, GA

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