Paid Clinical Trials in Winston-Salem, NC

As of June 2026, 584 paid clinical trials are recruiting in Winston-Salem, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

Filter results

Filter results

State

City

Facility

Phase

Study type

Intervention

Recruitment status

Condition

Sex

Age

Healthy volunteers only

584 clinical trials

↓ Download CSV

BOOST: Blended Onsite and Offsite Structured Exercise Training and Coaching

for Heart Failure With Preserved Ejection Fraction

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 55+

Code: NCT07413198·Recruiting

Apply to this trial

Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias

for Myelofibrosis

Drug: Pacritinib

3 locations incl. Westwood

Sponsor: John Mascarenhas

Sex: All·Age: 18+

Code: NCT07447817·Phase 2·Not Yet Recruiting

Mode of Ventilation During Critical Illness at Multiple Centers

for Respiratory Failure

4 locations incl. Chicago

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07313956·Enrolling By Invitation

Evaluating the Efficacy of Platelet-rich Plasma Therapy in the Treatment of Androgenic Alopecia

for Androgenic Alopecia

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18+

Code: NCT03474718·EARLY_Phase 1·Not Yet Recruiting

System Interventions to Achieve Early and Equitable Transplants Study - Long-Term

for Chronic Kidney Diseases

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 75

Code: NCT07515794·Enrolling By Invitation

Telehealth and Remote Blood Pressure

for Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: 18 - 45

Code: NCT07356518·Recruiting

Apply to this trial

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

for Complex Regional Pain Syndrome Type I

12 locations incl. Phoenix

Sponsor: Ambros Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07210515·Phase 3·Recruiting

Apply to this trial

PROmega Pilot Study of Clinic-based DHA Blood Screening in Early Pregnancy

for Nutrient Deficiency

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: Female·Age: All ages

Code: NCT07271758·Enrolling By Invitation

Walk On! National Council on Aging Innovation Lab

for Falls Prevention

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07368907·Recruiting

Apply to this trial

Adapting and Implementing a Nurse Care Management Model to Care for Rural Patients With Chronic Pain

for Chronic Pain

1 location in Winston-Salem

Sponsor: University of Washington

Sex: All·Age: 18+

Code: NCT06407115·Enrolling By Invitation

Culturally Tailored Program for Food-Insecure Adults: SPICE-D

for Type 2 Diabetes Mellitus (T2D)

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07361341·Recruiting

Apply to this trial

A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

for Myelodysplastic Syndrome

18 locations incl. Orange

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07422480·Phase 3·Recruiting

Apply to this trial

A Mobile Patient Health Technology Intervention for Improving Lung Cancer Screening Rates in Eligible High Risk Patients

for Lung Cancer

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 50 - 77

Code: NCT07322367·Recruiting

Apply to this trial

Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway

for Cancer

2 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 65+

Code: NCT07175376·Recruiting

Apply to this trial

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

for Non-small Cell Lung Cancer (NSCLC)

Drug: Durvalumab

38 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361497·Phase 3·Recruiting

Apply to this trial

A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies

for Acute Myeloid Leukemia, in Relapse

3 locations incl. Charlotte

Sponsor: ARCE Therapeutics, Inc.

Sex: All·Age: All ages

Code: NCT06906380·Not Yet Recruiting

A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

40 locations incl. Daphne

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07361510·Phase 3·Recruiting

Apply to this trial

Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

for Sarcoma Metastatic

2 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07291297·Phase 2·Recruiting

Apply to this trial

Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter

for Intra-Abdominal Hypertension

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06876896·Recruiting

Apply to this trial

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

for Pulmonary Hypertension Associated With HFpEF

18 locations incl. Alexander City

Sponsor: Tenax Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07288398·Phase 3·Recruiting

Apply to this trial

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

Apply to this trial

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

for Corneal Edema

12 locations incl. Mesa

Sponsor: Aurion Biotech

Sex: All·Age: 18+

Code: NCT07368959·Phase 3·Recruiting

Apply to this trial

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

for Diabetic Macular Edema

Drug: Aflibercept

50 locations incl. Bakersfield

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07449936·Phase 3·Recruiting

Apply to this trial

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

for Menopausal Women

Drug: Daridorexant

5 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 40 - 62

Code: NCT07136415·Phase 4·Recruiting

Apply to this trial

Distance-Based Exercise to Preserve Function and Prevent Disability

for Hematopoietic and Lymphatic System Neoplasm

17 locations incl. Dublin

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07059884·Recruiting

Apply to this trial

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

for Smoking Behavior

2 locations incl. Charlotte

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07119489·Recruiting

Apply to this trial

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for Moderate to Severe Chronic Obstructive Pulmonary Disease

Drug: PF-07275315

30 locations incl. Dothan

Sponsor: Pfizer

Sex: All·Age: 35 - 80

Code: NCT07363694·Phase 2, Phase 3·Recruiting

Apply to this trial

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

16 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2·Recruiting

Apply to this trial

BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia

for Endotracheal Extubation

2 locations incl. Winston-Salem

Sponsor: Telethon Kids Institute

Sex: All·Age: 0 - 16

Code: NCT07204990·Recruiting

Apply to this trial

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

Apply to this trial

A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

11 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting

Apply to this trial

Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma Refractory

12 locations incl. San Francisco

Sponsor: CellCentric Ltd.

Sex: All·Age: 18+

Code: NCT07096778·Phase 2·Recruiting

Apply to this trial

Effects of Muscle Cooling on Motor Unit Firing of the Quadriceps

for Healthy

1 location in Winston-Salem

Sponsor: Wake Forest University

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT07381920·Recruiting

Apply to this trial

Vital Coach: A Study of Resiliency in Medical Students

for Burnout

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07342673·Recruiting

Apply to this trial

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

for Malignant Digestive System Neoplasm

58 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07215624·Recruiting

Apply to this trial

Horizon 360 Protocol for the Treatment of Paroxysmal Atrial Fibrillation With the Sphere-360™ Catheter and Affera™ Mapping and Ablation System (Horizon 360)

for Paroxysmal AF

15 locations incl. Jonesboro

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 80

Code: NCT07308847·Recruiting

Apply to this trial

Evaluation of Flexible Conductive Hearing Aids

for Conductive Hearing Loss

1 location in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 6 Months - 80·Accepts healthy volunteers

Code: NCT07222202·Recruiting

Apply to this trial

Understanding Needs of Older Patients Prior to Starting Cancer Treatment

for Hematopoietic and Lymphatic System Neoplasm

24 locations incl. Tuscaloosa

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225920·Enrolling By Invitation

Pyloric Sphincter Abnormalities in Patients With Gastroparesis Symptoms

for Gastroparesis

5 locations incl. Scottsdale

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT04661215·Recruiting

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic Acidosis

for CKD

19 locations incl. Chula Vista

Sponsor: Renibus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07355062·Phase 3·Recruiting

Apply to this trial