Paid Clinical Trials in Wilmington, NC

As of June 2026, 112 paid clinical trials are recruiting in Wilmington, North Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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112 clinical trials

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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

for Plaque Psoriasis

Drug: Deucravacitinib

122 locations incl. Birmingham

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 40+

Code: NCT07116967·Phase 3·Recruiting

Apply to this trial

Study to Evaluate the Efficacy and Safety of VQW-765 for the On-Demand Treatment of Social Anxiety Disorder

for Social Anxiety Disorder (SAD)

30 locations incl. Phoenix

Sponsor: Vanda Pharmaceuticals

Sex: All·Age: 18 - 65

Code: NCT07221578·Phase 3·Recruiting

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

652 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting

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Tenosynovial Giant Cell Tumor (TGCT) Real-World Participant Experience With Vimseltinib

for Tenosynovial Giant Cell Tumor

1 location in Wilmington

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT07075471·Recruiting

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OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

for Cardiovascular Disease

Drug: Olpasiran

204 locations incl. Alexander City

Sponsor: Amgen

Sex: All·Age: 50 - 105

Code: NCT07136012·Phase 3·Recruiting

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A Research Study to See How a Weekly Insulin, Insulin Icodec, Helps in Reducing the Blood Sugar Compared to Daily Insulin Glargine, Both in Combination With Insulin Aspart, in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

109 locations incl. Cullman

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07076199·Phase 3·Recruiting

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Real-World Efgartigimod Effectiveness in CIDP: A Prospective Study

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy

1 location in Wilmington

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07264426·Recruiting

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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

for Diabetes Mellitus, Type 2

Drug: Empagliflozin

216 locations incl. Anniston

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07064473·Phase 3·Recruiting

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Prospective Study to Assess a Diagnostic Aid for Cancer

for Cancer

39 locations incl. Coronado

Sponsor: Harbinger Health

Sex: All·Age: 45+

Code: NCT07046260·Recruiting

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Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users

for Systemic Lupus Erythematosus

1 location in Wilmington

Sponsor: AstraZeneca

Sex: Female·Age: All ages

Code: NCT06659029·Recruiting

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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

106 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting

Apply to this trial

RESTORE TRIAL: A Phase 2 Study Evaluating the Efficacy and Safety of Pemvidutide in the Treatment of Alcohol-Associated Liver Disease (ALD)

for Alcohol Liver Disease

Drug: Pemvidutide

42 locations incl. Peoria

Sponsor: Altimmune, Inc.

Sex: All·Age: 18 - 75

Code: NCT07009860·Phase 2·Recruiting

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

315 locations incl. Athens

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting

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A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

for Heart Failure

Drug: Empagliflozin

105 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06935370·Phase 3·Recruiting

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A Study of the Safety of Vonoprazan Exposure in Pregnant Women and Their Offspring

for Erosive Esophagitis

1 location in Wilmington

Sponsor: Phathom Pharmaceuticals, Inc.

Sex: Female·Age: 15 - 50

Code: NCT06660342·Recruiting

Apply to this trial

A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for Atopic Dermatitis

22 locations incl. Fountain Valley

Sponsor: Apogee Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07003425·Phase 2·Recruiting

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A Study to Train a Machine Learning Algorithm for an Evaluation of the Use of Biometric Data Captured at the Wrist for the Identification of Acute Opioid Use Events and the Quantification of Opioid Withdrawal in Opioid Dependent Individuals

for Treatment for Opioid Use Disorder

4 locations incl. Wilmington

Sponsor: OpiAID

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07405398·Recruiting

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IBD Pregnancy Registry

for Inflammatory Bowel Disease (IBD)

1 location in Wilmington

Sponsor: CorEvitas

Sex: Female·Age: 18 - 50

Code: NCT06910553·Recruiting

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Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis

for Severe Hypertriglyceridemia

Drug: Plozasiran

16 locations incl. Los Angeles

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06880770·Phase 3·Recruiting

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Designing Visual Tools to Enhance Cancer Surgeon Decision-making

for Prostate Cancer

2 locations incl. Chapel Hill

Sponsor: UNC Lineberger Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06965192·Recruiting

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Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

for Hypertriglyceridemia

Drug: Plozasiran

76 locations incl. Bakersfield

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06822790·Phase 3·Recruiting

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A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

for Ulcerative Colitis

100 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 80

Code: NCT06581328·Phase 4·Recruiting

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A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

for Chronic Obstructive Pulmonary Disease (COPD)

67 locations incl. Foley

Sponsor: AstraZeneca

Sex: All·Age: 40 - 80

Code: NCT06883305·Phase 3·Recruiting

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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

for Chronic Kidney Disease and Hypertension

Drug: Dapagliflozin

132 locations incl. Fairhope

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06742723·Phase 3·Recruiting

Apply to this trial

Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting

Apply to this trial

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

for CTCL/ Mycosis Fungoides

17 locations incl. Phoenix

Sponsor: Soligenix

Sex: All·Age: 18+

Code: NCT06470451·Phase 3·Recruiting

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Effectiveness and Safety of the RIGHTEST Continuous Glucose Monitoring System for Blood Glucose Management in Persons With Diabetes Mellitus

for Diabetes Mellitus

13 locations incl. Guntersville

Sponsor: Bionime Corporation

Sex: All·Age: 18+

Code: NCT04838392·Not Yet Recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

64 locations incl. Phoenix

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

29 locations incl. Birmingham

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting

Apply to this trial

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

for Melanoma

104 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06246916·Phase 3·Recruiting

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A Study to Evaluate Solrikitug in Participants With COPD (ZION)

for COPD

101 locations incl. Birmingham

Sponsor: Uniquity One (UNI)

Sex: All·Age: 40 - 75

Code: NCT06496620·Phase 2·Recruiting

Apply to this trial

Dose Optimization of Caffeine for HIE

for Hypoxic-Ischemic Encephalopathy

2 locations incl. Chapel Hill

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: Up to 24 Hours

Code: NCT06448780·Phase 1·Recruiting

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Continuation Protocol for Obstructive Sleep Apnea (OSA)

for OSA

93 locations incl. Birmingham

Sponsor: Apnimed

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06566820·Phase 3·Enrolling By Invitation

RSV Vaccine Pregnancy Registry

for Respiratory Syncytial Virus (RSV)

1 location in Wilmington

Sponsor: CorEvitas

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06521944·Recruiting

Apply to this trial

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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A Study Evaluating the Effect of BRIUMVI® (Ublituximab) on Pregnancy and Infant Outcomes in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

1 location in Wilmington

Sponsor: TG Therapeutics, Inc.

Sex: Female·Age: 15 - 50

Code: NCT06433765·Recruiting

Apply to this trial

Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

31 locations incl. Birmingham

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

134 locations incl. Birmingham

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting

Apply to this trial

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

for Heart Failure and Impaired Kidney Function

Drug: Dapagliflozin

166 locations incl. Alexander City

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06307652·Phase 3·Recruiting

Apply to this trial

Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

for Acne

79 locations incl. Scottsdale

Sponsor: Sanofi Pasteur, a Sanofi Company

Sex: All·Age: 18 - 45

Code: NCT06316297·Phase 1, Phase 2·Recruiting

Apply to this trial