A Study to Evaluate Solrikitug in Participants With COPD (ZION)

Part of paid clinical trials in Birmingham, Alabama.

Sponsor
Uniquity One (UNI)
Study ID
NCT06496620
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Biological: Solrikitug low dose — BIOLOGICAL
    Solrikitug subcutaneous injection
  • Biological: Solrikitug high dose — BIOLOGICAL
    Solrikitug subcutaneous injection
  • Placebo — OTHER
    Placebo subcutaneous injection

Study Details

A Randomized, Double-blind, Placebo-controlled, Multiple Dose-Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Participants with Chronic Obstructive Pulmonary Disease (COPD).

Key Dates

Start date
Aug 14, 2024
Status verified
Mar 2026
Primary completion
Jun 30, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
171 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Biological: Solrikitug High Dose
    Solrikitug
  • Other: Placebo
    Placebo
  • Experimental: Biological: Solrikitug Low Dose
    Solrikitug

Primary Outcome Measure

Change from baseline in blood eosinophil counts [ Time Frame: Through week 12 ]

Central Contacts

Locations (101)

FacilityCityStateZIPSite coordinators
University of Alabama at Birmingham HospitalBirminghamAlabama35294
Research Site 034
Syed Research ConsultantsSheffieldAlabama35660
Research Site 066
Phoenix Medical GroupPeoriaArizona85381
Research Site 099
Epic Medical Research-SurpriseSun CityArizona85351
Research Site 051
Alliance for Multispecialty ResearchTempeArizona85281
Research Site 033
Novak Clinical ResearchTucsonArizona85741
Research Site 095
Antelope Valley Clinical TrialsLancasterCalifornia93534
Research Site 031
Ark Clinical Research - BallingerLong BeachCalifornia90815
Research Site 107
Downtown LA Research Center, Inc.Los AngelesCalifornia90017
Research Site 032
Newport Native MD, Inc.Newport BeachCalifornia92663
Research Site 018
OM ResearchOxnardCalifornia93036
Research Site 041
Prospective Research Innovations, Inc.Rancho CucamongaCalifornia91730
Research Site 056
Velocity Clinical Research - DenverEnglewoodColorado80110
Research Site 020
Yale University School of MedicineNew HavenConnecticut06510-
Access Research InstituteBrooksvilleFlorida34613
Research Site 070
Clinical Research of West Florida - ClearwaterClearwaterFlorida33765
Research Site 002
Innovative Research of West Florida, Inc.ClearwaterFlorida33756
Research Site 049
JY Research InstituteCutler BayFlorida33189
Research Site 035
Hillcrest Medical Research, LLCDeLandFlorida32720
Research Site 077
North Florida Foundation for Research and EducationGainesvilleFlorida32608-
Direct Helper Research CenterHialeahFlorida33012
Research Site 064
Homestead Associates in Research Inc.HomesteadFlorida33033
Research Site 057
AppleMed Research Group, LLCMiamiFlorida33126
Research Site 111
Coral Research Clinic CorporationMiamiFlorida33186
Research Site 004
De La Cruz Research Center, LLCMiamiFlorida33184
Researcg Site 052
Reliant Medical Research LLCMiamiFlorida33165
Research Site 059
Valencia Medical & Research CenterMiamiFlorida33174
Research Site 098
Y&L Advanced Health Care, Inc.MiamiFlorida33144
Research Site 101
Pro-Care Research Center, Corp.Miami GardensFlorida33014
Research Site 038
San Marcus Research Clinic, Inc.Miami LakesFlorida33014
Research Site 055
Florida Institute for Clinical ResearchOrlandoFlorida32825
Research Site 013
Sarasota Clinical ResearchSarasotaFlorida34239
Research Site 007
TBC ResearchTamaracFlorida33321
Research Site 067
Clinical Research of West Florida - TampaTampaFlorida33606
Research Site 001
Appalachian Clinical Research, LLCAdairsvilleGeorgia30103
Research Site 108
Pulmonology, Sleep, Asthma, and Allergy Center - DublinDublinGeorgia31021-
CPCC - Research, LLCEast PointGeorgia30344
Research Site 110
Centricity ResearchRinconGeorgia31326
Research Site 003
Velocity Clinical Research - BoiseMeridianIdaho83642-
OSF HealthCare Saint Francis Medical CenterPeoriaIllinois61606
Research Site 079
Indiana Medical Research InstituteMerrillvilleIndiana46410-
The University of Kansas Medical CenterKansas CityKansas66160-
The Research Group of Lexington, LLCLexingtonKentucky40503-
Tandem Clinical ResearchMetairieLouisiana70006
Research Site 026
Care Access - ShreveportShreveportLouisiana71105
Research Site 097
Mayflower ClinicalSouth DartmouthMassachusetts02747
Research Site 017
Revival Research Institute, LLCDearbornMichigan48126
Research Site 114
Henry Ford Health SystemDetroitMichigan48207
Research Site 065
Pulmonary Research Institute of SE MichiganFarmington HillsMichigan48336
Research Site 037
Revive Research InstituteSouthfieldMichigan48075
Research Site 085
Midwest Chest ConsultantsSaint CharlesMissouri63301
Resarch Site 009
Montana Medical Research, Inc.MissoulaMontana59808
Research Site 062
Henderson TrialsHendersonNevada89052
Research Site 015
Rutgers, The State University of New JersyNew BrunswickNew Jersey08901
Research Site 105
Certified Research Associates Finger Lakes Medical Research, LLCCortlandNew York13045
Research Site 044
Corning Center for Clinical Research Smith Allergy & Asthma SpecialistsHorseheadsNew York14845
Research Site 043
Northwell HealthNew Hyde ParkNew York11042-
OnSite Clinical SolutionsCharlotteNorth Carolina28277
Research Site 050
Clinical Research of GastoniaGastoniaNorth Carolina28054
Research Site 005
Triad Clinical TrialsGreensboroNorth Carolina27410
Research Site 104
Peters Medical ResearchHigh PointNorth Carolina27260
Research Site 008
Advanced Respiratory and Sleep MedicineHuntersvilleNorth Carolina28078
Research Site 039
Accellacare WilmingtonWilmingtonNorth Carolina28401-
Southeastern Research CenterWinston-SalemNorth Carolina27103
Research Site 014
MetroHealth Medical CenterClevelandOhio44109-
Remington DavisColumbusOhio43215
Research Site 036
NexGen ResearchLimaOhio45801
Research Site 086
OK Clinical ResearchEdmondOklahoma73034
Research Site 115
Velocity Clinical Research - Grants PassGrants PassOregon97257-
Velocity Clinical Research - MedfordMedfordOregon97504
Research Site 011
Clinical Research Associates of Central PADuBoisPennsylvania15801
Research Site 083
Temple UniversityPhiladelphiaPennsylvania19140
Research Site 063
Allergy and Clinical Immunology AssociatesPittsburghPennsylvania15241
Research Site 053
University of Pittsburgh/UPMCPittsburghPennsylvania15213
Research Site 061
AnMed HealthAndersonSouth Carolina29621
Research Site 117
Velocity Clinical Research - AndersonAndersonSouth Carolina29621
Research Site 023
Medical University of South CarolinaCharlestonSouth Carolina29245
Research Site 069
Velocity Clinical Research - ColumbiaColumbiaSouth Carolina29204
Research Site 028
Velocity Clinical Research - GaffneyGaffneySouth Carolina29340
Research Site 030
Velocity Clinical Research - GreenvilleGreenvilleSouth Carolina29615-
Clinical Research of Rock HillRock HillSouth Carolina29732
Research Site 010
Velocity Clinical Research - SpartanburgSpartanburgSouth Carolina29303
Research Site 024
Velocity Clinical Research - UnionUnionSouth Carolina29379
Research Site 029
Pulmonary & Sleep SpecialistsDicksonTennessee37055-
Premier Research Center, LLCHendersonvilleTennessee37075
Research Site 040
New Phase Research & DevelopmentKnoxvilleTennessee37909
Research Site 048
TTS ResearchBoerneTexas78006
Research Site 016
Proactive RGVBrownsvilleTexas78520
Research Site 076
Ten20 Clinical Research, LLCCarrolltonTexas75010
Research Site 112
IntraCare Health CenterDallasTexas75254
Research Site 012
IntraCare ClinicalGreenvilleTexas75401
Research Site 089
Axsendo Clinical ResearchHoustonTexas77030-
Gulf Coast Clinical ResearchHoustonTexas77070
Research Site 025
R & H Clinical ResearchKatyTexas77494
Research Site 087
IntraCare Health CenterMcKinneyTexas75071
Research Site 012
SMS Clinical ResearchMesquiteTexas75149
Research Site 084
ADP Clinical ResearchSplendoraTexas77372
Research Site 109
Alpine Research Organization, Inc.LaytonUtah84041
Research Site 088
Velocity Clinical Research - HamptonHamptonVirginia23666
Research Site 019
Core ClinicalEverettWashington98201-
Confluence HealthWenatcheeWashington98801-

Find similar trials in Birmingham, AL

By condition
COPD
By specialty
PulmonologyLung disease
By research site
University of Alabama at Birmingham Hospital· Birmingham, ALSyed Research Consultants· Sheffield, ALPhoenix Medical Group· Peoria, AZEpic Medical Research-Surprise· Sun City, AZAlliance for Multispecialty Research· Tempe, AZNovak Clinical Research· Tucson, AZ

Related Studies