Clinical Trials at Children's National Hospital

As of June 2026, 80 paid clinical trials are recruiting at Children's National Hospital, located at Children's National Hospital, 111 Michigan Ave NW, Washington, DC 20010, phone (888) 884-2327 in Washington D.C., District of Columbia. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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80 clinical trials at Children's National Hospital

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Prospective Clinical Assessment Study in Children With Hypochondroplasia

for Hypochondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 30 Months - 16

Code: NCT06410976·Recruiting

Apply to this trial

Using Mobile Health (mHealth) to Improve STI Treatment Adherence Among Adolescents

for Sexually Transmitted Diseases

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 15 - 21

Code: NCT04372485·Recruiting

Apply to this trial

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

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Vosoritide for Short Stature in Turner Syndrome

for Turner Syndrome

Drug: Vosoritide

1 location in Washington D.C.

Sponsor: Roopa Kanakatti Shankar, MBBS, MS

Sex: Female·Age: 3 - 11

Code: NCT05849389·Phase 2·Recruiting

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Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

for Sickle Cell Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 2 - 25

Code: NCT06358638·Phase 2·Recruiting

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Navigating Pregnancy and Parenthood With Lyme Disease

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: Female·Age: 18+

Code: NCT06397794·Recruiting

Apply to this trial

Hydrogen's Feasibility and Safety as a Therapy in ECPR

for Cardiac Arrest

4 locations incl. Washington D.C.

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT05574296·Phase 1·Recruiting

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Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment

for Very Preterm Maturity of Infant

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: Up to 4 Weeks

Code: NCT06266455·Recruiting

Apply to this trial

Augmented Reality For MRI-Guided Interventions

for Infections

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 3 - 21·Accepts healthy volunteers

Code: NCT06224933·Recruiting

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Focused Ultrasound Pallidotomy for Dyskinetic Cerebral Palsy in Pediatric and Young Adult Subjects

for Cerebral Palsy, Dyskinetic

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 8 - 22

Code: NCT06036199·Recruiting

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Hospital to Home Study: Trial to Optimize Transitions and Address Disparities in Asthma Care

for Asthma

1 location in Washington D.C.

Sponsor: Kavita Parikh

Sex: All·Age: 4 - 12

Code: NCT05991115·Recruiting

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CHAMP App Cardiac Study and Repository

for Heart Defects, Congenital

9 locations incl. Washington D.C.

Sponsor: Lori Erickson

Sex: All·Age: Up to 18

Code: NCT06034392·Enrolling By Invitation

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

for Lyme Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 18+

Code: NCT06026969·Recruiting

Apply to this trial

Feasibility/Acceptability of Attentional-Control Training in Survivors

for Pediatric Cancer

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 8 - 16

Code: NCT05528939·Recruiting

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Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

for Refractory Ewing Sarcoma

Drug: Lurbinectedin

14 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 2 - 30

Code: NCT05734066·Phase 1, Phase 2·Recruiting

Apply to this trial

Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial

for Sexually Transmitted Diseases

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 15 - 21·Accepts healthy volunteers

Code: NCT04372875·Recruiting

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PAINED: Project Addressing INequities in the Emergency Department

for Pain

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 0+

Code: NCT05488080·Recruiting

Apply to this trial

International Rare Brain Tumor Registry

for Astroblastoma

6 locations incl. Los Angeles

Sponsor: Children's National Research Institute

Sex: All·Age: Up to 45

Code: NCT05697874·Recruiting

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Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease

for Sickle Cell Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 8 - 16

Code: NCT05099874·Recruiting

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Pediatric Dose Optimization for Seizures in Emergency Medical Services

for Seizures

20 locations incl. Tucson

Sponsor: Stanford University

Sex: All·Age: 6 Months - 13

Code: NCT05121324·Phase 3·Recruiting

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An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

for Hyperammonemia

5 locations incl. Washington D.C.

Sponsor: RECORDATI GROUP

Sex: All·Age: All ages

Code: NCT05040178·Recruiting

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Behavioral Intervention for Celiac Disease

for Celiac Disease

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 12 - 16

Code: NCT05204446·Enrolling By Invitation

Omalizumab Before Onset of Exacerbations

for Asthma in Children

Drug: Omalizumab

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 6 - 17

Code: NCT05332067·Phase 2·Recruiting

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Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts

for Viral Infection

3 locations incl. Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 3 Months - 80

Code: NCT04691622·Phase 1·Recruiting

Apply to this trial

Augmented Reality Ultrasound Guidance

for Paracentesis

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05964439·Recruiting

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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

for Respiratory Syncytial Virus Infections

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 3 Days - 2

Code: NCT05026749·Phase 3·Recruiting

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Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

for Medulloblastoma

8 locations incl. Los Angeles

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 39

Code: NCT05057702·Recruiting

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Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

for Solid Tumor

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 6 - 70

Code: NCT05238792·Phase 1·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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T Cell Therapy Opposing Novel COVID-19 Infection in Immunocompromised Patients

for SARS-CoV-2 Infection

2 locations incl. Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 2 - 80

Code: NCT05141058·Phase 1·Recruiting

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A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

11 locations incl. Washington D.C.

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting

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ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

for Diffuse Midline Glioma (DMG)

5 locations incl. San Francisco

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 2 - 21

Code: NCT04732065·Phase 1·Recruiting

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Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

for Langerhan's Cell Histiocytosis

12 locations incl. Phoenix

Sponsor: Carl Allen

Sex: All·Age: All ages

Code: NCT04079179·Phase 2·Recruiting

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Neurodevelopmental Outcomes in ZIKV-Exposed Children

for Zika Virus

1 location in Washington D.C.

Sponsor: Children's National Research Institute

Sex: All·Age: 3 - 7·Accepts healthy volunteers

Code: NCT04398901·Enrolling By Invitation

Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults

for Glioblastoma

14 locations incl. Birmingham

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 6 Months - 25

Code: NCT04323046·Phase 1·Recruiting

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Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study

for ADPKD

4 locations incl. Washington D.C.

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT04338048·Recruiting

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A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or Casimersen in Routine Clinical Practice

for Duchenne Muscular Dystrophy

20 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06606340·Enrolling By Invitation

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

for Pulmonary Invasive Fungal Infections

32 locations incl. Little Rock

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days - 21

Code: NCT03827694·Recruiting

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ARPKD Database Study

for Hepato/Renal Fibrocystic Disease

6 locations incl. Washington D.C.

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: Up to 18

Code: NCT01401998·Recruiting

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Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

for Charcot Marie Tooth Disease

18 locations incl. Los Angeles

Sponsor: Michael Shy

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01193075·Recruiting

Apply to this trial