International Rare Brain Tumor Registry

Conditions

• Astroblastoma
• BCOR ITD Sarcoma
• CNS Sarcoma
• Unclassified Tumor, Malignant

Eligibility Criteria

Sex

ALL

Age

N/A - 45 Years

Healthy Volunteers

Not accepted

Study Details

The objective of the International Rare Brain Tumor Registry (IRBTR) is to better understand rare brain tumors through the collection of biospecimens and matched clinical data of children, adolescents, and young adult patients diagnosed with rare brain tumors.

Key Dates

Start date

Jan 1, 2023

Status verified

Mar 2026

Primary completion

Dec 31, 2033

Completion

Dec 31, 2033

Study Design

Enrollment

5,800 participants (estimated)

Arms

• Arm: CNS Sarcoma
  Patients diagnosed with Central nervous system (CNS) sarcomas
• Arm: BCOR-altered
  Patients diagnosed with tumors characterized by alterations in the BCOR gene.
• Arm: Astroblastoma/MN-1- altered
  Patients diagnosed with Astroblastomas/MN-1 alterations
• Arm: Unclassifiable tumors
  Patients diagnosed with histologically ambiguous tumors or tumors that fail to classify with the current diagnostic methods.
• Arm: Other Rare Brain tumors
  Patients diagnosed with other rare brain tumors that do not meet the criteria for cohorts 1-4.

Primary Outcome Measure

Event-free Survival [ Time Frame: 10 years ]

Central Contacts

• Adriana Fonseca, MD
  202-476-8399
  [email protected]
• Hope Lovell
  202-476-3898
  [email protected]

Locations (6)

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