Paid Clinical Trials in Tennessee

Tennessee has 2,156 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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2,156 clinical trials

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A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) as First-line Maintenance Treatment of Cervical Cancer (MK-2870-036/TroFuse-036/GOG-3123/ENGOT-cx22)

for Cervical Cancer

16 locations incl. Miami Beach

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07216703·Phase 3·Recruiting

Apply to this trial

Digoxin Medulloblastoma Study

for Medulloblastoma

15 locations incl. Birmingham

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 12 Months - 30

Code: NCT06701812·Phase 2·Recruiting

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Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

for Head and Neck Cancer

2 locations incl. Philadelphia

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT06837480·Recruiting

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A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC)

for Renal Cell Carcinoma

Drug: BMS-986506

5 locations incl. Boston

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07195682·Phase 1·Recruiting

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Precision Brain Stimulation to Reduce Cannabis Craving in Schizophrenia

for Cannabis Use

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07196462·Recruiting

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Understanding Needs of Older Patients Prior to Starting Cancer Treatment

for Hematopoietic and Lymphatic System Neoplasm

24 locations incl. Tuscaloosa

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225920·Enrolling By Invitation

Non-inferiority Study of Frexalimab Subcutaneous Administration Compared to Intravenous Administration in Adult Participants With Multiple Sclerosis

for Multiple Sclerosis

Drug: Frexalimab

21 locations incl. Cullman

Sponsor: Sanofi

Sex: All·Age: 18 - 60

Code: NCT07325292·Phase 3·Recruiting

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Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for Fibromyalgia

16 locations incl. Little Rock

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07398417·Phase 3·Recruiting

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Delivering Patient-Facing Evidence-Based Guidelines Through mHealth to Adults With Sickle Cell Disease

for Sickle Cell Disease

4 locations incl. Chicago

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06919224·Recruiting

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A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

for Chronic Idiopathic Constipation (CIC)

Drug: Tenapanor

109 locations incl. Foley

Sponsor: Ardelyx

Sex: All·Age: 18 - 80

Code: NCT07382167·Phase 3·Recruiting

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

38 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting

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Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

for Obesity With Diabetes

34 locations incl. Cullman

Sponsor: Kailera

Sex: All·Age: 18+

Code: NCT07284901·Phase 3·Recruiting

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Carotid Implants for PreveNtion of STrokE ReCurrEnce From Large Vessel Occlusion in Atrial Fibrillation Patients Treated With Oral Anticoagulation

for Atrial Fibrillation

5 locations incl. Rockford

Sponsor: Javelin Medical

Sex: All·Age: 18+

Code: NCT05723926·Recruiting

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Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

for Diabetic Kidney Disease (DKD)

51 locations incl. Huntsville

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 80

Code: NCT07271186·Phase 2·Recruiting

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A Study of Buntanetap in Participants With PD

for Parkinson's Disease (PD)

27 locations incl. Birmingham

Sponsor: Annovis Bio Inc.

Sex: All·Age: 40 - 85

Code: NCT07284784·Phase 2, Phase 3·Recruiting

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DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

for Transthyretin Amyloidosis With Cardiomyopathy

4 locations incl. Naples

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07358078·Recruiting

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A Study to Assess A Change in Disease Activity and Adverse Events of Intravenous Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Adult Participants With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant

for Multiple Myeloma

Drug: Daratumumab

17 locations incl. Scottsdale

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07095452·Phase 2, Phase 3·Recruiting

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A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

8 locations incl. Duarte

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting

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A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

for Overweight

34 locations incl. Escondido

Sponsor: Novo Nordisk A/S

Sex: All·Age: 8 - 18

Code: NCT07253285·Phase 3·Recruiting

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Nordic Spirit Pouch Nicotine Pharmacokinetics Abuse Liability

for Smoking Behaviors

2 locations incl. Knoxville

Sponsor: JT International SA

Sex: All·Age: 22 - 65·Accepts healthy volunteers

Code: NCT07476144·Phase 1·Recruiting

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Lead Evaluation for Defibrillation and Reliability Post Approval Study

for Tachyarrhythmia

46 locations incl. Birmingham

Sponsor: Medtronic

Sex: All·Age: All ages

Code: NCT07005232·Enrolling By Invitation

The ArtixASCEND Study

for Acute Lower Limb Arterial Occlusion

14 locations incl. New Haven

Sponsor: Inari Medical

Sex: All·Age: 18+

Code: NCT07135895·Recruiting

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Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

for Advanced Non-Small Cell Lung Cancer

Drug: PF-08634404

184 locations incl. Bullhead City

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222566·Phase 3·Recruiting

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Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies

for Lymphoma Diffuse Large B-cell

5 locations incl. Chicago

Sponsor: AvenCell Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07284433·Phase 1, Phase 2·Recruiting

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Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1

for HIV-1

11 locations incl. Los Angeles

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: Up to 72 Hours·Accepts healthy volunteers

Code: NCT06517693·Phase 1·Recruiting

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A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

for Major Depressive Disorder

32 locations incl. Phoenix

Sponsor: Syndeio Biosciences, Inc

Sex: All·Age: 18 - 64

Code: NCT07115329·Phase 2·Recruiting

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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Drug: Navlimetostat

42 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07063745·Phase 2, Phase 3·Recruiting

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Vanderbilt Integrated Community TMS for Opioid Recovery

for Opiod Use Disorder

2 locations incl. Brentwood

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18 - 65

Code: NCT07457489·Recruiting

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A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

for Untreated, Unresectable, or Metastatic Colorectal Cancer

Drug: Bevacizumab

49 locations incl. Tucson

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07221357·Phase 2, Phase 3·Recruiting

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Hyperangulated Versus Standard Geometry Laryngoscope Blade Trial

for Acute Respiratory Failure

16 locations incl. Los Angeles

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07223762·Enrolling By Invitation

A Study of a Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

for Advanced Solid Tumor, Adult

6 locations incl. Grand Rapids

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07361562·Phase 1·Recruiting

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Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

for Advanced HR+/HER2- Breast Cancer

Drug: GVV858

1 location in Nashville

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07288359·Phase 1, Phase 2·Recruiting

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Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH

for MASH - Metabolic Dysfunction-Associated Steatohepatitis

16 locations incl. La Jolla

Sponsor: Madrigal Pharmaceuticals, Inc.

Sex: All·Age: 18 - 75

Code: NCT07335601·Phase 2·Recruiting

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A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

for Degenerative Disc Disease

14 locations incl. Birmingham

Sponsor: DiscGenics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07254806·Phase 3·Recruiting

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A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

for Breast Neoplasms

117 locations incl. Anchorage

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07174336·Phase 3·Recruiting

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Phase 2A/B Efficacy and Safety of Dabogratinib in Participants With Low Grade Upper Tract Urothelial Carcinoma

for Low Grade Upper Tract Urothelial Carcinoma

7 locations incl. Lisle

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT07265947·Phase 2·Recruiting

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A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

for Prostatic Neoplasms, Castration-Resistant

Drug: Pasritamig

49 locations incl. Chandler

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07225946·Phase 3·Recruiting

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ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

for AChR-Ab Seropositive Generalized Myasthenia Gravis

Drug: Empasiprubart IV

8 locations incl. Carlsbad

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07284420·Phase 2·Recruiting

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

17 locations incl. Little Rock

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting

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ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

for Myasthenia Gravis

9 locations incl. Carlsbad

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT07294170·Recruiting

Apply to this trial