Paid Clinical Trials in Tennessee

Tennessee has 2,155 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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2,157 clinical trials

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A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

for Advanced Cancer

15 locations incl. Los Angeles

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05557045·Phase 1·Recruiting

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Response to Influenza Vaccination in Pediatric Oncology Patients

for Hematologic Malignancy

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 18

Code: NCT05384288·Recruiting

Apply to this trial

A Study of AND019 in Women With ER Positive HER2 Negative Advanced or Metastatic Breast Cancer

for Advanced or Metastatic Breast Cancer

1 location in Nashville

Sponsor: Kind Pharmaceuticals LLC

Sex: Female·Age: 18+

Code: NCT05187832·Phase 1·Recruiting

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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

for Ulcerative Colitis

22 locations incl. Irvine

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT05230173·Recruiting

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Met Non Small Cell Cancer Registry (MOMENT)

for Cancer

3 locations incl. Fort Lauderdale

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: All ages

Code: NCT05376891·Recruiting

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The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

for Knowledge, Attitudes, Practice

1 location in Memphis

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT05454618·Recruiting

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Returning to Everyday Tasks Utilizing Rehabilitation Networks-III (RETURN-III)

for Cognitive Rehabilitation

2 locations incl. Nashville

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04353804·Recruiting

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Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

for Barrett Esophagus

14 locations incl. Gilbert

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05530343·Recruiting

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting

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Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults

for Dehydration

1 location in Memphis

Sponsor: Liquid I.V.

Sex: All·Age: 18 - 35·Accepts healthy volunteers

Code: NCT05428228·Recruiting

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A Study of EP0031 in Patients With Advanced RET-altered Malignancies

for Advanced Solid Tumor

Drug: EP0031

18 locations incl. Los Angeles

Sponsor: Ellipses Pharma

Sex: All·Age: 18+

Code: NCT05443126·Phase 1, Phase 2·Recruiting

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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

22 locations incl. Birmingham

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting

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Post-Market Study to Assess iTind Safety in Comparison to UroLift

for Benign Prostatic Hyperplasia (BPH)

15 locations incl. Phoenix

Sponsor: Olympus Corporation of the Americas

Sex: Male·Age: 50+

Code: NCT04757116·Recruiting

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

36 locations incl. Huntsville

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting

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A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

for Non-muscle-invasive Bladder Cancer

11 locations incl. Little Rock

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT05483868·Phase 1·Recruiting

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A Clinical Study to Assess the Efficacy and Safety of Alpha DaRT224 for the Treatment of Patients With Recurrent Cutaneous Squamous Cell Carcinoma

for Recurrent Squamous Cell Carcinoma

25 locations incl. Gilbert

Sponsor: Alpha Tau Medical LTD.

Sex: All·Age: 18+

Code: NCT05323253·Recruiting

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A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

for Relapsed or Refractory Multiple Myeloma

Drug: Mezigdomide

56 locations incl. Los Alamitos

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT05519085·Phase 3·Recruiting

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Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

for Prostate Cancer

32 locations incl. Birmingham

Sponsor: Janux Therapeutics

Sex: Male·Age: 18 - 100

Code: NCT05519449·Phase 1·Recruiting

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A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

for Subacute Cutaneous Lupus Erythematosus

61 locations incl. Anniston

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT05531565·Phase 2, Phase 3·Recruiting

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

42 locations incl. Phoenix

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting

Apply to this trial

You and Me Healthy

for COVID-19

3 locations incl. Merced

Sponsor: Duke University

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT05589376·Enrolling By Invitation

Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung Disease

for Idiopathic Pulmonary Fibrosis

86 locations incl. Birmingham

Sponsor: United Therapeutics

Sex: All·Age: 40+

Code: NCT04905693·Phase 3·Enrolling By Invitation

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

for Hypereosinophilic Syndrome

Drug: Depemokimab

11 locations incl. San Diego

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT05334368·Phase 3·Recruiting

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Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

for Endometrial Cancer

18 locations incl. Los Angeles

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT05489211·Phase 2·Recruiting

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TVMR With the INNOVALVE System Trial - Early Feasibility Study

for Mitral Valve Regurgitation (Degenerative or Functional)

20 locations incl. Los Angeles

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04919980·Recruiting

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Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

16 locations incl. Los Angeles

Sponsor: ModernaTX, Inc.

Sex: All·Age: 12+

Code: NCT05533697·Phase 1, Phase 2·Recruiting

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Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for Platinum-resistant Ovarian Cancer

Drug: Bevacizumab

31 locations incl. Mobile

Sponsor: Genelux Corporation

Sex: Female·Age: 18+

Code: NCT05281471·Phase 3·Recruiting

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Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

for Breast Neoplasms

11 locations incl. Fullerton

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05386108·Phase 1, Phase 2·Recruiting

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Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

for Metastatic Breast Cancer

Drug: Palazestrant

14 locations incl. Gilbert

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05508906·Phase 1·Recruiting

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Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC.

for Small Cell Lung Cancer

11 locations incl. Encinitas

Sponsor: Chipscreen Biosciences, Ltd.

Sex: All·Age: 18+

Code: NCT05271292·Phase 1, Phase 2·Recruiting

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Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for HR+/HER2-negative Breast Cancer

10 locations incl. Loma Linda

Sponsor: SynDevRx, Inc.

Sex: All·Age: 18+

Code: NCT05455619·Phase 1, Phase 2·Recruiting

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Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

for HER2-Positive Solid Tumor

2 locations incl. Boston

Sponsor: Yuhan Corporation

Sex: All·Age: 18+

Code: NCT05523947·Phase 1, Phase 2·Recruiting

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A Prospective Sub-Study of the Global Hypophosphatasia Registry

for Hypophosphatasia

12 locations incl. Hartford

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: All ages

Code: NCT05234567·Recruiting

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A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

58 locations incl. Homewood

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05511363·Phase 3·Recruiting

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

746 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting

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Study of the CycloPen Micro-Interventional System and Long-Term Clinical Outcomes

for Open Angle Glaucoma

15 locations incl. Newport Beach

Sponsor: Iantrek, Inc.

Sex: All·Age: 21+

Code: NCT05506423·Enrolling By Invitation

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

Drug: Mavacamten

62 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting

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A Study of XMT-1660 in Participants With Solid Tumors

for Triple Negative Breast Cancer

26 locations incl. Phoenix

Sponsor: Mersana Therapeutics

Sex: All·Age: 18+

Code: NCT05377996·Phase 1·Recruiting

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A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

for Lymphoma, Non-Hodgkin

14 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05421663·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of LT3001 Drug Product in Subjects AIS Undergoing EVT

for Acute Ischemic Stroke

1 location in Chattanooga

Sponsor: Lumosa Therapeutics Co., Ltd.

Sex: All·Age: 18 - 90

Code: NCT05198323·Phase 2·Recruiting

Apply to this trial