Paid Clinical Trials in Tennessee

Tennessee has 2,155 paid clinical trials enrolling now across cities including Nashville, Memphis and Knoxville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Tennessee include Vanderbilt University Medical Center and St. Jude Children's Research Hospital, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 15, 2026.

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2,155 clinical trials

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HPC Offered for PRESERVE Expansion

for Bone Marrow Transplant (BMT)

4 locations incl. Birmingham

Sponsor: Ossium Health, Inc.

Sex: All·Age: 12 - 80

Code: NCT07145411·Recruiting

Apply to this trial

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

101 locations incl. Phoenix

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting

Apply to this trial

Inpatient Monitoring of Unfractionated Heparin

for Blood Clot

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06329921·Enrolling By Invitation

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

for Stage II Nasopharyngeal Carcinoma AJCC v8

Drug: Nivolumab

76 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT06064097·Phase 2·Recruiting

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ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

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Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

for Generalized Myasthenia Gravis

21 locations incl. Phoenix

Sponsor: Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06463587·Phase 3·Recruiting

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Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

for Transthyretin Amyloidosis

30 locations incl. La Jolla

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06465810·Recruiting

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A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

for Head and Neck Squamous Cell Carcinoma

Drug: Petosemtamab

61 locations incl. Mobile

Sponsor: Merus B.V.

Sex: All·Age: 18+

Code: NCT06496178·Phase 3·Recruiting

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

371 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06203600·Phase 2, Phase 3·Recruiting

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Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)

for Triple-Negative Breast Cancer

88 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06393374·Phase 3·Recruiting

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Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas

for Empyema, Pleural

5 locations incl. Sterling Heights

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT06427538·Recruiting

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The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

for Peripheral Arterial Disease

20 locations incl. Scottsdale

Sponsor: Avantec Vascular

Sex: All·Age: 18+

Code: NCT06321575·Recruiting

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A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

for Leukemia

13 locations incl. Duarte

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06501196·Phase 1·Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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Study of SGR-3515 In Participants With Advanced Solid Tumors.

for Advanced Solid Tumor

13 locations incl. New Haven

Sponsor: Schrödinger, Inc.

Sex: All·Age: 18+

Code: NCT06463340·Phase 1·Recruiting

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Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

for Large B-cell Lymphoma

60 locations incl. Gilbert

Sponsor: Allogene Therapeutics

Sex: All·Age: 18+

Code: NCT06500273·Phase 2·Recruiting

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A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

for Sickle Cell Disease

16 locations incl. Oakland

Sponsor: Editas Medicine, Inc.

Sex: All·Age: 12 - 50

Code: NCT06363760·Enrolling By Invitation

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

for Heart Failure

Drug: Empagliflozin

95 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06424288·Phase 3·Recruiting

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Tissue Growth Characterization for Cochlear Implant Users

for Cochlear Implant

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT04320251·Enrolling By Invitation

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

for Biliary Tract Cancer

6 locations incl. Denver

Sponsor: ModeX Therapeutics, An OPKO Health Company

Sex: All·Age: 18+

Code: NCT06239194·Phase 1, Phase 2·Recruiting

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GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab

for Type 1 Diabetes

1 location in Nashville

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 12 - 50

Code: NCT06338553·EARLY_Phase 1·Recruiting

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A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

for Parkinson Disease

27 locations incl. Irvine

Sponsor: AskBio Inc

Sex: All·Age: 45 - 75

Code: NCT06285643·Phase 2·Recruiting

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Pain With Differing Insufflation Pressures During Laparoscopic Hysterectomy

for Post Operative Pain

1 location in Memphis

Sponsor: University of Tennessee

Sex: Female·Age: 18 - 80·Accepts healthy volunteers

Code: NCT06508814·Recruiting

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

53 locations incl. Anchorage

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

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Study of NXC-201 CAR-T in Patients With Light Chain (AL) Amyloidosis

for Light Chain (AL) Amyloidosis

18 locations incl. Berkeley

Sponsor: Nexcella Inc.

Sex: All·Age: 18 - 120

Code: NCT06097832·Phase 1, Phase 2·Recruiting

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IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301)

for Advanced Melanoma

Drug: Nivolumab

37 locations incl. Tucson

Sponsor: Immunocore Ltd

Sex: All·Age: 18+

Code: NCT06112314·Phase 3·Recruiting

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Prospective Clinical Assessment Study in Children With Hypochondroplasia

for Hypochondroplasia

8 locations incl. Oakland

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 30 Months - 16

Code: NCT06410976·Recruiting

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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for Crohn's Disease

Drug: Tulisokibart

87 locations incl. Dothan

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16 - 80

Code: NCT06430801·Phase 3·Recruiting

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Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

for Metastatic Breast Cancer

29 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06324357·Phase 1, Phase 2·Recruiting

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Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

58 locations incl. Birmingham

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting

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A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor, Adult

10 locations incl. Denver

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06507306·Phase 1·Recruiting

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Does Starting Feeds on the First Day of Life Help Premature Infants Reach Full Volume Feeds Sooner?

for Extra Uterine Growth Restriction

1 location in Memphis

Sponsor: University of Tennessee

Sex: All·Age: 1 Minute - 6 Hours

Code: NCT06731439·Recruiting

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Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease

for Sickle Cell Disease (SCD)

31 locations incl. Birmingham

Sponsor: University of Rochester

Sex: All·Age: 3 - 20

Code: NCT06941389·Recruiting

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Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors

for Digestive System Neuroendocrine Tumor G1

1 location in Nashville

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT06016855·Phase 4·Recruiting

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Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

for Anatomic Stage I Breast Cancer

5 locations incl. Atlanta

Sponsor: Vanderbilt-Ingram Cancer Center

Sex: All·Age: 18+

Code: NCT05919108·Phase 2·Recruiting

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A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

135 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting

Apply to this trial

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

for Colorectal Cancer

32 locations incl. Chandler

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06445062·Phase 1, Phase 2·Recruiting

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Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

for Non-small Cell Lung Cancer

22 locations incl. Birmingham

Sponsor: TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

Sex: All·Age: 18+

Code: NCT06343402·Phase 1·Recruiting

Apply to this trial