Clinical Trials at Moffitt Cancer Center

As of June 2026, 301 paid clinical trials are recruiting at Moffitt Cancer Center, located at 12902 USF MAGNOLIA DR, TAMPA, FL 33612-9416, phone (813) 745-3862 in Tampa, Florida. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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301 clinical trials at Moffitt Cancer Center

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Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

for Oropharyngeal Cancer

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06305676·Recruiting

Apply to this trial

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

for GastroEsophageal Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06109467·Phase 2·Recruiting

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A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for Metastatic Head-and-neck Squamous-cell Carcinoma

28 locations incl. Gilbert

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06064877·Phase 3·Recruiting

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A Global Study of the PETAL Consortium

for T-Cell and NK-Cell Neoplasm

10 locations incl. Duarte

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06067347·Recruiting

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A Study to Assess BMS-986458 Alone and in Combination With Anti-lymphoma Agents in Relapsed/Refractory Non-Hodgkin Lymphomas

for Relapsed/Refractory Non-Hodgkin Lymphoma

14 locations incl. Phoenix

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06090539·Phase 1, Phase 2·Recruiting

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Dose Escalation and Expansion Study of BH3120 Alone or With Pembrolizuamb in Advanced or Metastatic Solid Tumors

for Advanced or Metastatic Solid Tumors

5 locations incl. Tampa

Sponsor: Hanmi Pharmaceutical Company Limited

Sex: All·Age: 18+

Code: NCT06234397·Phase 1·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sutetinib Maleate Capsule in Locally Advanced or Metastatic NSCLC

for Non-small Cell Lung Cancer

9 locations incl. Glendale

Sponsor: Teligene US

Sex: All·Age: 18+

Code: NCT06010329·Phase 2·Recruiting

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Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for B-Cell Lymphoblastic Leukemia

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06144606·Phase 2·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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Phase 2 Trial of Adaptive Radiotherapy Boost for HNSCC

for Squamous Cell Carcinoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06137274·Phase 2·Recruiting

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Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

for Chronic Graft Versus Host Disease

5 locations incl. Duarte

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05996627·Phase 2·Recruiting

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A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

for Non-small Cell Lung Cancer

Drug: Intismeran autogene

68 locations incl. Anchorage

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06077760·Phase 3·Recruiting

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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

16 locations incl. Davis

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting

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Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

for Soft Tissue Sarcoma

26 locations incl. Phoenix

Sponsor: Polaris Group

Sex: All·Age: 18 - 99

Code: NCT05712694·Phase 3·Recruiting

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Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

for Large B-cell Lymphoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06104592·Phase 2·Recruiting

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Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

11 locations incl. New Haven

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting

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Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

for Cholangiocarcinoma

Drug: Trametinib

10 locations incl. Los Angeles

Sponsor: Genfit

Sex: All·Age: 18+

Code: NCT05874414·Phase 1, Phase 2·Recruiting

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Support Through Remote Observation and Nutrition Guidance Program (STRONG-PCS)

for Pancreatic Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT06001268·Recruiting

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AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

for B-cell Malignancy

13 locations incl. Orange

Sponsor: Carna Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT05602363·Phase 1·Recruiting

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A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

8 locations incl. Jacksonville

Sponsor: Vividion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05954312·Phase 1·Recruiting

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Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

for Myelofibrosis (PMF)

9 locations incl. Tampa

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT05835466·Phase 2·Recruiting

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The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias

for Relapsed or Resistant Acute Leukaemias

5 locations incl. Tampa

Sponsor: Lin BioScience, Inc

Sex: All·Age: 18 - 120

Code: NCT05756322·Phase 1, Phase 2·Recruiting

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Itacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy

for Diffuse Large B Cell Lymphoma

Drug: Itacitinib

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT05757219·Phase 2·Recruiting

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

454 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting

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CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)

for Acute Lymphoblastic Leukemia

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18 - 50

Code: NCT05581030·Phase 1·Recruiting

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

28 locations incl. Los Angeles

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting

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SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma

for Ovarian Cancer

5 locations incl. Tampa

Sponsor: Verismo Therapeutics

Sex: All·Age: 18+

Code: NCT05568680·Phase 1·Recruiting

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Pacritinib in Relapsed/Refractory T-cell Lymphoproliferative Neoplasms

for T-Cell Neoplasm

Drug: Pacritinib

6 locations incl. Duarte

Sponsor: University of Michigan Rogel Cancer Center

Sex: All·Age: 18+

Code: NCT04858256·Phase 2·Recruiting

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

21 locations incl. Birmingham

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting

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Adaptive Therapy of Vismodegib in Advanced Basal Cell Carcinoma

for Advanced Basal Cell Carcinoma

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT05651828·EARLY_Phase 1·Recruiting

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

11 locations incl. La Jolla

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting

Apply to this trial

Outreach Core Activities

for Cancer Education

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05832177·Recruiting

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Testing the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous Treatment

for Recurrent Glioblastoma, IDH-Wildtype

Drug: Selinexor

36 locations incl. Phoenix

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05432804·Phase 1, Phase 2·Recruiting

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Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

for Non Small Cell Lung Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT05681780·Phase 1·Recruiting

Apply to this trial

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

for Thyroid Cancer

6 locations incl. Washington D.C.

Sponsor: Massachusetts General Hospital

Sex: All·Age: 12+

Code: NCT05668962·Phase 2·Recruiting

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Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

for Pancreatic Cancer

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT05687188·Recruiting

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CPX-351 in Combination With Gemtuzumab Ozogamicin in Newly Diagnosed AML

for Acute Myeloid Leukemia

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18 - 70

Code: NCT05558124·Phase 1·Recruiting

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PRE-I-SPY Phase I/Ib Oncology Platform Program

for HER2-positive Breast Cancer

7 locations incl. Birmingham

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT05868226·Phase 1·Recruiting

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Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancer

for Prostate Cancer

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: Male·Age: 18+

Code: NCT05751941·Phase 2·Recruiting

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SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

for Oropharyngeal Cancer

26 locations incl. Corona

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT05451004·Phase 3·Recruiting

Apply to this trial