Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations

Conditions

Blood Sample Collection — OTHER
Participants will have 40 mL of blood drawn at baseline/pre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.
Tissue Sample Collection — OTHER
At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.
Data Collection — OTHER
Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.
Medical Image Collection — OTHER
Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.

This study will evaluate obesity-mediated mechanisms of pancreatic carcinogenesis in minority populations.

Arm: Retrospective Cohort
Retrospective chart review and sample analysis of both pathologically confirmed Pancreatic Ductal Adenocarcinoma (PDAC) cases and non-Cancer control cases.
Arm: Prospective Cohort
Blood samples, tissue samples and data will be collected from all participants as applicable.

Assess molecular and radiological landscape of traditional PDAC tumors in the context of Race/Ethnicity [ Time Frame: at 36 months ]

Facility	City	State	ZIP	Site coordinators
Moffitt Cancer Center	Tampa	Florida	33612	-
University of Mississippi Medical Center	Jackson	Mississippi	39216	Magdeline D Martin [email protected] 352-672-0548 Shannon Orr, MD (PRINCIPAL_INVESTIGATOR)

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