Neurology Clinical Trials in St Louis, MO

As of June 2026, 73 paid clinical trials are recruiting for Neurology in St Louis, Missouri. Neurology trials investigate disease-modifying therapies for Alzheimer's, Parkinson's, multiple sclerosis, ALS, and stroke recovery alongside symptomatic treatments for epilepsy, migraine, and cognitive decline. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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73 clinical trials for Neurology

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Clinical Trial on Agitation in Alzheimer's Dementia

for Alzheimer Disease

23 locations incl. Maitland

Sponsor: IGC Pharma, LLC

Sex: All·Age: 60+

Code: NCT05543681·Phase 2·Recruiting

Apply to this trial

North American Prodromal Synucleinopathy Consortium Stage 2

for REM Sleep Behavior Disorder

8 locations incl. Los Angeles

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05826457·Enrolling By Invitation

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

for Amyloid Plaque

13 locations incl. Phoenix

Sponsor: AC Immune SA

Sex: All·Age: 35 - 85

Code: NCT05462106·Phase 1, Phase 2·Recruiting

Apply to this trial

Sleep Trial to Prevent Alzheimer's Disease

for Sleep

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT04629547·Phase 2·Recruiting

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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)

for Type2 Diabetes

2 locations incl. St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 12 - 17·Accepts healthy volunteers

Code: NCT05277558·Recruiting

Apply to this trial

Amygdala Memory Enhancement

for Brain Diseases

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18 - 75

Code: NCT05065450·Recruiting

Apply to this trial

Alzheimer"s Imaging Biomarkers in Obesity

for Alzheimer Disease

1 location in St Louis

Sponsor: Cyrus A Raji

Sex: All·Age: 40 - 60·Accepts healthy volunteers

Code: NCT05077579·Recruiting

Apply to this trial

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

11 locations incl. Birmingham

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting

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Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

for Alzheimer Disease

1 location in St Louis

Sponsor: Tammie L. S. Benzinger, MD, PhD

Sex: All·Age: 18+

Code: NCT04579120·Recruiting

Apply to this trial

Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

Apply to this trial

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

24 locations incl. Paradise Valley

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting

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Imaging Biomarkers in Preclinical and Symptomatic AD

for Alzheimer Disease

1 location in St Louis

Sponsor: Tammie L. S. Benzinger, MD, PhD

Sex: All·Age: 18+

Code: NCT04134923·Recruiting

Apply to this trial

Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

18 locations incl. Phoenix

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting

Apply to this trial

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

for Amyotrophic Lateral Sclerosis

10 locations incl. Phoenix

Sponsor: Target ALS Foundation, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05137665·Recruiting

Apply to this trial

Intermuscular Coherence as a Biomarker for ALS

for Amyotrophic Lateral Sclerosis

4 locations incl. Irvine

Sponsor: University of Chicago

Sex: All·Age: 20 - 90·Accepts healthy volunteers

Code: NCT05104710·Recruiting

Apply to this trial

F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (DIAN Project)

for Alzheimer Disease

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT02414178·Enrolling By Invitation

Study of Tau Imaging With the Use of [18F]MK-6240 Tracer

for Alzheimer Disease

1 location in St Louis

Sponsor: Tammie L. S. Benzinger, MD, PhD

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04104659·Enrolling By Invitation

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

12 locations incl. Birmingham

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

Apply to this trial

HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

Apply to this trial

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

25 locations incl. Birmingham

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting

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Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease

for Spinal Cord Injuries

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT04457206·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

Apply to this trial

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

51 locations incl. Little Rock

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting

Apply to this trial

Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

51 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting

Apply to this trial

North American Prodromal Synucleinopathy Consortium

for REM Sleep Behavior Disorder

9 locations incl. Sun City

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT03623672·Enrolling By Invitation

Longitudinal Early-onset Alzheimer's Disease Study Protocol

for Early Onset Alzheimer Disease

18 locations incl. Sun City

Sponsor: Indiana University

Sex: All·Age: 40 - 64·Accepts healthy volunteers

Code: NCT03507257·Recruiting

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Late Onset Alzheimer's Disease

for Alzheimer Disease

12 locations incl. Washington D.C.

Sponsor: Columbia University

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT05010603·Recruiting

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F 18 T807 Tau PET Imaging of Alzheimer's Disease

for Alzheimer Disease

1 location in St Louis

Sponsor: Tammie L. S. Benzinger, MD, PhD

Sex: All·Age: 18+

Code: NCT02414347·Recruiting

Apply to this trial

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

for Parkinson's Disease

28 locations incl. Aliso Viejo

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT02071134·Recruiting

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Clinical Outcomes for Deep Brain Stimulation

for Parkinson Disease

1 location in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT03992625·Recruiting

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Dominantly Inherited Alzheimer Network (DIAN)

for Alzheimer's Disease

8 locations incl. Jacksonville

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00869817·Recruiting

Apply to this trial

Conditions in Neurology (St Louis, MO)

Alzheimer's disease· 22 Stroke· 11 Parkinson's disease· 9 Dementia· 7 Multiple sclerosis· 7 ALS (amyotrophic lateral sclerosis)· 6 Epilepsy· 5 Spinal cord injury· 5 Mild cognitive impairment (MCI)· 3 Migraine· 3 Cognitive impairment / decline· 3 Multiple system atrophy· 2 Myasthenia gravis· 2 Traumatic brain injury (TBI)· 2 Essential tremor· 1 Movement disorders· 1