Dominantly Inherited Alzheimer Network (DIAN)
Part of paid clinical trials in Jacksonville, Florida.
- Sponsor
- Washington University School of Medicine
- Study ID
- NCT00869817
- Status
- Recruiting
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Accepted
Study Details
The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Key Dates
- Start date
- Jan 31, 2009
- Status verified
- May 2026
- Primary completion
- Jul 31, 2026
- Completion
- Jul 31, 2026
Study Design
- Enrollment
- 700 participants (estimated)
Arms
- Arm: 1Mutation Positive
- Arm: 2Mutation Negative
Primary Outcome Measure
Positive predictive power of a biomarker or group of biomarkers [ Time Frame: Variable follow-up assessment based on age in relation to age at onset of affected parent. ]
Central Contacts
- Alisha Daniels, MD,MHA(314) 273-9057
- DIAN Obs Admin Core
Locations (8)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | Ercilia Moncayo Twila Morrell, BS Gregory S Day, MD (PRINCIPAL_INVESTIGATOR) |
| Indiana University-Indiana Alzheimer Disease Center | Indianapolis | Indiana | 46202 | Martin Farlow, MD (PRINCIPAL_INVESTIGATOR) |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | Alexa Coussoule Paola Matos Jasmeer Chhatwal, MD, PhD (PRINCIPAL_INVESTIGATOR) |
| Washington University in St. Louis School of Medicine | St Louis | Missouri | 63108 | McCrae Johnson, RN, MSN Georgia Stobbs-Cucchi, RN Randall Bateman, MD (PRINCIPAL_INVESTIGATOR) |
| Columbia University | New York | New York | 10032 | - |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15260 | Sarah Berman, MD, PhD (PRINCIPAL_INVESTIGATOR) |
| Butler Hospital | Providence | Rhode Island | 02906 | Edward Huey, MD (PRINCIPAL_INVESTIGATOR) |
| University of Washington | Seattle | Washington | 98195 | Sarah Taylor Emmaline Seth Suman Jayadev, MD (PRINCIPAL_INVESTIGATOR) |
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