Dominantly Inherited Alzheimer Network (DIAN)

Part of paid clinical trials in Jacksonville, Florida.

Sponsor
Washington University School of Medicine
Study ID
NCT00869817
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.

Key Dates

Start date
Jan 31, 2009
Status verified
May 2026
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
700 participants (estimated)

Arms

  • Arm: 1
    Mutation Positive
  • Arm: 2
    Mutation Negative

Primary Outcome Measure

Positive predictive power of a biomarker or group of biomarkers [ Time Frame: Variable follow-up assessment based on age in relation to age at onset of affected parent. ]

Central Contacts

Locations (8)

FacilityCityStateZIPSite coordinators
Mayo Clinic JacksonvilleJacksonvilleFlorida32224
Ercilia Moncayo
Twila Morrell, BS
Gregory S Day, MD (PRINCIPAL_INVESTIGATOR)
Indiana University-Indiana Alzheimer Disease CenterIndianapolisIndiana46202
Jill Buck, RN
317-963-1847
Martin Farlow, MD (PRINCIPAL_INVESTIGATOR)
Brigham and Women's HospitalBostonMassachusetts02115
Alexa Coussoule
Jasmeer Chhatwal, MD, PhD (PRINCIPAL_INVESTIGATOR)
Washington University in St. Louis School of MedicineSt LouisMissouri63108
McCrae Johnson, RN, MSN
Georgia Stobbs-Cucchi, RN
Randall Bateman, MD (PRINCIPAL_INVESTIGATOR)
Columbia UniversityNew YorkNew York10032-
University of PittsburghPittsburghPennsylvania15260
Zana Ikonomovic, MD
412-692-2740
Sarah Berman, MD, PhD (PRINCIPAL_INVESTIGATOR)
Butler HospitalProvidenceRhode Island02906
Courtney Bodge, PhD
(401) 455-6403
Edward Huey, MD (PRINCIPAL_INVESTIGATOR)
University of WashingtonSeattleWashington98195
Sarah Taylor
Emmaline Seth
Suman Jayadev, MD (PRINCIPAL_INVESTIGATOR)

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