Late Onset Alzheimer's Disease
Part of paid clinical trials in Washington D.C., District of Columbia.
- Sponsor
- Columbia University
- Study ID
- NCT05010603
- Status
- Recruiting
Conditions
Eligibility Criteria
- Sex
- ALL
- Age
- 55 Years - N/A
- Healthy Volunteers
- Accepted
Interventions
- Blood Draw — GENETICCollection of blood samples for genetic testing
- Late Onset Alzheimer's Disease (LOAD) Neuropsychological Battery Test — OTHERMemory Test
Study Details
The goal of this study is to is to focus on the genetic influences on Alzheimer's Disease (AD) risk. The investigators are looking for families and/or individuals (affected or unaffected) of any ethic background (African American, Caucasian, and Hispanics) with a family history of AD and willing to participate.
Key Dates
- Start date
- Nov 15, 2016
- Status verified
- May 2026
- Primary completion
- Apr 30, 2027
- Completion
- Apr 30, 2027
Study Design
- Enrollment
- 10,000 participants (estimated)
Arms
- Arm: Families with a history of Alzheimer's DiseaseFamilies with two or more family members affected with Alzheimer's Disease
- Arm: Un-related, non-demented controlsUn-related, non-demented healthy controls over age 55
- Arm: Individuals with Dementia (Alzheimer's Disease)Individuals with dementia over the age of 65
Primary Outcome Measure
Total number of genes identified to be associated with the risk of AD [ Time Frame: 5 years ]
Central Contacts
- Dolly Reyes-Dumeyer212-305-5953
- Amanda Chan917-696-3082
Locations (12)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Washington | Washington D.C. | District of Columbia | 98105 | Sarah Payne |
| University of Miami | Miami | Florida | 33124 | Larry Deon |
| Rush University | Aurora | Illinois | 60612 | Corey Woods |
| Indiana University | Bloomington | Indiana | 47405 | Kelly Farber |
| NCRAD at Indiana University | Indianapolis | Indiana | 46202 | Kelly Farber |
| Mayo Clinic | Rochester | Minnesota | 55901 | Christine Hanzel |
| Joanne Norton | St Louis | Missouri | 63130 | Joanne Norton |
| Columbia University Irving Medical Center | New York | New York | 10032 | Richard P Mayeux, MD, MSc (PRINCIPAL_INVESTIGATOR) Christiane Reitz, MD, PhD (SUB_INVESTIGATOR) Ruth Ottman, PhD (SUB_INVESTIGATOR) |
| North Carolina State University | Raleigh | North Carolina | 27695 | Takiyah Starks |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | Elise Weamer |
| University of Texas Southwestern | Dallas | Texas | 75390 | Amy Browning |
| University of Washington | Seattle | Washington | 98195 | - |
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