Paid Clinical Trials in South Carolina

South Carolina has 1,276 paid clinical trials enrolling now across cities including Charleston, Greenville and Columbia. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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1,276 clinical trials

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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

4 locations incl. Glendale

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting

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Simeox 200 US Study

for Bronchiectasis

1 location in Charleston

Sponsor: Inogen Inc.

Sex: All·Age: 18 - 85

Code: NCT07443124·Not Yet Recruiting

A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)

for Liver Cirrhosis

Drug: BI 3802876

26 locations incl. Chandler

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18 - 75

Code: NCT07325526·Phase 2·Recruiting

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A Study to Assess the Effectiveness and Safety of IPN10200 in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows

for Moderate to Severe Glabellar Lines

Drug: IPN10200

17 locations incl. Birmingham

Sponsor: Ipsen

Sex: All·Age: 18 - 80

Code: NCT07427797·Phase 3·Recruiting

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AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

for Obesity

Drug: NNC0487-0111

22 locations incl. Miramar

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07339423·Phase 3·Recruiting

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REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

for PTSD - Post Traumatic Stress Disorder

5 locations incl. Aurora

Sponsor: Senseye, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07280065·Phase 3·Recruiting

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

48 locations incl. Gilbert

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

20 locations incl. Goodyear

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting

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Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

for Locally Advanced Adrenal Cortical Carcinoma

Drug: Cabozantinib

69 locations incl. La Jolla

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12+

Code: NCT06900595·Phase 2·Recruiting

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AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

for Corneal Edema

12 locations incl. Mesa

Sponsor: Aurion Biotech

Sex: All·Age: 18+

Code: NCT07368959·Phase 3·Recruiting

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Ambulatory Long Length URodynamics Evaluation

for Urology

7 locations incl. Hanover

Sponsor: Bright Uro

Sex: All·Age: 22+

Code: NCT07425015·Recruiting

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COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

for Diabetic Macular Edema

Drug: Aflibercept

50 locations incl. Bakersfield

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07449936·Phase 3·Recruiting

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Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

309 locations incl. Phoenix

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting

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Tele-PCIT for Healthy Relationships in Families At-Risk

for Disruptive Behavior

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 7

Code: NCT07225010·Recruiting

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Dietary Insights and Nutrition Experiences in Adults on GLP-1 Therapy - A Study on Diet Quality Changes in Adults on GLP-1 Therapy

for Obesity Type 2 Diabetes Mellitus

2 locations incl. Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+

Code: NCT07313384·Recruiting

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A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

for Moderate to Severe Chronic Obstructive Pulmonary Disease

Drug: PF-07275315

30 locations incl. Dothan

Sponsor: Pfizer

Sex: All·Age: 35 - 80

Code: NCT07363694·Phase 2, Phase 3·Recruiting

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Engaging Pharmacists to Advance Tobacco Treatment Service Delivery

for Smoking Cessation

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 21+

Code: NCT07501624·Enrolling By Invitation

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

for Familial Pulmonary Fibrosis

Drug: Nerandomilast

13 locations incl. Los Angeles

Sponsor: Boehringer Ingelheim

Sex: All·Age: 40+

Code: NCT07201922·Phase 3·Recruiting

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A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

16 locations incl. Tucson

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2·Recruiting

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Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for Carcinoma, Renal Cell

Drug: PF-08634404

101 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227415·Phase 1, Phase 2·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

for Sleep Apnea, Obstructive

Drug: Eloralintide

23 locations incl. Cullman

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07369011·Phase 3·Recruiting

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A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

for Uncontrolled Gout

48 locations incl. Birmingham

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07388498·Phase 3·Recruiting

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CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

for Diabetic Macular Edema

Drug: Aflibercept

48 locations incl. Gilbert

Sponsor: EyePoint Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07449923·Phase 3·Recruiting

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A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System

for Post Traumatic Arthritis

4 locations incl. Morton Grove

Sponsor: Stryker Trauma and Extremities

Sex: All·Age: 21+

Code: NCT07118501·Recruiting

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A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

for Obesity

Drug: Eloralintide

41 locations incl. Tuscaloosa

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07321886·Phase 3·Recruiting

Apply to this trial

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

for Type II Diabetes Mellitus

31 locations incl. Birmingham

Sponsor: Corxel Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT07340320·Phase 2·Recruiting

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A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia

for Dystonia

37 locations incl. Birmingham

Sponsor: Vima Therapeutics

Sex: All·Age: 18 - 65

Code: NCT07304089·Phase 2·Recruiting

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

11 locations incl. Riverside

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting

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The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention

for Sleep Apnea, Obstructive

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 2 - 12

Code: NCT06828835·Recruiting

Apply to this trial

Brain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)

for Brain Metastases

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07227610·Phase 2·Recruiting

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GLP1 Fasting Status and Gastric Retention Using Gastric Ultrasound

for Gastric Retention

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07251803·Recruiting

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

77 locations incl. Phoenix

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

11 locations incl. Birmingham

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting

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Hypofractionated Radiotherapy With a Focal Microboost for High-Risk and Locally Advanced Prostate Cancer

for Prostate Cancer

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: Male·Age: 18+

Code: NCT07325721·Phase 2·Recruiting

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Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

for HFrEF - Heart Failure With Reduced Ejection Fraction

7 locations incl. San Francisco

Sponsor: Columbia University

Sex: All·Age: 18+

Code: NCT07335510·Not Yet Recruiting

Behavioral Health Collaborative Care Model in an ICU Recovery Clinic

for PICS

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07372586·Recruiting

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Behavioral Health Collaborative Care Model in Post-ICU Clinic Family Pilot

for Critical Illness Recovery

1 location in Charleston

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT07390786·Recruiting

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Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

for Opioid Use Disorder

Drug: Tirzepatide

9 locations incl. Jacksonville

Sponsor: T. John Winhusen, PhD

Sex: All·Age: 18+

Code: NCT06651177·Phase 2·Recruiting

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A Trial of TAK-861 for the Treatment of Narcolepsy With Cataplexy

for Narcolepsy Type 1 (NT1)

11 locations incl. Redwood City

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT07363720·Phase 3·Recruiting

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Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)

for Hepatitis

Drug: Larsucosterol

48 locations incl. Birmingham

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 18+

Code: NCT07428538·Phase 3·Recruiting

Apply to this trial