RecruitingPhase 2Radiation therapyBrain Metastases in Greater Size - Hypofractionated Options Trial (BIGSHOT)This is a randomized, phase II trial comparing staged stereotactic radiosurgery (SSRS) versus fractionated stereotactic radiotherapy (FSRT) in patients with large brain metastases (≥2 cm and ≤5 cm). The study aims to evaluate efficacy, safety, and tumor response between these two standard-of-care radiation approaches.