Clinical Trials at University of Rochester

As of June 2026, 188 paid clinical trials are recruiting at University of Rochester, located at 601 ELMWOOD AVE, BOX 684, ROCHESTER, NY 14642-0002, phone (585) 275-2100 in Rochester, New York. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 12, 2026.

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188 clinical trials at University of Rochester

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

Apply to this trial

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

for Advanced Colorectal Carcinoma

225 locations incl. Fort Smith

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT06073431·Recruiting

Apply to this trial

A Single Arm Pilot Trial of a Social Network Intervention

for Cancer

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 60+

Code: NCT05745038·Recruiting

Apply to this trial

Vision Loss Impact on Navigation in Virtual Reality

for Stroke, Ischemic

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT06047717·Recruiting

Apply to this trial

Remote Assessments and Genetic Determinants of Congenital and Childhood Myotonic Dystrophy

for Myotonic Dystrophy Type 1

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 0 - 17

Code: NCT07630389·Recruiting

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

37 locations incl. Scottsdale

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting

Apply to this trial

Access to Genetic Testing in Underserved Patients With Cancer

for Breast Carcinoma

2 locations incl. Los Angeles

Sponsor: University of Southern California

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06422455·Recruiting

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A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for Lymphoma

Drug: Glofitamab

18 locations incl. Berkeley

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06084936·Phase 3·Recruiting

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Testing Continuous Versus Intermittent Treatment With the Study Drug Zanubrutinib for Older Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

237 locations incl. Little Rock

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 60+

Code: NCT05976763·Phase 3·Recruiting

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

1208 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting

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Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

for Hodgkin Lymphoma

428 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT06002828·Recruiting

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Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

for Plasma Cell Myeloma

397 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: All ages

Code: NCT05561387·Phase 3·Recruiting

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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

for Metastatic Colorectal Adenocarcinoma

184 locations incl. Kingman

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05673148·Phase 3·Recruiting

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AWARE: Management of ADHD in Autism Spectrum Disorder

for ADHD

10 locations incl. Irvine

Sponsor: Daniel Coury

Sex: All·Age: 4 - 17

Code: NCT05916339·Phase 4·Recruiting

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Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

for Grade 3b Follicular Lymphoma

104 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05890352·Phase 2·Recruiting

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

955 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting

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Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma

for Smoldering Multiple Myeloma

Drug: Selinexor

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05597345·Phase 2·Recruiting

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Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

470 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05624996·Phase 3·Recruiting

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

820 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting

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Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

for Diffuse Large B-Cell Lymphoma

87 locations incl. Tucson

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05633615·Phase 2·Recruiting

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Alzheimer's Disease Neuroimaging Initiative 4

for Mild Cognitive Impairment

59 locations incl. Birmingham

Sponsor: University of Southern California

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05617014·Enrolling By Invitation

Exercise and Cognitive Rehab in Older Cancer Survivors

for Cancer

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 60+

Code: NCT05388214·Recruiting

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A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

for Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

Drug: Nivolumab

390 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 5 - 60

Code: NCT05675410·Phase 3·Recruiting

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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

454 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642572·Phase 2·Recruiting

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Geriatric Evaluation and Management With Survivorship Health Education for Older Survivors of Cancer, GEM-S Trial

for Lymphoma

45 locations incl. Tuscaloosa

Sponsor: University of Rochester

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05006482·Phase 3·Recruiting

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A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

for High Grade Osteosarcoma

Drug: Cabozantinib

175 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 40

Code: NCT05691478·Phase 2, Phase 3·Recruiting

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

785 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

403 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting

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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

for Ulcerative Colitis

22 locations incl. Irvine

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT05230173·Recruiting

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Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance

for Barrett Esophagus

14 locations incl. Gilbert

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 89

Code: NCT05530343·Recruiting

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Trial of Neratinib Plus Capecitabine in Subjects With HER2-Negative Metastatic Breast Cancer With Brain Metastases and Abnormally Active HER2 Signaling

for Breast Cancer

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT04965064·Phase 2·Recruiting

Apply to this trial

Povidone Iodine Efficacy Study

for Early Childhood Caries

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 24 Months - 71 Months·Accepts healthy volunteers

Code: NCT05272254·Phase 2·Recruiting

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Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer

for Pancreatic Cancer Metastatic

14 locations incl. Hot Springs

Sponsor: Panbela Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05254171·Phase 2, Phase 3·Recruiting

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

165 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting

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Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

for Peripartum Cardiomyopathy, Postpartum

64 locations incl. Birmingham

Sponsor: Dennis M. McNamara, MD, MS

Sex: Female·Age: 18+

Code: NCT05180773·Phase 4·Recruiting

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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

1021 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting

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Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

for Endometrial Adenocarcinoma

Drug: Ipilimumab

137 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05112601·Phase 2·Recruiting

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Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

for Relapsed Adult AML

20 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05237258·Recruiting

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

19 locations incl. Phoenix

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting

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Remote Assessments and Genetic Determinants of Myotonic Dystrophy

for Myotonic Dystrophy Type 1 (DM1)

1 location in Rochester

Sponsor: University of Rochester

Sex: All·Age: 18 - 88

Code: NCT07505342·Recruiting

Apply to this trial