Paid Clinical Trials in Rochester, MN

As of June 2026, 1,307 paid clinical trials are recruiting in Rochester, Minnesota. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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1,307 clinical trials

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Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

for Indigestion

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT03865290·Phase 2·Recruiting

Apply to this trial

Long-Term Real-World Outcomes Study on Patients Implanted With a Neurostimulator

for Chronic Pain

30 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT03876054·Recruiting

Apply to this trial

Investigation of Neurocognitive Measures of Sport-Related Injury

for Concussion, Brain

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 12 - 30

Code: NCT03414242·Enrolling By Invitation

Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

1229 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting

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Understanding Mechanisms of Normal and Disordered Defecation

for Constipation

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03842007·Recruiting

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Intramyocellular Fatty Acid Trafficking in Insulin Resistance States - Effects of Intestinal Delivery of Lipids

for Insulin Resistance

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT03818178·Recruiting

Apply to this trial

Pulmonary Hemodynamics During Exercise - Research Network

for Pulmonary Circulation Diseases

8 locations incl. Phoenix

Sponsor: Medical University of Graz

Sex: All·Age: 18+

Code: NCT03954574·Recruiting

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IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry

for Ventricular Arrhythmia

34 locations incl. Phoenix

Sponsor: University of California, Los Angeles

Sex: All·Age: All ages

Code: NCT04520347·Enrolling By Invitation

Neuroimaging Study

for Cognitive Impairment

2 locations incl. Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT03618186·Phase 2·Enrolling By Invitation

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors

for Malignant Solid Neoplasm

4 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03750227·Phase 3·Recruiting

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Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Adults

for Frail Elderly Syndrome

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 70+

Code: NCT03675724·Phase 2·Enrolling By Invitation

Insulin Regulation of Lipolysis and Lipolysis Proteins

for Obesity

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT03866408·EARLY_Phase 1·Recruiting

Apply to this trial

Mayo Clinic IBD Biobank

for Inflammatory Bowel Diseases

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT03756649·Enrolling By Invitation

Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia

for Renal Failure Congenital

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: All ages

Code: NCT03723564·Phase 1·Recruiting

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Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

for Castration Levels of Testosterone

334 locations incl. Gilbert

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT03678025·Phase 3·Recruiting

Apply to this trial

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

for Melanoma Stage IIIB

19 locations incl. Phoenix

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT03567889·Phase 3·Recruiting

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Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03516617·Phase 2·Recruiting

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ATrial Tachycardia PAcing Therapy in Congenital Heart

for Atrial Arrhythmia

14 locations incl. Los Angeles

Sponsor: Ian Law

Sex: All·Age: All ages

Code: NCT03209583·Recruiting

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Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

for Ascending Aortic Aneurysm Enlargement

15 locations incl. San Francisco

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18 - 79

Code: NCT03536312·Recruiting

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North American Prodromal Synucleinopathy Consortium

for REM Sleep Behavior Disorder

9 locations incl. Sun City

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT03623672·Enrolling By Invitation

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

for Solid Tumors

65 locations incl. Tucson

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT03486873·Phase 3·Recruiting

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Creation of a Biospecimen Repository From Patients With Interstitial Lung Diseases (ILD)

for Interstitial Lung Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03478826·Recruiting

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Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

for Neoplasms

100 locations incl. Birmingham

Sponsor: Celgene

Sex: All·Age: All ages

Code: NCT03435796·Phase 2, Phase 3·Recruiting

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Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

for PPA

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT01818661·Phase 4·Recruiting

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Longitudinal Imaging Biomarkers of Disease Progression in DLB

for Lewy Body Disease

2 locations incl. Jacksonville

Sponsor: Kejal Kantarci

Sex: All·Age: 18+

Code: NCT03582488·Phase 4·Enrolling By Invitation

CEUS for Blunt Abdominal Trauma in Children

for Trauma Abdomen

2 locations incl. Rochester

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 0 - 17

Code: NCT03490929·Phase 4·Recruiting

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Study of REGN4018 (Ubamatamab) Administered Alone or in Combination With Cemiplimab in Adult Patients With Recurrent Ovarian Cancer or Other Recurrent Mucin-16 Expressing (MUC16+) Cancers

for Recurrent Ovarian Cancer

Drug: Cemiplimab

11 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT03564340·Phase 1, Phase 2·Recruiting

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

152 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting

Apply to this trial

Molecular Detection of Advanced Neoplasia in Pancreatic Cysts

for Pancreas Cyst

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 120

Code: NCT03855800·Recruiting

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Longitudinal Early-onset Alzheimer's Disease Study Protocol

for Early Onset Alzheimer Disease

18 locations incl. Sun City

Sponsor: Indiana University

Sex: All·Age: 40 - 64·Accepts healthy volunteers

Code: NCT03507257·Recruiting

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Anterior Vertebral Body Tethering (AVBT) Using Zimmer Biomet Tether System or Dynesys System Components to Treat Pediatric Scoliosis

for Scoliosis

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 10 - 16

Code: NCT03506334·Enrolling By Invitation

Shared Decision Making to Improve Goals of Care in the ED

for Goals

3 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 60+

Code: NCT03833622·Recruiting

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Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia

for Clonal Cytopenia of Undetermined Significance

4 locations incl. Mankato

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT03418038·Phase 2·Recruiting

Apply to this trial

Gynecologic Extramammary Paget's Disease

for Extramammary Paget's Disease

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT03564483·Recruiting

Apply to this trial

Mayo AVC Registry and Biobank

for Arrhythmogenic Right Ventricular Cardiomyopathy

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT03049254·Recruiting

Apply to this trial

Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women

for Frail Elderly Syndrome

1 location in Rochester

Sponsor: Mayo Clinic

Sex: Female·Age: 70+

Code: NCT03430037·Phase 2·Enrolling By Invitation

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

for Obstructive Sleep Apnea of Adult

1 location in Rochester

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT03307330·Recruiting

Apply to this trial

Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction

for Lower Urinary Tract Obstructive Syndrome

2 locations incl. Miami

Sponsor: Rodrigo Ruano

Sex: Female·Age: 18+

Code: NCT03281798·Recruiting

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CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for Relapsed Hematologic Malignancy

Drug: Emavusertib

27 locations incl. Phoenix

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT03328078·Phase 1, Phase 2·Recruiting

Apply to this trial